Mixture Planning
Mostrando 1-12 de 21 artigos, teses e dissertações.
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1. Surveillance of antiviral resistance markers in Argentina: detection of E119V neuraminidase mutation in a post-treatment immunocompromised patient
Although vaccines are the best means of protection against influenza, neuraminidase inhibitors are currently the main antiviral treatment available to control severe influenza cases. One of the most frequent substitutions in the neuraminidase (NA) protein of influenza A(H3N2) viruses during or soon after oseltamivir administration is E119V mutation. We descr
Mem. Inst. Oswaldo Cruz. Publicado em: 16/11/2016
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2. Modelos ridge em planejamentos de misturas: uma aplicação na extração da polpa de pequi
Mixture Models can be used in experimental situations involving areas related to food science and chemistry. Some problems of a statistical nature can be found, such as effects of multicollinearity that result in uncertainty in the optimization of a dependent variable. This study proposes the application of the ridge model adapted for mixture planning consid
Quím. Nova. Publicado em: 2013
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3. Use of experimental design for the development of chromatographic methods in the pharmaceutical industry / Emprego de planejamento experimental no desenvolvimento de métodos cromatográficos na indústria farmacêutica
O objetivo deste trabalho foi utilizar técnicas de planejamento experimental durante o desenvolvimento e validação de métodos de cromatografia liquida de alta eficiência (CLAE), para análise de medicamentos na indústria farmacêutica, a fim de demonstrar sua aplicabilidade e as vantagens de sua utilização. Uma avaliação multivariada da robustez do
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/11/2012
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4. Simultaneous determination of pesticides used electroanalytical methods and chemometri methods / Determinação simultanêa de pesticidas utilizando métodos eletroanalíticos e quimiométricos
This paper describes the simultaneous determination of the pesticides paraquat and diquat using electroanalytical techniques coupled with chemometric methods. Although these two pesticides can be easily determined in trace levels, the same does not apply to mix due to a large overlap of the voltammetric peaks. For this reason it became necessary to treat the
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/03/2011
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5. Estudo experimental das solubilidades de alguns ácidos em misturas hidro-alcoólicas
Solubility data of chemistry compounds in water and in solvent mixtures are fundamental in the project of separation industrial equipments, such as: crystallizers, extractors, evaporators, leachates and absorption units. The accuracy that it is obtained in projects of chemistry industry equipment is closely related with the quality of experimental data used
Publicado em: 2010
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6. Espumantes de maçã obtidos pelos processos ASTI, Charmat e Champenoise / Espumantes de maçã obtidos pelos processos ASTI, Charmat e Champenoise
The use of musts made with apples discarded during classification to in natura trade and the artificial gasification of the fermented, undertake the quality of Brazilian cider. The fermentation process used results in carbon dioxide loss and, consequently, aromatics compounds with large importance to the sensorial attributes of the fermented as well. The pro
Publicado em: 2009
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7. Optimization of controlled release primaquine diphosphate tablets / Otimização da liberação de difosfato de primaquina em comprimidos de liberação controlada
The objective of the present work was to produce primaquine diphosphate controlled release tablets based on hydrophilic polymers and use the mixture statistical experimental design (DOE) to optimize drug release. In selecting the components of the formulations, differential scanning calorimetry (DSC) were carried out to verify the compatibility between drug/
Publicado em: 2009
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8. Adequacy of cytogenetic dosimetry to evaluate partial and total body irradiation / AdequaÃÃo da dosimetria citogenÃtica para avaliaÃÃo de irradiaÃÃo parcial e de corpo inteiro
The majority of human exposures to ionizing radiation involves partial human body irradiation. Thus, the use of cytogenetic dosimetry, when this aspect is not taken into account, can result in dose underestimation to the irradiated subject. In this context, this research studied methodological parameters of biodosimetry, such as cell culture time, time of Co
Publicado em: 2009
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9. Study of partition of ovomucoid protein in aqueous twophase systems and anionic or hydrophobic resins / Estudo da partição da proteína ovomucoide em sistemas aquosos bifásicos e em resinas aniônica ou hidrofóbica
In this work, the application of the liquid-liquid extraction technique with aqueous two-phase systems (ATPS) was evaluated for the separation of ovomucoid, an egg white protein. This technique is an advisable purification process applied to large scale since it provides a selective partition with high yields. The ATPS were composed by PEG 1500 and an inorga
Publicado em: 2009
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10. Hidrólise ácida e retirada de sais da glicerina bruta proveniente da produção de biodiesel. / Acid hydrolysis and salts extraction of raw glycerin from biodiesel production.
Este trabalho tem como objetivo otimizar as etapas da rota de purificação da glicerina bruta proveniente da produção de biodiesel, sendo elas, hidrólise ácida e retirada de sais através dos processos utilizando o efeito salting-out e troca iônica até obter uma solução aquosa de glicerol e etanol. Foi feito um planejamento fatorial 22 com dois pont
Publicado em: 2009
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11. AVALIAÇÃO MERCADOLÓGICA E DE PRODUÇÃO AGRÍCOLA, VISANDO A PROPOSIÇÃO DE SISTEMAS AGROFLORESTAIS PARA A MESORREGIÃO SUDOESTE DE MATO GROSSO DO SUL / MERCADOLÓGICA EVALUATION IN AGRICULTURAL PRODUCTION, VISANDO A PROPOSAL FOR SAF FOR MESORREGIÃO SOUTHEST MATO GROSSO IN SOUTH
The present work was perceived in municipal district of Dourados/MS, mesoregion southwest of Mato Grosso do Sul, with he purpose of meeting the socio-demographic profile and the habits of consumers shopping of fruits and vegetables, and obtain social indications and agroeclogical develop models for planning of production systems based on agroforestry sistems
Publicado em: 2009
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12. SÃntese de Derivados de Vitamina A utilizando Lipase de Candida antartica Imobilizada (Novozyme 435) / Vitamin A derivatives synthesis using immobilized lipase from Candida antarctica (Novozyme 435)
The main objective of this work was to synthesize vitamin A derivatives through an enzymatic route, as an alternative to chemistry route, more aggressive to the environment. The conversion of retinyl acetate into retinyl palmitate would result in a product with better market acceptance, since it is more stable than the ester used as substrate. Retinyl adipat
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/08/2007