Modulators
Mostrando 1-12 de 445 artigos, teses e dissertações.
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1. Devemos orientar a redução do consumo de alimentos ricos em vitamina K para pacientes anticoagulados em uso de varfarina?
A varfarina produz seu efeito anticoagulante inibindo o ciclo de conversão da vitamina K e, dessa forma, impedindo a ação biológica dos fatores da coagulação vitamina K-dependentes. O consumo de alimentos contendo vitamina K, portanto, interfere no efeito anticoagulante da varfarina. Entretanto, é inadequado orientar os pacientes a diminuir o consu
Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023
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2. BMP-4, TGF-β and Smad3 as Modulators of Synovial Fluid Cells Viability
Resumo Objetivo Nosso objetivo foi avaliar a modulação das células do líquido sinovial (SFCs, na sigla em inglês) de pacientes com e sem osteoartrite (OA) por proteína morfogenética óssea 4 (BMP-4), Smad3 e transformador do fator de crescimento β (TGF-β). Métodos O do líquido sinovial foi coletado de pacientes submetidos a artroscopia ou artrop
Revista Brasileira de Ortopedia. Publicado em: 2022
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3. Omega 3 fatty acids - Potential modulators for oxidative stress and inflammation in the management of sickle cell disease
Abstract Objective Sickle cell disease is characterized by clinical complications resulting in vaso-occlusive crisis with prominent attributes of oxidative stress, inflammation, and pain. Inflammation is an integral part of this disease which further exacerbates the pain during a crisis. Omega-3 fatty acids are known to possess anti-inflammatory and anti-ag
Jornal de Pediatria. Publicado em: 2022
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4. Host response and peri-implantitis
Abstract Considering the absence of predictable and effective therapeutic interventions for the treatment of peri-implantitis, scientific evidence concerning the host response profile around dental implants could be important for providing in the future a wider preventive and/or therapeutic window for this peri-implant lesion, indicating biomarkers that prov
Braz. oral res.. Publicado em: 30/09/2019
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5. Mechanisms and biomarker candidates in pterygium development
RESUMO A patogênese do pterígio tem sido relacionada, prin cipalmente, à exposição à luz ultravioleta, mas esta asso ciação permanece bastante controversa. O mecanismo completo do pte rígio também permanece por esclarecer. Fatores como inflamação, infecção viral, estresse oxidativo, metilação do DNA, mediadores inflamatórios, moduladores de
Arq. Bras. Oftalmol.. Publicado em: 30/09/2019
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6. Sweeteners and sweet taste enhancers in the food industry
Abstract The search for new sweeteners technologies has increased substantially in the past decades as the number of diseases related to the excessive consumption of sugar became a public health concern. Low carbohydrates diets help to reduce ingested calories and to maintain a healthy weight. Most natural and synthetic high potency non-caloric sweeteners,
Food Sci. Technol. Publicado em: 16/04/2018
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7. Antimicrobial activity and acetylcholinesterase inhibition by extracts from chromatin modulated fungi
ABSTRACT Major health challenges as the increasing number of cases of infections by antibiotic multiresistant microorganisms and cases of Alzheimer's disease have led to searching new control drugs. The present study aims to verify a new way of obtaining bioactive extracts from filamentous fungi with potential antimicrobial and acetylcholinesterase inhibitor
Braz. J. Microbiol.. Publicado em: 2018-03
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8. Actiflagelin, a new sperm activator isolated from Walterinnesia aegyptia venom using phenotypic screening
Abstract Background Sperm contains a wealth of cell surface receptors and ion channels that are required for most of its basic functions such as motility and acrosome reaction. Conversely, animal venoms are enriched in bioactive compounds that primarily target those ion channels and cell surface receptors. We hypothesized, therefore, that animal venoms shou
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 22/02/2018
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9. An Analytical Solution for Fiber Optic Links with Photonic-Assisted Millimeter Wave Upconversion Due to MZM Nonlinearities
Abstract Photonic-assisted technique employed in the generation of stable and high-purity signals in the millimeter wave band has been investigated using dual-parallel Mach-Zehnder modulator. Indeed, this type of generation performs a high order RF multiplier, whose operation principle steams out from the nonlinear characteristic of the external modulators.
J. Microw. Optoelectron. Electromagn. Appl.. Publicado em: 2017-03
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10. ESTRATÉGIAS DE SÍNTESE NA DESCOBERTA DE FÁRMACOS: O EMPREGO DA SÍNTESE ORIENTADA PELA DIVERSIDADE ESTRUTURAL
Drug discovery often involves screening synthetic small molecules for their ability to bind to a macromolecular target. Target-Oriented Synthesis of a specific compound or a focused library can be planned combining retrosynthetic analysis and rational drug design. Biologically active molecules also can be identified through the unfocused screening of compoun
Quím. Nova. Publicado em: 2016-09
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11. Incidence of virulence determinants in clinical Enterococcus faecalis and Enterococcus faecium isolates collected in Bulgaria
Abstract Objectives To evaluate the prevalence of some virulence genes among 510 clinical Enterococcus spp. isolates and to assess the association of those genes with the species, infection site, and patient group (inpatients/outpatients). Methods Adhesins genes (aggregation substances agg and asa1 of Enterococcus faecalis and Enterococcus faecium, respect
Braz J Infect Dis. Publicado em: 2016-04
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12. Farmacogenética dos moduladores do metabolismo cerebrovascular na síndrome demencial da doença de Alzheimer
The aims of this study were to investigate risk factors for cognitive and functional decline among 193 patients with Alzheimer’s disease dementia (AD), and to conduct pharmacogenetic analysis on cerebrovascular metabolism modulators, taking into account APOE haplotypes and the genotypes of ACE, CETP, LDLR and the LXR-β gene. For all patients, later age at
Arq. Neuro-Psiquiatr.. Publicado em: 2015-03