Neurobehavioral Effects
Mostrando 1-12 de 22 artigos, teses e dissertações.
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1. Effects of carvacrol and physical exercise on motor and memory impairments associated with Parkinson’s disease
RESUMO O presente estudo foi realizado para investigar os efeitos do carvacrol e do exercício em esteira sobre o déficit de memória, comportamento rotacional e biomarcadores de estresse oxidativo em um modelo animal (ratos lesionados por 6-OHDA) da doença de Parkinson (DP). Ratos Wistar foram tratados com carvacrol na dose de 25 mg/kg e/ou correram em um
Arq. Neuro-Psiquiatr.. Publicado em: 29/07/2019
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2. Protective effect and mechanism of Lactobacillus on cerebral ischemia reperfusion injury in rats
The present study was designed to investigate the protective effects and mechanism of inactivated lactobacillus (ILA) on cerebral ischemia reperfusion injury (CIRI) in rats. In this experiment, 30 male Sprague Dawley rats were randomly divided into control group, IRI groups, and ILA group. A middle cerebral artery occlusion and reperfusion model was prepared
Braz J Med Biol Res. Publicado em: 17/05/2018
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3. Neuropharmacological and genotoxic evaluation of ethanol extract from Erythrina falcata leaves, a plant used in Brazilian folk medicine
The aim of the present study was to determine neurobehavioral and genotoxic activities of ethanol extract of Erythrina falcata Benth., Fabaceae, leaves on rats. Animals were treated with ethanol extract of E. falcata (100, 300 or 500 mg/kg; i.p.) and the open field and elevated plus-maze tasks were used as behavioral models to investigate a possible effect o
Rev. bras. farmacogn.. Publicado em: 25/02/2013
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4. Efeitos neurocomportamentais e neuroquÃmicos da clorpromazina e clozapina no modelo de esquizofrenia induzido pela cetamina em camundongos. / Neurobehavioral and neurochemical effects of chlorpromazine and clozapine in the model of schizophrenia induced by ketamine in mice.
A esquizofrenia à um transtorno mental crÃnico, grave e incapacitante que afeta cerca de 1% da populaÃÃo mundial, cujos sintomas podem ser induzidos pela Cetamina. Neste sentido, hà evidÃncias de que o estresse oxidativo tenha importante papel na patogÃnese desta doenÃa. Desta forma, o presente estudo avaliou os efeitos neurocomportamentais e neuroqu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/05/2011
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5. Neurobehavioral, reflexological and physical development of Wistar rat offspring exposed to ayahuasca during pregnancy and lactation
Ayahuasca is a hallucinogenic beverage prepared by the decoction of plants native to the Amazon Basin region. The beverage has been used throughout the world by members of some syncretic religious movements. Despite the recent legalization of ayahuasca in Brazil for religious purposes, there is little pre-clinical and clinical information attesting to its sa
Revista Brasileira de Farmacognosia. Publicado em: 16/09/2011
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6. Prenatal tobacco exposure is related to neurobehavioral modifications in infants of adolescent mothers
INTRODUCTION: Prenatal tobacco exposure interferes with neonatal outcomes. OBJECTIVE: To determine the neonatal neurobehavioral effects of in utero tobacco exposure. METHODS: This prospective cross-sectional study included healthy, term, with birth weight appropriate for gestacional age neonates without exposure to alcohol, drugs, or infections, born to adol
Clinics. Publicado em: 2011
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7. Aspectos da exposição ambiental aos agroquímicos no desenvolvimento animal.
A busca de indicadores da exposição de organismos não-alvo a agroquímicos vem cada vez mais se intensificando. As alterações neurocomportamentais estão entre as medidas de eventos biológicos estudadas como possíveis indicadores da exposição a tais substâncias. Entretanto, muitos dos agroquímicos aplicados corriqueiramente em nossa agricultura n�
Cadernos de Ciência & Tecnologia. Publicado em: 2011
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8. Genotoxic, neurotoxic and neuroprotective activities of apomorphine and its oxidized derivative 8-oxo-apomorphine
Apomorphine is a dopamine receptor agonist proposed to be a neuroprotective agent in the treatment of patients with Parkinson’s disease. Both in vivo and in vitro studies have shown that apomorphine displays both antioxidant and pro-oxidant actions, and might have either neuroprotective or neurotoxic effects on the central nervous system. Some of the neuro
Publicado em: 2010
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9. Avaliação da toxicidade da Ipomoea carnea em caprinos durante o período perinatal: estudos de neuroteratologia / Evaluation of the toxicity of Ipomoea carnea in goats during postnatal period
Ipomoea carnea, a shrub plant, is a toxic plant largely distributed throughout Brazil and others topical countries. This plant possess swainsonine, an indolizidinic alkaloid as the most important active toxic principle, which promotes cellular accumulation of not metabolized oligossacarides, due to inhibition of acid or lisossomal αmanosidasis enzyme,
Publicado em: 2009
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10. Neurobehavioral effects of fipronil long term exposure in rats / Efeitos neurocomportamentais da exposição prolongada de ratos ao fibronil
Fipronil is a phenylpyrazole insecticide with broad spectrum, developed to selectively inhibit insect GABA-gated chloride channels; both in Veterinary Medicine, and in Agriculture it has been used for the control of nuisances. Although several studies try to understand the mechanism of neuronal toxicity of pesticide in mammalian, there are few studies relate
Publicado em: 2009
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11. O COMPLEXO METILMERCÚRIO-CISTEÍNA ALTERA O ACÚMULO DE MERCÚRIO EM DIFERENTES TECIDOS DE CAMUNDONGO / COMPLEX METHILMERCURY CYSTEINE ALTERS MERCURY ACCUMULATION IN DIFFERENT TISSUES OF MICE
Methylmercury (MeHg) is related to several deleterious effects on the vertebrate tissues, mainly on central nervous system, and part of these effects are through of interaction with sulfhydryl group found in cellular proteins. MeHg interacts with low and high molecular weight thiols in the blood and tissues and this fact, in some cases will allow a better ab
Publicado em: 2009
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12. Rotational behavior in free-swimming test as a modern model for the study of neurobehavioral effects of subchronic lead exposure during adult life / Comportamento rotacional em Teste de Nado Livre como um modelo em roedores para estudo da neurotoxicidade do chumbo durante a vida adulta
A exposição ao chumbo ainda permanece como um sério problema de saúde pública, especialmente nos países em desenvolvimento como o Brasil. Apesar do número crescente de estudos mostrando déficits neurocomportamentais em indivíduos expostos ocupacionalmente ao chumbo, os mecanismos envolvidos com a manifestação destes transtornos permanecem pouco co
Publicado em: 2009