Neonate Rats
Mostrando 1-12 de 27 artigos, teses e dissertações.
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1. Ventilation-induced changes correlate to pulmonary vascular response and VEGF, VEGFR-1/2, and eNOS expression in the rat model of postnatal hypoxia
Neonatal asphyxia occurs due to reduction in oxygen supply to vital organs in the newborn. Rapid restoration of oxygen to the lungs after a long period of asphyxia can cause lung injury and decline of respiratory function, which result from the activity of molecules that induce vascular changes in the lung such as nitric oxide (NO) and vascular endothelial g
Braz J Med Biol Res. Publicado em: 08/10/2018
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2. Brain caspase-3 and intestinal FABP responses in preterm and term rats submitted to birth asphyxia
Neonatal asphyxia can cause irreversible injury of multiple organs resulting in hypoxic-ischemic encephalopathy and necrotizing enterocolitis (NEC). This injury is dependent on time, severity, and gestational age, once the preterm babies need ventilator support. Our aim was to assess the different brain and intestinal effects of ischemia and reperfusion in n
Braz J Med Biol Res. Publicado em: 23/06/2016
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3. Efeitos da administração de melatonina sobre o metabolismo energetico e fosforilação de proteinas sinalizadoras no hipotalamo de ratos neonatos / Effects of melatonin administration on energy metabolism and protein phosphorylation in the hypothalamus of neonatal rats
A melatonina (MLT) é um neurohormônio presente em humanos e outros vertebrados, sendo a glândula pineal principal fonte produtora. Além de sua conhecida ação cronobiológica, a MLT tem papel regulador sobre o metabolismo energético e sobre a massa corporal de mamíferos. A presença de receptores para MLT nos núcleos hipotalâmicos dorso-medial, supr
Publicado em: 2009
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4. Comparative proteome of rat s spinal cord submitted to a peripheral nerve injury in postnatal period / Proteoma comparativo da medula espinhal lombar de ratos submetidos a lesão nervosa periferica durante o periodo pos-natal
Neurotraumas periféricos, situação recorrente atualmente na humanidade, resultam em reorganizações e modificações tanto do sistema nervoso periférico que foi lesado quanto do sistema nervoso central, mais especificamente da medula espinhal na tentativa de reparar o dano gerado. O período pós-natal apresenta intensa plasticidade neuronal medular já
Publicado em: 2009
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5. Imprinting estrogenico : efeito sobre a expressão do receptor de androgeno no hipotalamo de ratos Wistar / Effects of estrogenic imprinting on the androgen receptor expression in the hypothalamus of Wistar rats
In male rats, complete reproductive function is critically dependent on adequate estrogen action at different levels of the hypothalamic-pituitary-gonadal axis. The administration of high doses during the period of sexual differentiation results in irreversible alterati ns in the male reproductive system. In brief, the estrogens have anti-androgenic effects
Publicado em: 2008
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6. Maturation of the secretory response to glucose by INGAP (Islet Neongenesis Associated Protein) in islets of Langerhans of neonatal rats / Maturação da resposta secretoria a glicose pelo INGAP (Islet Neongenesis Associated Protein) em ilhotas de Langerhans de ratos neonatos
The Islet Neogenesis Associated Protein (INGAP) increases pancreatic ß-cell mass and potentiates glucose-induced insulin secretion. Here, we have studied the effects of the pentadecapeptide having the 104-118 amino acid sequence of INGAP (INGAP-PP) on the expression of genes related to the pancreatic islets, the expression and phosphorylation of components
Publicado em: 2008
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7. Modulation of the defense mechanism of pancreatic islets against oxidative stress / Modulação dos mecanismo de defesa das ilhotas pancreaticas contra o estresse oxidativo
No diabetes mellitus, radicais de oxigênio estão associados com perda de sensibilidade à glicose ou destruição das células b. Nesse trabalho, investigamos a tolerância de ilhotas de Langerhans de ratos neonatos ao estresse provocado por H2O2, seus mecanismos antioxidantes de defesa e os fatores que promovem manutenção da sensibilidade à glicose. Cu
Publicado em: 2006
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8. Neonatal administration of citalopram delays somatic maturation in rats
We investigated the somatic maturation of neonate rats treated during the suckling period with citalopram, a selective serotonin reuptake inhibitor. Groups with 6 male neonates were randomly assigned to different treatments 24 h after birth. Each litter was suckled by one of the dams until the 21st postnatal day. Body weight, head axis and tail length were m
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-10
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9. A Glycoconjugate Vaccine for Neisseria meningitidis Induces Antibodies in Human Infants That Afford Protection against Meningococcal Bacteremia in a Neonate Rat Challenge Model
The functional activities of serum samples from human infants immunized with a glycoconjugate vaccine for Neisseria meningitidis serogroup C were assessed in a complement-mediated antibody-dependent serum bactericidal assay (SBA) and in a neonate rat model of protection from bacteremia. Selective serum samples from individual human infants were combined to m
American Society for Microbiology.
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10. Mycoplasma-induced hydrocephalus in rats and hamsters.
Mycoplasma pulmonis, a pathogen of the respiratory tract in rats, was inoculated intracerebrally into neonate rats and hamsters to determine if it would induce lesions in the ependyma. Hydrocephalus was induced in 116 of 120 rats and in 23 of 28 hamsters. The severity of hydrocephalus was greater in the rats than in the hamsters. Hydrocephalus induction occu
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11. Toxicity of group B Streptococcus agalactiae in adult rats.
Several strains of group B Streptococcus agalactiae were found to be lethal for young adult rats. When bacteria were heat killed and then injected intraperitoneally into rats, rapid death (14 to 18 h) of the rats occurred, characterized by labored breathing, hemolyzed serum, hemoglobinuria, and subungual hemorrhages. Sections of tissues from these rats faile
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12. Zinc-binding ligands in milk and intestine: a role in neonatal nutrition?
The hypothesis that a zinc-binding ligand (ZBL) recently discovered in human milk but absent from cow's milk might be related to zinc nutrition in the neonate was investigated. The zinc-binding characteristics of rat milk were examined to determine if the rat was a suitable model. By gel filtration, rat milk was found to contain a ZBL with characteristics si