Neuromuscular Blockade
Mostrando 1-12 de 75 artigos, teses e dissertações.
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1. Sugammadex administration in pregnant patients undergoing non-obstetric surgery: a case series
Abstract The use of sugammadex for reversal of rocuronium-induced neuromuscular blockade after caesarean section is nowadays common practice, but concerns exist about its use in pregnant women undergoing non-obstetric surgery. We report six cases of pregnant women submitted to general anesthesia for non-obstetric surgery in which neuromuscular blockade was r
Brazilian Journal of Anesthesiology. Publicado em: 2022
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2. Local and systemic effects caused by Crotalus durissus terrificus, Crotalus durissus collilineatus, and Crotalus durissus cascavella snake venoms in swiss mice
Abstract INTRODUCTION: Crotalus envenomations cause serious complications and can be fatal without appropriate treatment. Venom isoforms present and inter/intraspecific variations in the venom composition can result in different symptoms presented by bites by snakes from the same species but from different geographical regions. We comparatively evaluated th
Rev. Soc. Bras. Med. Trop.. Publicado em: 05/09/2019
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3. Severe bradycardia and asystole associated with sugammadex: case report
Resumo Justificativa e objetivos: O sugamadex é uma gama ciclodextrina modificada, o primeiro agente seletivo para reversão do bloqueio neuromuscular induzido pelos relaxantes musculares não despolarizantes do tipo esteroide, com maior afinidade para o rocurônio. Neste artigo apresentamos um caso de bradicardia grave e assistolia após administração d
Rev. Bras. Anestesiol.. Publicado em: 25/04/2019
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4. Patients with severe accidental tetanus admitted to an intensive care unit in Northeastern Brazil: clinical–epidemiological profile and risk factors for mortality
Abstract Introduction Tetanus, an acute infectious disease, is highly prevalent worldwide, especially in developing countries. Due to respiratory failure and hemodynamic instability associated with dysautonomia, severe cases require intensive care, but little has been published regarding the management in the Intensive Care Unit. Objective To draw a 10-yea
Braz J Infect Dis. Publicado em: 2016-10
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5. Association between levobupivacaine and pancuronium. Interference in neuromuscular transmission and blockade in rats
ABSTRACT PURPOSE: To evaluate the effects of levobupivacaine on neuromuscular transmission and neuromuscular blockade produced by pancuronium in vitro. METHODS: Thirty rats were distributed into groups (n = 5) according to the drug used alone or in combination: Group I - levobupivacaine (5 µg.mL-1); Group II - pancuronium (2 µg.mL-1); Group III - pancur
Acta Cir. Bras.. Publicado em: 2016-07
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6. Comparison of the variability of the onset and recovery from neuromuscular blockade with cisatracurium versus rocuronium in elderly patients under total intravenous anesthesia
This study was designed to compare the variability of the onset and offset of the effect of two neuromuscular blocking drugs with different elimination pathways in adult and elderly patients during total intravenous anesthesia (TIVA). After Ethics Committee approval and patients’ informed consent, the drugs were compared in 40 adult and 40 elderly patients
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-07
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7. Pharmacological and partial biochemical characterization of Bmaj-9 isolated from Bothrops marajoensis snake venom
Bmaj-9, a basic PLA2 (13679.33 Da), was isolated from Bothrops marajoensis snake venom through only one chromatographic step in reversed phase HPLC on ¼-Bondapak C-18 column. The amino acid composition showed that Bmaj-9 had a high content of Lys, His, and Arg, typical of a basic PLA2. The sequence of Bmaj-9 contains 124 amino acid residues with a pI value
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2012
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8. Estudo dos efeitos do veneno da serpente Bothrops alcatraz em preparações neuromusculares in vitro / Neuromuscular activity of Bothrops alcatraz snake venom in chick biventer cervcis preparations
Bothrops alcatraz é uma serpente do Arquipélago de Alcatrazes no litoral norte do estado de São Paulo, Brasil, recentemente descrita. Neste trabalho foram analisados os efeitos neuromusculares do veneno de B. alcatraz em preparações isoladas de biventer cervicis de pintainho (BC) e nervo frênico-diafragma de camundongo (NFD), sob estimulação elétric
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/08/2011
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9. Biochemical and genetic analysis of butyrylcholinesterase (BChE) in a family, due to prolonged neuromuscular blockade after the use of succinylcholine
Butyrylcholinesterase (BChE) is a plasma enzyme that catalyzes the hydrolysis of choline esters, including the muscle-relaxant succinylcholine and mivacurium. Patients who present sustained neuromuscular blockade after using succinylcholine usually carry BChE variants with reduced enzyme activity or an acquired BChE deficiency. We report here the molecular b
Genetics and Molecular Biology. Publicado em: 2011
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10. Mutagenicity induced by the hydroalcoholic extract of the medicinal plant Plathymenia reticulata Benth
Plathymenia reticulata Benth has an anti-inflammatory effect and is capable of neutralizing the neuromuscular blockade induced by Bothrops jararacussu or Crotalus durissus terrificus venoms, probably by precipitating venom proteins (an effect caused by plant tannins). The present study aimed to evaluate the mutagenic activity of P. reticulata by using the Sa
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
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11. Heparin and commercial bothropic antivenom against the paralyzing effect of Bothrops jararacussu snake venom
The crude venom of Bothrops jararacussu (Bjssu) is known to induce muscular paralysis in vitro. Many studies have shown that various substances, including heparin, neutralize the damage caused by snake venom. In the present study, the ability of heparin (Hep) and commercial bothropic antivenom (CBA) to neutralize neuromuscular effects of Bjssu venom, at diff
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 26/02/2010
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12. Bothrops jararacussu venom-induced neuromuscular blockade inhibited by Casearia gossypiosperma Briquet hydroalcoholic extract
The hydroalcoholic extract of Casearia gossypiosperma Briquet (Flacourtiaceae) was standardized for the first time through quality control procedures including pharmacognostic methods, fingerprint chromatograms, defined amounts of marker substances and physicochemical characteristics. The pharmacological activity of C. gossypiosperma (Cg) hydroalcoholic extr
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2010