Neuromuscular Blockers
Mostrando 1-12 de 18 artigos, teses e dissertações.
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1. EVENTS ASSOCIATED WITH THE OCCURRENCE OF INTRACRANIAL HYPERTENSION IN PEDIATRIC PATIENTS WITH SEVERE CRANIOENCEPHALIC TRAUMA AND MONITORING OF INTRACRANIAL PRESSURE
RESUMO Objetivo: Determinar eventos associados à ocorrência de hipertensão intracraniana (HIC) em pacientes pediátricos com traumatismo cranioencefálico grave. Métodos: Trata-se de coorte prospectiva de pacientes de até 18 anos, com traumatismo cranioencefálico, pontuação abaixo de nove na Escala de Coma de Glasgow e monitoração da pressão int
Rev. paul. pediatr.. Publicado em: 13/01/2020
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2. Efeitos dos anestesicos locais na transmissão neuromuscular e no bloqueio produzido pelo rocuronio : estudo experimental / The effects of local anesthetics on the neuromuscular transmission and on the blockade produced by rocuronium : experimental study
Local anesthetics can interact with neuromuscular blockers and modify their pharmacokinetics and pharmacodynamics properties but this mechanism of interaction is very controversial. This experimental study performed in rat phrenic nerve diaphragm preparation and chick biventer cervicis muscle, had the objective to evaluate the effect of different local anest
Publicado em: 2009
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3. Efeitos neuromusculares do atracurio e do rocuronio em ratos pre-tratados com carbamazepina e fenobarbital : estudo in vitro e in vivo / Neuromuscular effects of atracurium and rocuronium in pre treated rats with carbamazepine and phenobarbital : study in vitro e in vivo
Atracurium (ATC) and rocuronium (ROC) are neuromuscular blockers of intermediate action. In this study, the neuromuscular effects had been investigated in vitro and in vivo in treated rats, by gavage (7d), with the anticonvulsantes (AC) carbamazepine (CBZ, 40 mg/kg) and phenobarbital (FB, 20 mg/kg) and sacrificed on the eight day, under anesthesia with ureth
Publicado em: 2007
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4. InfecÃÃo hospitalar em unidade de terapia intensiva pediÃtrica / Healthcare-associated infection in a poaediatric intensive therapy unit
This thesis is presented in the form of three articles, the aim of which was to identify risk factors for healthcare-associated infection (HAI) in a paediatric intensive care unit (PICU) and estimate the effect of these factors on the time elapsed until the first episode of bloodstream infection, confirmed by laboratory exams (BSI-LCBI). The first article is
Publicado em: 2007
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5. Influencia dos anestesicos locais no bloqueio neuromuscular produzido por diferentes bloqueadores neuromusculares : estudo experimental / The influence of local anesthetics on neuromuscular blockade produced by differents neuromusculars blockades : experimental study
Local anesthetics commonly used in clinical practice can interact with neuromuscular blockers and potentiate their effects. Many authors studied this interaction, but the mechanism involved in the potentiation of neuromuscular blockers and the action of local anesthetics in the pre and postjunctional sites were not completely elucidated- In this study, in sp
Publicado em: 2006
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6. AvaliaÃÃo dos nÃveis de pseudocolinesterase em portadores de esquistossomose mansÃnica na forma hepatoesplÃnica
Introduction: The hepatosplenic form of Schistosoma mansoni impairs a numbers of metabolic and liver activities that may interfere with the hepatic anesthetic drugs. The use of neuromuscular blockers in anesthesia are two objectives: 1) to provide relaxations of the muscles for endotracheal intubation; and 2) to preserve suitable conditions for the ventilati
Publicado em: 2004
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7. Emprego do pancuronio e alcuronio em doses de relaxamento muscular para intubação traqueal
The use of competitive neuromuscular blockers in fractional doses is indicated as an alternative technique to accelerate the beginning of blockage and facilitate the quick traqueal intubation. The effects of different priming-doses and the single injection of a total dose of pancuronium and alcuronium on the amplitude of muscular responses, conditions of mus
Publicado em: 1992
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8. Anion blockers inhibit impulse-evoked quantal transmitter release at the crayfish neuromuscular junction
1. The effects of the anion-transport blocking reagents Probenecid, 4,4′diisothiocyanostilbene-2,2′-disulphonate (DIDS), and pyridoxal phosphate on the number of quanta released (m) and the time course of the probability of quantal release, α(t), following an action potential were studied at single synaptic sites on the opener muscle in the crayfish leg
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9. P-type voltage-dependent calcium channel mediates presynaptic calcium influx and transmitter release in mammalian synapses.
We have studied the effect of the purified toxin from the funnel-web spider venom (FTX) and its synthetic analog (sFTX) on transmitter release and presynaptic currents at the mouse neuromuscular junction. FTX specifically blocks the omega-conotoxin- and dihydropyridine-insensitive P-type voltage-dependent Ca2+ channel (VDCC) in cerebellar Purkinje cells. Mam
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10. Effects of a spider toxin on the glutaminergic synapse of lobster muscle.
We studied the effect of neurotoxin (JSTX) separated from spider venom on the lobster neuromuscular junction. JSTX selectively suppressed excitatory post-synaptic potentials (e.p.s.p.s) without affecting the inhibitory post-synaptic potentials (i.p.s.p.s). The effect of JSTX was dose-dependent. The threshold dose for suppressing e.p.s.p.s corresponded to a s
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11. Blockade of neuromuscular transmission by enzymatically active and inactive beta-bungarotoxin.
beta-Bungarotoxins have been shown to be presynaptic blockers of neuromuscular transmission. This paper reports experiments using the most positively charged beta-bungarotoxin that elutes from a CM-Sephadex C-25 column. The toxin is shown to be a single polypeptide with a molecular weight of approximately 11,000 and has phospholipase A2 activity. The applica
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12. Glycerotoxin from Glycera convoluta stimulates neurosecretion by up-regulating N-type Ca2+ channel activity
We report here the purification of glycerotoxin from the venom of Glycera convoluta, a novel 320 kDa protein capable of reversibly stimulating spontaneous and evoked neurotransmitter release at the frog neuromuscular junction. However, glycerotoxin is ineffective at the murine neuromuscular junction, which displays a different subtype of voltage- dependent
Oxford University Press.