Monensin Toxicity
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Intoxicação por monensina em búfalos. / Monensin toxicosis in water buffaloes
O primeiro artigo desse estudo apresenta a ocorrência de um surto de intoxicação por monensina em búfalos de um rebanho misto com bovinos, os quais não foram afetados. Tal fato sugeriu a possibilidade de que búfalos fossem menos tolerantes à monensina que bovinos. Embora com número reduzido de animais experimentais, dados preliminares foram compatív
Publicado em: 2007
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2. Processing of the structural proteins of human immunodeficiency virus type 1 in the presence of monensin and cerulenin.
The synthesis and processing of structural proteins of human immunodeficiency virus type 1 (HIV-1) were studied in infected cells treated with monensin and cerulenin. In MOLT-3 cells chronically infected with HTLV-IIIB, monensin inhibited the proteolytic cleavage of the env-coded polyprotein gp160 to gp120, leading to the accumulation of the precursor gp160.
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3. Role of a low-pH environment in adenovirus enhancement of the toxicity of a Pseudomonas exotoxin-epidermal growth factor conjugate.
A conjugate of Pseudomonas exotoxin and epidermal growth factor (PE-EGF) inhibits proteins synthesis in KB cells, and this inhibition is increased by adenovirus. Protein synthesis inhibition is dependent on the amount of adenovirus and PE-EGF used and the time of incubation of cells with these agents. With 1 microgram of adenovirus and 0.5 micrograms of PE-E
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4. Characterization of the potent in vitro and in vivo antimalarial activities of ionophore compounds.
Large-scale in vitro screening of different types of ionophores previously pinpointed nine compounds that were very active and selective in vitro against Plasmodium falciparum; their in vitro and in vivo antimalarial effects were further studied. Addition of the ionophores to synchronized P. falciparum suspensions revealed that all P. falciparum stages were