Metabolic Disorder
Mostrando 1-12 de 180 artigos, teses e dissertações.
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1. Oxidative Stress and Changes of Important Metabolic Gene Expressions as a Potential Biomarker in the Diagnosis of Atherosclerosis in Leukocytes
ABSTRACT Introduction: Presenilin 1 (PSEN1), catalase (CAT), glutathione-S-transferase (GST) and paraoxonase 1 (PON1) play a vital role in prediction, diagnosis and therapy of metabolic disorders. Methods: Metabolic enzyme activities and lipid peroxidation in serum of cerebrovascular diseases (CVD) and coronary artery diseases were measured by spectrophoto
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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2. Central adrenal insufficiency: who, when, and how? From the evidence to the controversies – an exploratory review
ABSTRACT Central adrenal insufficiency (CAI) is a life-threatening disorder. This occurs when ACTH production is insufficient, leading to low cortisol levels. Since corticosteroids are crucial to many metabolic responses under organic stress and inflammatory conditions, CAI recognition and prompt treatment are vital. However, the diagnosis of CAI is challeng
Archives of Endocrinology and Metabolism. Publicado em: 2022
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3. Celiac disease and bone
Abstract Celiac disease (CD) is an autoimmune disorder characterized by small intestinal inflammation triggered by gluten ingestion in genetically-predisposed individuals. A frequent extra-intestinal manifestation of CD is metabolic bone disease which contributes to an increased risk of fracture. The mechanisms underlying bone disease in CD remain incomplete
Archives of Endocrinology and Metabolism. Publicado em: 2022
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4. Discovery of Thiopyrimidinone Derivatives as a New Class of Human Aldose Reductase Inhibitors
Diabetes is a chronic metabolic disorder characterized by insufficient insulin production, the cells’ inability to use this insulin, or a combination of both, leading to secondary complications such as diabetic neuropathy and retinopathy. One way to prevent or control such complications is the use of aldose reductase (AR) inhibitors. In this work, we synth
Journal of the Brazilian Chemical Society. Publicado em: 2022
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5. The relation of dermcidin with insulin resistance and inflammation in women with polycystic ovary syndrome
SUMMARY OBJECTIVE: Polycystic ovary syndrome is the most common endocrinopathy among women of reproductive age. Polycystic ovary syndrome is a metabolic disorder associated with insulin resistance and subclinical inflammation. Dermcidin, an antimicrobial peptide, involves in insulin resistance and inflammatory processes. Dermcidin suppresses the secretion o
Revista da Associação Médica Brasileira. Publicado em: 2022
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6. Impact of metabolic syndrome and clinical features on functioning in patients with bipolar disorder: a cross-sectional study
Objective: The metabolic syndrome (MS) is highly prevalent among patients with bipolar disorder (BD), and may affect progression, functioning, and comorbid conditions in BD. The aim of this study was to investigate the effect of clinical variables and MS on overall functioning and specific areas of functioning in patients with BD. Methods: A total of 210 p
Braz. J. Psychiatry. Publicado em: 2020-08
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7. Prevalência de Síndrome Metabólica e associação com estado nutricional em adolescentes
Resumo Introdução A síndrome metabólica é uma desordem multifatorial relacionada, principalmente, com a deposição de gordura abdominal e as alterações da homeostase da glicose e/ou resistência à insulina. Estudos demonstram associações entre o excesso de peso na infância e as taxas de morbimortalidade elevadas na vida adulta; portanto, a prese
Cad. saúde colet.. Publicado em: 25/11/2019
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8. EFFECTS OF AEROBIC EXERCISE TRAINING ON OXIDATIVE STRESS IN THE SKELETAL MUSCLES OF OBESE RATS
RESUMO Introdução Obesidade é uma desordem metabólica complexa e multifatorial, caracterizada pelo acúmulo de gordura corporal. O exercício físico tem a capacidade de aumentar o gasto energético e promover efeito reparador por meio da modulação das defesas antioxidantes endógenas. Objetivo Avaliar os efeitos da dieta hiperlipídica (DHL) sobre
Rev Bras Med Esporte. Publicado em: 07/10/2019
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9. Metabolic dysregulation in early onset psychiatric disorder before and after exposure to antipsychotic drugs
Antipsychotic Drugs (APDs) are being widely prescribed to treat various disorders, including schizophrenia and bipolar disorder; however, abnormal glucose metabolism and weight gain have been reported with Atypical Anti-Psychotic drugs (AAPDs) that can lead to insulin-resistance and type 2 diabetes mellitus. The study was designed to assess various biochemic
Braz. J. Pharm. Sci.. Publicado em: 30/09/2019
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10. Relationship between dentition, anthropometric measurements, and metabolic syndrome in the elderly
Resumo Introdução A perda dentária é um distúrbio de saúde dos idosos que pode levar à deficiência mastigatória e riscos nutricionais, induzindo alterações bioquímicas da síndrome metabólica (SM). Objetivo Verificar a relação entre número de dentes, medidas antropométricas e SM em um grupo de idosos. Material e método O estudo foi desen
Rev. odontol. UNESP. Publicado em: 12/09/2019
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11. Serum level of cathelicidin LL-37 is increased in euthymic patients with bipolar disorder irrespective of their cardio-metabolic status
Abstract Background Antimicrobial peptides are components of the innate immune system. Cathelicidin LL-37 plays an important role in antimicrobial defense, exerts proinflammatory effect and strongly affects the immune system functioning. Our recent study revealed that serum concentration of LL-37 is increased in patients with bipolar disorder. Objectives
Arch. Clin. Psychiatry (São Paulo). Publicado em: 29/07/2019
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12. Inborn Errors of Intermediary Metabolism in Critically Ill Mexican Newborns
Abstract Inborn errors of intermediary metabolism (IEiM) are complex diseases with high clinical heterogeneity, and some patients who have severe enzyme deficiencies or are subjected to stress (catabolism/infections) actually decompensate in the neonatal period. In this study, we performed metabolic tests on 2025 newborns in Mexico admitted to 35 neonatal in
J. inborn errors metab. screen.. Publicado em: 15/07/2019