Neural Tube Defects
Mostrando 1-12 de 171 artigos, teses e dissertações.
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1. Glycemic and nonglycemic mechanisms of congenital malformations in hyperglycemic pregnancies: a narrative review
ABSTRACT Congenital malformations are more frequently found among children born to mothers with diabetes than in the background population. There are several complex mechanisms involved in the development of congenital malformations in the offspring of mothers with hyperglycemia, such as the overexpression of glucose transporters (GLUTs) 1 and 2, the increas
Archives of Endocrinology and Metabolism. Publicado em: 2022
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2. [PROVISIONAL] Birth defects in Brazil: Outcomes of a population-based study
Abstract Birth defects (BDs) are functional and structural alterations in embryonic or fetal development. With an incidence of approximately 3-5%, BDs are a leading cause of infant mortality and lifelong disability. A population-based prospective case-control study was conducted for one year with 5204 infants, between 1st March 2011 and 29th February 2012, i
Genet. Mol. Biol.. Publicado em: 12/08/2019
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3. Folate and Cancer: Is There Any Association?
Abstract Folate plays a central role in DNA synthesis and methylation, which are essential for DNA integrity maintenance and gene expression. Folate deficiency may lead to the incorporation of uracil into DNA and chromosome breaks, increasing the risk of cancer. However, conflicting evidence has been observed depending on the type of epidemiological study, d
J. inborn errors metab. screen.. Publicado em: 30/05/2019
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4. Congenital hemangioma in spondylocostal dysostosis: a novel association
Abstract Congenital hemangioma is a benign tumor caused by dysfunction in embryogenesis and vasculogenesis, which progresses during fetal life to manifest as fully developed at birth. Although hemangiomas are the most common tumor of infancy, rapidly involuting congenital hemangioma has not been described in spondylocostal dysostosis. I report the novel asso
An. Bras. Dermatol.. Publicado em: 2016-10
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5. Treatment of infertility in women with polycystic ovary syndrome: approach to clinical practice
Polycystic ovary syndrome represents 80% of anovulatory infertility cases. Treatment initially includes preconception guidelines, such as lifestyle changes (weight loss), folic acid therapy to prevent the risk of fetal neural tube defects and halting the consumption of tobacco and alcohol. The first-line pharmacological treatment for inducing ovulation consi
Clinics. Publicado em: 2015-11
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6. Defectos del tubo neural y del ácido fólico: recorrido histórico de una intervención preventiva altamente efectiva
This article gives a broad overview of part of the historical evolution of medical knowledge about neural tube defects (NTD) and the discovery of vitamin B9 or folic acid, as well as some relevant research events that, over the course of several centuries, defined the relationships between the understanding of central nervous system embryology, the discovery
Hist. cienc. saude-Manguinhos. Publicado em: 16/01/2015
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7. Concentrations of blood folate in Brazilian studies prior to and after fortification of wheat and cornmeal (maize flour) with folic acid: a review
BACKGROUND: In July 2004, the Brazilian Ministry of Health through the National Health Surveillance Agency made the fortification of wheat flour and cornmeal (maize flour) with iron and folic acid mandatory, with the intention of reducing the rate of diseases such as neural tube defects. OBJECTIVE: The aim of the study was to investigate the impact of
Rev. Bras. Hematol. Hemoter.. Publicado em: 2014-07
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8. Prevalência de defeitos do tubo neural no estado de São Paulo antes e após a fortificação das farinhas com ácido fólico / Prevalence of neural tube defects in the state of Sao Paulo before and after fortification of flour with folic acid
Introdução: Defeitos do tubo neural (DTN) são as malformações mais freqüentes do sistema nervoso. Decorrem de falha no fechamento do tubo neural embrionário entre 21-28 dias após a concepção e representam importante causa de morbimortalidade infantil passível de prevenção. Os defeitos mais freqüentes são anencefalia e espinha bífida. Consider
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/12/2011
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9. PERFIL EPIDEMIOLÓGICO E NÍVEL SÉRICO DE ÁCIDO FÓLICO EM MÃES DE CRIANÇAS PORTADORAS DE DEFEITO DO TUBO NEURAL. / EPIDEMIOLOGICAL PROFILE AND SERUM FOLATE IN MOTHERS OF CHILDREN WITH NEURAL TUBE DEFECT.
O defeito do tubo neural (DTN), que é uma malformação congênita, participa de modo considerável nas estatísticas de morbidade e mortalidade perinatais devido a suas elevadas taxas de incidência. Os DTN, podem se limitar ao sistema nervoso central e/ou periférico, e também podem incluir os tecidos sobrejacentes (ossos, músculos e tecido conjuntivo).
Publicado em: 2011
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10. Consumo habitual de alimentos ricos em folato como um possível fator de proteção para a Síndrome de Down
Objetivo: Verificar se há diferença entre o consumo habitual de folato entre mães de crianças com Síndrome de Down e mães de crianças sem malformações. Métodos: Foi realizado um estudo de caso-controle, com um total de 100 mães das quais 50, incluídas no grupo caso, apresentavam filhos com Síndrome de Down e 50, consideradas grupo controle,tinha
Publicado em: 2011
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11. Health-related quality of life of children and adolescents with meylomeningocele / Qualidade de vida relacionada à saúde em crianças e adolescentes com mielomeningocele
Myelomenigocele (MM) is the most common and disabling disorder of neural tube defects. It is associated to several health problems and to motor and sensitive disabilities. This condition may impair patients health-related quality of life (HRQL). However, it is not established how different neurological lesion levels and functional ambulation influence HRQL.
Publicado em: 2009
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12. Evaluation of congenital malformation risks in newborn babies whose mothers has been exposed to thihalometanes / Avaliação do risco de malformação congênita em recém-nascidos de mães expostas ao trihalometano
Este estudo tratou de avaliar possíveis efeitos a saúde de recémnascidos cujas mães foram expostas ao trihalometanos (THM) contidos nas água de abastecimento público da cidade de São Paulo. O processo de tratamento da água de abastecimento utilizado no Brasil envolve uma etapa de desinfecção cujo objetivo é eliminar microorganismos patogênicos pr
Publicado em: 2009