Ng Nitroarginine Methyl Ester
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Pharmacological study of the mechanisms involved in the vasodilator effect produced by the acute application of triiodothyronine to rat aortic rings
A relationship between thyroid hormones and the cardiovascular system has been well established in the literature. The present in vitro study aimed to investigate the mechanisms involved in the vasodilator effect produced by the acute application of 10-8–10-4 M triiodothyronine (T3) to isolated rat aortic rings. Thoracic aortic rings from 80 adult male Wis
Braz J Med Biol Res. Publicado em: 25/07/2016
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2. Efeitos da inibição crônica das óxido nítrico sintases na mecânica de tecido periférico, no recrutamento eosinofílico e no remodelamento da matriz extracelular induzida por inflamação crônica pulmonar / Effects of chronic nitric oxide inhibition on lung tissue mechanics, eosinophilic and extracellular matrix responses induced by chronic pulmonary inflammation
INTRODUÇÃO: A importância da resposta mecânica do parênquima pulmonar na fisiopatologia da asma tem sido recentemente reconhecida. O óxido nítrico é um mediador que controla o tônus muscular liso das vias aéreas, porém este efeito no parênquima pulmonar periférico ainda não foi previamente investigado. Nossa hipótese é que a inibição crôni
Publicado em: 2008
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3. Role of nitric oxide in control of prolactin release by the adenohypophysis.
Nitric oxide synthase-containing cells were visualized in the anterior pituitary gland by immunocytochemistry. Consequently, we began an evaluation of the possible role of NO in the control of anterior pituitary function. Prolactin is normally under inhibitory hypothalamic control, and in vitro the gland secretes large quantities of the hormone. When hemipit
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4. Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2.
Proteinase-activated receptor-2 (PAR-2) is a G protein-coupled receptor that is cleaved and activated by trypsin-like enzymes. PAR-2 is highly expressed by small intestinal enterocytes where it is activated by luminal trypsin. The location, mechanism of activation, and biological functions of PAR-2 in the colon, however, are unknown. We localized PAR-2 to th
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5. Hypotension and inflammatory cytokine gene expression triggered by factor Xa–nitric oxide signaling
The signaling pathway initiated by factor Xa on vascular endothelial cells was investigated. Factor Xa stimulated a 5- to 10-fold increased release of nitric oxide (NO) in a dose-dependent reaction (0.1–2.5 μg/ml) unaffected by the thrombin inhibitor hirudin but abolished by active site inhibitors, tick anticoagulant peptide, or Glu-Gly-Arg-chloromethyl k
The National Academy of Sciences.
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6. Nitric oxide released from activated platelets inhibits platelet recruitment.
Vessel injury and thrombus formation are the cause of most ischemic coronary syndromes and, in this setting, activated platelets stimulate platelet recruitment to the growing thrombus. Recently, a constitutive nitric oxide synthase (NOS) has been identified in human platelets. To further define the capacity of platelets to produce nitric oxide (NO), as well