Neurochemical Plasticity
Mostrando 1-3 de 3 artigos, teses e dissertações.
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1. Inoculação de células de Schwann cultivadas pré-tratadas ou não com as citocinas inflamatórias TGF-beta1 e TN- alfa; na medula espinal contusa de ratos. Análise neuroquímica da plasticidade medular / Inoculation of cultivated cells of Schwann daily pay-treated or not with the inflammatory cytokines TGF-beta1 and TNFalfa in the Spinal cord injuries of rats. Neurochemical analysis of the spinal cord plasticity
The experimental use of Schwann cells is indicated on spinal cord treatment due to the ability of these cells to produce neurotrophic factors and inflammatory cytokines, influencing nervous system environment. Male rats were submitted to a moderate spinal cord contusion (25mm) at 11th thoracic level. Culture Schwann cells were obtained from sciatic nerves an
Publicado em: 2008
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2. Transcriptional and posttranslational plasticity and the generation of inflammatory pain
Inflammatory pain manifests as spontaneous pain and pain hypersensitivity. Spontaneous pain reflects direct activation of specific receptors on nociceptor terminals by inflammatory mediators. Pain hypersensitivity is the consequence of early posttranslational changes, both in the peripheral terminals of the nociceptor and in dorsal horn neurons, as well
The National Academy of Sciences.
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3. Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine
Stress-induced structural remodeling in the adult hippocampus, involving debranching and shortening of dendrites and suppression of neurogenesis, provides a cellular basis for understanding the impairment of neural plasticity in the human hippocampus in depressive illness. Accordingly, reversal of structural remodeling may be a desirable goal for antidepress
The National Academy of Sciences.