Methanol Recovery
Mostrando 1-12 de 76 artigos, teses e dissertações.
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1. HSCCC Separations of Rutin Esters Obtained by Enzymatic Reaction Catalyzed by Lipase
The flavonoid rutin presents several pharmacological effects, despite this, its application in the pharmaceutical industry can be significantly limited by its low bioavailability. The development of lipophilic derivatives by esterification of hydroxyl groups with fatty acid chains may be an effective strategy to change their physicochemical properties. This
J. Braz. Chem. Soc.. Publicado em: 2021-03
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2. Application of a New Validated HPLC-PDA Method for Simultaneous Determination of Curcumin and Melatonin in Hyaluronic Acid-Coated Nanoemulsions
In this study, a high-performance liquid chromatography with photodiode array detector (HPLC-PDA) method was developed and validated to simultaneously determine curcumin (CUR) and melatonin (MEL) in hyaluronic acid-coated nanoemulsions, a novel targetable delivery system to CD44 receptors overexpressed in many types of tumors. Chromatographic analyses were p
J. Braz. Chem. Soc.. Publicado em: 2020-03
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3. Simultaneous liquid chromatography- tandem mass spectrometry method to quantify epicatechin and procyanidin B2 in rat plasma after oral administration of Trichilia catigua (catuaba) extract and its application to a pharmacokinetic study
Abstract Trichilia catigua A. Juss., Meliaceae, known as catuaba in Brazil, is traditionally used for the treatment of stress, sexual impotence and memory deficits. To our knowledge, there is no analytical method described in literature for simultaneous quantification of catuaba extract marker substances in biological matrices. The aim of this study was to d
Rev. bras. farmacogn.. Publicado em: 17/10/2019
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4. Urea-based polymethacrylamide purification
ABSTRACT A purification procedure of polymethacrylamide (PMAm) based on the urea feature of being a powerful Hbond breaker is proposed here. Polymethacrylamide was synthesized in water and the final product presents itself as an insoluble gel what is an obstacle to purification. This physical gel, kept together by numerous interchain H-bonds between amide gr
Matéria (Rio J.). Publicado em: 16/09/2019
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5. A NEW VALIDATED METHOD FOR DETERMINATION OF ROFLUMILAST IN TABLET BY CZE-UV
This paper reports a new and validated capillary electrophoresis method to determine Roflumilast (RFL) with an internal standard in tablet. The separation was made on an uncoated fused-silica capillary column 50 cm effective length and 75 µm i.d. 20 mmol L-1 of Na2B4O7 buffer including 15% (v/v) methanol (pH=9.5) was used as background electrolyte. A potent
Quím. Nova. Publicado em: 18/07/2019
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6. Determination of methanol residues in crude glycerol for animal feed by gas chromatography
ABSTRACT: Crude glycerol is a major by-product of biodiesel production and is an economical additive feed for ruminants. However, residual methanol in crude glycerol can be harmful to animal health. Several methods exist for quantifying methanol residues in biodiesel, yet few have been described that identify the methanol level in crude glycerol. We propose
Sci. agric. (Piracicaba, Braz.). Publicado em: 30/05/2019
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7. Developed and validated stability indicating HPLC method for the determination of epirubicin in bulk drug, marketed injection and polymeric nanoparticles
Present work is aimed to develop a simple, sensitive, robust and reliable HPLC method for routine quality control of epirubicin (EPI) in bulk drug, marketed injections and polymeric nanoparticles. Separation was carried out by C18 column. Isocratic elution was carried out using mobile phase A: 0.16% o-phosphoric acid solution, B: acetonitrile and methanol mi
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
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8. New Method for Carotenoid Extraction and Analysis by HPLC-DAD-MS/MS in Freeze-Dried Citrus and Mango Pulps
Carotenoid analysis in citrus is still a challenge due to their complex carotenoid profile and matrix acidity, which can promote isomerization and epoxide-furanoid rearrangements of these compounds. A new method for carotenoid extraction from freeze-dried citrus was developed. Extraction was carried out by magnetic stirring using ethyl acetate and methanol a
J. Braz. Chem. Soc.. Publicado em: 2018-01
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9. An innovative, simple, fast, and less toxic high-performance liquid chromatographic method for determination of prednisone in capsules
ABSTRACT Prednisone is an anti-inflammatory steroid drug widely used in clinical practice. However, no high-performance liquid chromatographic (HPLC) method has been described in the literature for the determination of prednisone in capsules until now. Thus, an HPLC method was developed using a C18 (250x4.0, 5 µm) column, with methanol:water (70:30) as mobi
Braz. J. Pharm. Sci.. Publicado em: 22/06/2017
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10. A Simple and Fast Method for Magnetic Solid Phase Extraction of Ochratoxin A
We report on the synthesis of dopamine loaded magnetic nanoparticles (MNPs) for new, simple, fast and repeatable extraction of ochratoxin A from different solvents and milk without utilizing immunoaffinity columns and even high-tech devices. To this end, Fe3O4 nanoparticles (NPs) were synthesized using thermal decomposition reaction and dopamine (DPA) was th
J. Braz. Chem. Soc.. Publicado em: 2017-06
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11. Development and validation of alternative methods by non-aqueous acid-base titration and derivative ultraviolet spectrophotometry for quantification of sildenafil in raw material and tablets
Sildenafil citrate (SILC) is a potent phosphodiesterase-5 inhibitor used for erectile dysfunction and pulmonary hypertension. This study shows two simple, fast and alternative analytical methods for SILC determination by non-aqueous titration and by derivative ultraviolet spectrophotometry (DUS) in active pharmaceutical ingredient and/or dosage forms. The qu
Braz. J. Pharm. Sci.. Publicado em: 20/04/2017
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12. Pesticide Residues Method Validation by UPLC-MS/MS for Accreditation Purposes
The development and validation of an analytical method for the determination of 51 pesticides in tomato using UPLC-MS/MS (ultra performance liquid chromatography coupled to tandem mass spectrometry) was performed in order to fulfill the requirements of the NBR ISO/IEC 17025:2005. The goal of the validation was to evaluate all required parameters, such as lin
J. Braz. Chem. Soc.. Publicado em: 2016-06