Metabolic Profiling
Mostrando 1-12 de 77 artigos, teses e dissertações.
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1. METABOLIC PROFILING AND CYTOTOXIC ACTIVITY OF METHANOL EXTRACTS FROM CHAMAECRISTA DUCKEANA (P. BEZERRA & A. FERN.) H. S. IRWIN & BARNEBY (LEGUMINOSAE, CAESALPINIOIDEAE)
The genus Chamaecrista comprises more than 330 species, with only a few studies on their chemical composition and biologic activities. In this study, the phytochemical profile of leaf, stems, and fruits extracts of the C. duckeana were examined by UPLC ESI HRMS analysis to determine possibly bioactive constituents. The antioxidant activity was carried out th
Química Nova. Publicado em: 2022
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2. Development and application of a test mixture for untargeted liquid chromatography-mass spectrometry analysis of urine samples
Metabolic profiling of complex biological matrices based on liquid chromatography-mass spectrometry (LC-MS) allows detecting a wide range of metabolites with distinct concentrations and physicochemical properties. Given the complexity of samples and the necessity of a comprehensive approach in untargeted metabolomics, quality control strategies are mandatory
Química Nova. Publicado em: 2022
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3. The Gene Ontology Differs in Bursa of Fabricius Between Two Breeds of Ducks Post Hatching by Enriching the Differentially Expressed Genes
ABSTRACT The bursa of Fabricius (BF) is the central humoral immune organ unique to birds. The present study investigated the possible difference on a molecular level between two duck breeds. The digital gene expression profiling (DGE) technology was used to enrich the differentially expressed genes (DEGs) in BF between the Jianchang and Nonghua-P strains of
Rev. Bras. Cienc. Avic.. Publicado em: 2018-03
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4. Metabolomics as a promising tool for early osteoarthritis diagnosis
Osteoarthritis (OA) is the main cause of disability worldwide, due to progressive articular cartilage loss and degeneration. According to recent research, OA is more than just a degenerative disease due to some metabolic components associated to its pathogenesis. However, no biomarker has been identified to detect this disease at early stages or to track its
Braz J Med Biol Res. Publicado em: 21/09/2017
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5. Proteomic profiling of liver from Elaphe taeniura, a common snake in eastern and southeastern Asia
Snake liver has been implicated in the adaptation of snakes to a variety of habitats. However, to date, there has been no systematic analysis of snake liver proteins. In this study, we undertook a proteomic analysis of liver from the colubrid snake Elaphe taeniura using a combination of two-dimensional electrophoresis (2-DE) and matrix-assisted laser desorpt
Genet. Mol. Biol.. Publicado em: 2013
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6. Analysis of acylcarnitine profiles in umbilical cord blood and during the early neonatal period by electrospray ionization tandem mass spectrometry
Acylcarnitine profiling by electrospray ionization tandem mass spectrometry (ESI-MS/MS) is a potent tool for the diagnosis and screening of fatty acid oxidation and organic acid disorders. Few studies have analyzed free carnitine and acylcarnitines in dried blood spots (DBS) of umbilical cord blood (CB) and the postnatal changes in the concentrations of thes
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-06
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7. Serum metabolic profiling of human gastric cancer based on gas chromatography/mass spectrometry
Research on molecular mechanisms of carcinogenesis plays an important role in diagnosing and treating gastric cancer. Metabolic profiling may offer the opportunity to understand the molecular mechanism of carcinogenesis and help to non-invasively identify the potential biomarkers for the early diagnosis of human gastric cancer. The aims of this study were to
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-01
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8. A proton nuclear magnetic resonance-based metabonomics study of metabolic profiling in immunoglobulin a nephropathy
OBJECTIVES: Immunoglobulin A nephropathy is the most common cause of chronic renal failure among primary glomerulonephritis patients. The ability to diagnose immunoglobulin A nephropathy remains poor. However, renal biopsy is an inconvenient, invasive, and painful examination, and no reliable biomarkers have been developed for use in routine patient evaluati
Clinics. Publicado em: 2012
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9. Aspectos fisiológicos e da produção do arroz em resposta ao silício / Physiological and productive aspects of rice plants according to silicon supplying
The objective of this study was to analyze the role of supplemental silicon (Si) in the biomass accumulation and grain yield of rice (Oryza sativa L.). Different experiments were carried out in which wild rice plants (japonica subsp. Oochikara - WT) and mutant defective for the absorption of Si - lsi1 (Low silicon rice 1) were raised under hydroponics condit
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/09/2011
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10. H-NMR metabolic profiling of wines from three cultivars, three soil types and two contrasting vintages
2007
Journal International des Sciences de la Vigne et du Vin. Publicado em: 2011
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11. H-NMR metabolic profiling of wines from three cultivars, three soil types and two contrasting vintages.
Differences in wine flavour proceed primarily from grape quality. Environmental factors determined by the climate, soil and training systems modify many grape and wine quality traits. Metabolic profiling based on proton nuclear magnetic resonance (¹H-NMR) spectra has been proved to be useful to study multifactorial effects of the vine environment on intrica
CONGRÈS INTERNATIONAL DES TERROIRS VITICOLES. Publicado em: 2011
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12. Automatic in-vivo MRS signal quantification for the classification of brain tumors / Quantificação de sinais de MRS do cerebro in-vivo para classificação de tumores
The aim of this work was to study and validate techniques for pre-processing and quantificating Magnetic Resonance Spectroscopy data, obtained in vivo from the human brain, in order to get information clinically useful for the study and diagnosis of brain tumors. Therefore, a literature-based study of the technique was made, including a review of the Physics
Publicado em: 2008