Nitrosil Of Ruthenium
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Identification of mechanisms involved in the relaxation of rabbit cavernous smooth muscle by a new nitric oxide donor ruthenium compound
PURPOSE: The aim of this study was to evaluate the relaxation in vitro of cavernous smooth muscle induced by a new NO donor of the complex nitrosil-ruthenium, named trans-[Ru(NH3)4(caffeine)(NO)]C13 (Rut-Caf) and sodium nitroprusside (SNP). MATERIALS AND METHODS: The tissues, immersed in isolated bath systems, were pre-contracted with phenilephrine (PE) (1 �
Int. braz j urol.. Publicado em: 2012-10
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2. Comportamento em solução de P(OH)(OEt)2 e P(OH)3 coordenados a tetraaminas de Ru(II) / Behavior in solution of P(OH)(OEt)2 and P(OH)3 coordinated to ruthenium(II) tetraammines
The stability of the ligand diethyl phosphite was analyzed by 1H NMR in solution at pH 1.0 and 3.0 and 25°C in the presence and in the absence of the ion [RuII(H2O)(NH3)5]2+. The hydrolysis of the free diethyl phosphite in solution at pH 3.0 was not observed, while in the presence of the ion [RuII(H2O)(NH3)5]2+, at this same pH, the reaction took place w
Publicado em: 2010
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3. Efeitos do nitrosil rutÃnio na lesÃo cerebral induzida por isquemia e reperfusÃo em ratos wistar / Effects of nitrosyl ruthenium in injury brain induced by ischemia and reperfusion of rats
IntroduÃÃo e objetivo: Doadores de NO podem diminuir a lesÃo neuronal durante a isquemia e reperfusÃo cerebral (I/R) por aumento do fluxo sanguÃneo cerebral. O objetivo deste estudo à avaliar se um novo complexo de nitrosilo complexo de rutÃnio (Rut-bpy) capaz liberar NO direto na musculatura lisa vascular apresenta algum efeito durante I/R. MÃtodo:
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/11/2009
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4. Dissociation of HNO and NO: leishmanicidal activity of nitrosil of ruthenium / Liberação de HNO e NO por nitrosilos de rutênio e sua atividade antileishmania
Ruthenium complexes type trans-[RuNO(NH3)4L](X)3 (X = BF4- or PF6- and L = imN, 4-pic, isn, py, pz, L- hist, nic, imC, P(OEt)3, SO32-), and [RuNO(Hedta)] were tested as antiproliferative agents against the Leishmania major parasite. The complexes where L = imN, pz, 4-pic, py, isn, and P(OEt)3 exhibited IC50pro ranging from 36 for trans-[RuNO(NH3)4imN](BF4)3
Publicado em: 2009
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5. Syntheses, Characterization and Chemical Reactivity of Chloro and Nitrosyl Complexes of trans-Tetrakispyridines of Ruthenium / Síntese, caracterização e reatividade química de complexos de cloro e nitrosil de trans-Tetrakispiridina de rutênio
The complexes trans-[RuCl2(L)4] (L = py, isn, 4-acpy e 3-acpy), trans-[RuCl(NO)(L)4](PF6)2 (L = py, isn e 4-acpy), trans-[Ru(OH)(NO)(py)4](PF6)2, trans-[RuCl(NO)(py)4]Cl23H2O, trans-[Ru(OH)(NO)(py)4]Cl2, cis-[RuCl2(DMSO)4], trans-[Ru(NO2)2(py)4], trans-[RuCl(NO2)(py)4], trans-[RuCl(acn)(py)4](PF6) and the reduced complex trans-[RuCl(NO)(py)4]I were synthesiz
Publicado em: 2009
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6. Síntese, caracterização e estudo de reatividade dos complexos cis-[Ru(bpy)2(TU)(H2O)](PF6)2 E cis-[Ru(bpy)2(TU)(NO)](PF6)3 / Synthesis, characterization and reactivity study of the complexes cis-[Ru(bpy)2(TU)(H2O)](PF6)2 E cis-[Ru(bpy)2(TU)(NO)](PF6)3
Neste trabalho foi realizada a síntese e a caracterização dos complexos cis-[Ru(bpy)2(TU)(H2O)](PF6)2 e cis-[Ru(bpy)2(TU)(NO)](PF6)3, onde TU=Tiouréia e bpy= 2,2-bipiridina, bem como os estudos preliminares relacionados a reatividade do nitrosilo-complexo frente a luz branca e na presença do redutor biológico cisteína. O aquo-complexo possui o ligante
Publicado em: 2009
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7. IdentificaÃÃo dos mecanismos envolvidos no relaxamento da musculatura lisa cavernosa e da aorta de coelho, induzido por doadores de Ãxido nÃtrico do complexo nitrosil-rutÃnio / Identification of the involved mechanisms in the relaxation of the cavernous smooth musculatura and aorta of rabbit, induced for nitric oxide givers of the nitrosil-rutÃnio complex
Endothelial dysfunction makes 56% of patients with erectile dysfunction decline treatment with PDE-5 inhibitors. New forms of treatment are necessary for this group of patients. The present study evaluates the relaxation in vitro induced in rabbit corpus cavernosum smooth muscle and aortic rings by sodium nitroprusside (SNP) and by two new NO-donor substance
Publicado em: 2008
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8. Ruthenium complexes with nitrosil group as donnors agents of nitric oxide. Chemical and Physical aspects of its applications as therapeutical agents" / Complexos de rutênio com nitrosil como agentes doadores de óxido nítrico. Aspectos químicos e físico-químicos de suas aplicações como agentes terapêuticos"
Nitric oxide activity in chemistry and biology is not yet fully discovered. There are more than 5,000 papers alone on this subject each year. A lot more work needs to be done in this area. For people in biology who want to study how nitric oxide works in different systems, they need some kind of model compound to release nitric oxide to help them do their ph
Publicado em: 2004