Nitrogen Heterocyclic Bases
Mostrando 1-2 de 2 artigos, teses e dissertações.
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1. Estrutura e reatividade de sulfóxidos de rutênio com bases heterocíclicas nitrogenadas / Structure and reactivity of ruthenium sulfoxides containing nitrogen heterocyclic bases
Ruthenium(II) sulfoxides are compounds of great interest in oxidative catalysis and in chemotherapy. In order to contribute for the understanding of the chemistry and electronic structure of this class of compounds, it has been studied a series of [RuCl2(S-dmso)2Lx] complexes, where x = 1 (polymeric compounds) or 2 (monomers) and L = N-heterocyclic ligands (
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/11/1990
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2. Mechanism of C8 alkylation of guanine residues by activated arylamines: evidence for initial adduct formation at the N7 position.
Aromatic amines are bioactivated to electrophilic compounds that react with DNA, predominantly at the C8 position of guanine bases. This site is weakly nucleophilic and it has been proposed that the C8 adduct is the final product after initial N7-adduct formation. To consider this possibility, we reacted several C8-substituted guanine derivatives with N-acet