Mesenteric Resistance Arteries
Mostrando 1-12 de 28 artigos, teses e dissertações.
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1. A obesidade diminui a resposta de artérias mesentéricas de resistência a agonistas canabinóides. / Obesity decreases the response of resistance mesenteric arteries to cannabinoid agonists.
Este estudo investigou o efeito da obesidade sobre a resposta de artérias mesentéricas a agonistas canabinóides. Ratos obesos Zucker (OZRs) apresentaram reduzido relaxamento à anandamida, aos agonistas CB1 e CB2 e à capsaicina (agonista vanilóide) comparados aos controles (LZRs). A expressão dos receptores CB1 e CB2 foi menor em OZRs. O bloqueio de ca
Publicado em: 2010
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2. Time-dependent effect of chronic ouabain administration in rats on blood pressure and vascular reactivity in mesenteric resistance arteries: the possible mechanisms involved. / Efeito da administração crônica a longo prazo de ouabaína sobre a pressão arterial e a reatividade vascular de artérias mesentéricas de resistência de rato: possíveis mecanismos envolvidos.
A ouabaína (OUA) promoveu hipertensão arterial (HA) após 5, 10 e 20 semanas de tratamento e modificou a função vascular de artérias mesentéricas de resistência (AMR). O tratamento por 5 semanas com OUA aumentou o óxido nítrico (NO) e a expressão protéica da isoforma neuronal de óxido nítrico (nNOS), ao passo que diminuiu os prostanóides vasoco
Publicado em: 2007
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3. Impaired flow-induced dilation in mesenteric resistance arteries from mice lacking vimentin.
The intermediate filament vimentin might play a key role in vascular resistance to mechanical stress. We investigated the responses to pressure (tensile stress) and flow (shear stress) of mesenteric resistance arteries perfused in vitro from vimentin knockout mice. Arteries were isolated from homozygous (Vim-/-, n = 14) or heterozygous vimentin-null mice (Vi
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4. TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure
Transient receptor potential vanilloid 4 (TRPV4) channels have been implicated as mediators of calcium influx in both endothelial and vascular smooth muscle cells and are potentially important modulators of vascular tone. However, very little is known about the functional roles of TRPV4 in the resistance vasculature or how these channels influence hemodynami
American Physiological Society.
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5. Enalapril Treatment Alters the Contribution of Epoxyeicosatrienoic Acids but Not Gap Junctions to Endothelium-Derived Hyperpolarizing Factor Activity in Mesenteric Arteries of Spontaneously Hypertensive Rats
Reduction in endothelium-derived hyperpolarizing factor (EDHF)-mediated dilatory function in large, elastic arteries during hypertension is reversed after blood pressure normalization. We investigated whether similar mechanisms occurred in smaller mesenteric resistance arteries from aged Wistar-Kyoto (WKY) rats, spontaneously hypertensive rats (SHRs), an
American Society for Pharmacology and Experimental Therapeutics.
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6. Arterial internal elastic lamina holes: relationship to function?
Internal elastic lamina (IEL) hole (fenestration) characteristics and myoendothelial gap junction (MEGJ) density were examined in selected resistance and conduit arteries of normal and diseased rat and mouse models, using conventional, ultrastructural and confocal microscopy methods. Selected vessels were those commonly used in functional studies: thoracic a
Blackwell Science Inc.
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7. Mesenteric blood pressure profile of conscious, freely moving rats.
1. Blood pressure has been measured in the aorta and at four points in the mesenteric circulation of conscious, freely moving rats under physiological, resting conditions. 2. Using small polythene catheters, blood pressure was measured simultaneously in the aorta and either distally in the superior mesenteric artery (group A), at the base of a mesenteric art
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8. Isolated mesenteric arteries from pregnant rats show enhanced flow-mediated relaxation but normal myogenic tone.
1. The mechanisms of vascular adaptation to pregnancy remain to be fully elucidated. In this study we have compared flow-induced dilatation and myogenic responses in fifth generation mesenteric arteries from late pregnant and non-pregnant Wistar rats. 2. Myogenic tone, assessed as the difference between internal diameter (i.d.) in the presence and absence of
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9. Intestinal blood flow is controlled by both feed arteries and microcirculatory resistance vessels in freely moving rats.
1. In freely moving rats, intestinal blood flow, aortic blood pressure and blood pressure at the base of mesenteric arcades were measured simultaneously so as to determine the role of feed arteries and of the microcirculation in the control of intestinal vascular resistance. Segmental resistances of feed arteries (Rfeed) and of microcirculatory vessels (Rmic
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10. Low-dose ouabain constricts small arteries from ouabain-hypertensive rats: implications for sustained elevation of vascular resistance
Prolonged ouabain administration to normal rats causes sustained blood pressure (BP) elevation. This ouabain-induced hypertension (OH) has been attributed, in part, to the narrowing of third-order resistance arteries (∼320 μm internal diameter) as a result of collagen deposition in the artery media (see Ref. 6). Here we describe the structural and functio
American Physiological Society.
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11. Nitroxyl anion – the universal signalling partner of endogenously produced nitric oxide?
Although it is generally assumed that the primary product of the three isoforms of NO synthase is the nitric oxide radical (NO•), growing evidence suggests that the one-electron reduced form of nitrogen monoxide, nitroxyl anion (NO−), may be a natural co-product. Thus, evidence from conduit and resistance arteries and nitrergically innervated tissues ind
Blackwell Publishing Ltd.
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12. The presynaptic regulation of noradrenaline release differs in mesenteric arteries of the rabbit and guinea-pig.
Prejunctional control mechanisms of neuromuscular transmission in mesenteric arteries of the guinea-pig and rabbit were compared by examining excitatory junction potentials (e.j.p.s). The various agents used did not modify the membrane potential or resistance of smooth muscle cells of either tissue at the concentrations used in the present experiments. In th