N Myc Downregulated Gene 1
Mostrando 1-3 de 3 artigos, teses e dissertações.
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1. Estudo dos genes NDRG1, Par-4, osteonectina e pontina, em tecido mamário hiperplásico através de técnica de imunohistoquímica / Study of NDRG1, Par-4, osteonectin and pontin expression in hyperplastic breast lesions with immunohistochemical technique
INTRODUCTION: Breast cancer is a leading cause of death among women all over the Word. Proliferative lesions of the breast are believed to be precursors of or markers of increased risk for breast carcinoma. Although the active research in the field of breast cancer, the early molecular events associated with cancer evolution and progression are still poorly
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/05/2011
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2. Differential regulation of the N-myc proto-oncogene by ROR alpha and RVR, two orphan members of the superfamily of nuclear hormone receptors.
ROR alpha1 and RVR are orphan members of the superfamily of nuclear hormone receptors which constitutively activate and repress, respectively, gene transcription by binding to a common DNA sequence. In an attempt to understand the physiological functions of these two transcription factors, we aimed to identify target genes. We have identified a consensus bin
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3. Positive and negative regulation of EAAT2 by NF-κB: a role for N-myc in TNFα-controlled repression
The glutamate transporter gene, EAAT2/GLT-1, is induced by epidermal growth factor (EGF) and downregulated by tumor necrosis factor α (TNFα). While TNFα is generally recognized as a positive regulator of NF-κB-dependent gene expression, its ability to control transcriptional repression is not well characterized. Additionally, the regulation of NF-κB by