Nonprotein Sulfhydryl
Mostrando 1-12 de 15 artigos, teses e dissertações.
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1. Acute effects of resistance exercise and intermittent intense aerobic exercise on blood cell count and oxidative stress in trained middle-aged women
The aim of this study was to compare the effect of an intermittent intense aerobic exercise session and a resistance exercise session on blood cell counts and oxidative stress parameters in middle-aged women. Thirty-four women were selected and divided into three groups: RE group (performing 60 min of resistance exercises, N = 12), spinning group (performing
Braz J Med Biol Res. Publicado em: 2012-12
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2. Antinociceptive and anti-ulcerogenic activities of the ethanolic extract of Annona muricata leaf
Ethanolic extract of Annona muricata L., Annonaceae, leaf (AML) was used to investigate its antinociceptive and anti-ulcerogenic activities and the involvement of the mechanism of ethanolic leaves extract of AML in various animal models. Antinociceptive activity of AML extract was done using acetic acid-induced abdominal writhing in mice, formalin test in ra
Revista Brasileira de Farmacognosia. Publicado em: 06/01/2012
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3. The gastroprotective effect of amifostine (ETHYOLÂ) on ethanol-induced gastric injury in rats: the role of non-protein sulfhydryl groups and afferent sensory nerves / Efeito gastroprotetor da amifostina (ETHYOLÂ) na lesÃo gÃstrica induzida por etanol em ratos: papel dos grupos sulfidrÃlicos nÃo-protÃicos e neurÃnios sensoriais aferentes
INTRODUÃÃO: A amifostina (WR-2721) tem sido largamente estudada como agente citoprotetor em diferentes ÃrgÃos e contra os mais diversos agressores do organismo humano. Recentemente, um efeito gastroprotetor deste fÃrmaco foi observado em modelo de lesÃo gÃstrica induzida por indometacina (MOTA et al., 2007). OBJETIVOS: Este trabalho investigou o efeit
Publicado em: 2008
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4. Pre-clinical study of gastroprotective effect of mangiferin, a glucosylxanthone from Mangifera indica L., in experimental models of acute gastric mucosal injury / Estudos prÃ-clÃnicos do efeito gastroprotetor da mangiferina, uma glicosilxantona isolada de Mangifera indica L., em modelos experimentais de lesÃo gÃstrica aguda
Mangiferin, a glucosylxanthone from the fruiting tree Mangifera indica Linn. (Anacardiaceae), was evaluated for the first time in acute models of gastric injury. Mangiferin (3, 10 and 30 mg/kg, p.o.) significantly attenuated (p<0,001) the gastric damage induced by ethanol (30, 35 and 63% of reduction), acidified ethanol (27, 44 and 78% of inhibition), indome
Publicado em: 2008
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5. Antioxidant responses of Laeonereis acuta (Polychaeta) after exposure to hydrogen peroxide
The effects of H2O2 were evaluated in the estuarine worm Laeonereis acuta (Polychaeta, Nereididae) collected at the Patos Lagoon estuary (Southern Brazil) and maintained in the laboratory under controlled salinity (10 psu diluted seawater) and temperature (20°C). The worms were exposed to H2O2 (10 and 50 µM) for 4, 7, and 10 days and the following variable
Brazilian Journal of Medical and Biological Research. Publicado em: 20/12/2007
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6. Efeitos do chumbo sobre a atividade da tioredoxina redutase citosólica (TrxR1) e parâmetros de estresse oxidativo em rins de ratos. / Effects of lead acetate exposure on renal cytosolic thioredoxin reductase (TrxR1) activity and on indicators of lead exposure.
Lead is a heavy metal that accumulates primarily in kidney, where exerts its nephrotoxic effects. Several studies suggest that the oxidative stress is an important molecular mechanism for the toxic effects of lead in kidney and in other organs. Cytosolic thioredoxin reductase (TrxR1) is a selenoflavoprotein involved in many processes modulating intracellular
Publicado em: 2007
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7. Oxidative stress in the erythrocytes of cattle intoxicated with Senecio sp. / Estresse oxidativo em eritrócitos de bovinos intoxicados por Senecio sp.
Intoxicação causada por Senecio sp é caracterizada por danos irreversíveis às células hepáticas e pode estar associada com estresse oxidativo. O objetivo deste estudo foi avaliar os efeitos da intoxicação por Senecio sp sobre a peroxidação lipídica, defesa antioxidante e resistência osmótica dos eritrócitos em bovinos. Amostras sanguíneas de
Publicado em: 2006
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8. LIVER NONPROTEIN SULFHYDRYL OF ENDOTOXIN-TREATED MICE
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9. Prevention of doxorubicin cardiac toxicity in the mouse by N-acetylcysteine.
This study was undertaken to investigate the effect of exogenous sulfhydryl compound administration on the toxicity of doxorubicin in mice. Pretreatment of CDF1 mice with a pharmacologic dose (2,000 mg/kg) of n-acetyl-l-cysteine 1 h before doxorubicin (20 mg/kg, i.p.) decreased lethality from 100% (n = 44) to 37.7% (n = 53), P less than 0.001. Variation in t
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10. Involvement of Oxidative Processes in the Signaling Mechanisms Leading to the Activation of Glyceollin Synthesis in Soybean (Glycine max).
The efficiency of hydroperoxides (tert-butyl hydroperoxide, hydrogen peroxide) and sulfhydryl reagents (iodoacetamide, p-chloromercuribenzene sulfonic acid) as glyceollin elicitors was examined in relation to sulfhydryl oxidation, or alteration, and to lipid peroxidation, in 3-d-old soybean hypocotyl/radicle, Glycine max. These oxidative events were investig
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11. Ozone interaction with rodent lung. III. Oxidation of reduced glutathione and formation of mixed disulfides between protein and nonprotein sulfhydryls.
Nonprotein sulfhydryls (NPSH), a major source of cellular reducing substances, were examined in lung tissue after short-term exposure of rats to O3. While the NPSH level was unaffected by low-level exposures (e.g., 0.8 ppm for up to 24 h or 1.5 ppm for up to 8 h), it was significantly lowered by higher exposure regimens (e.g., 25 per cent after 2 ppm for 8 h
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12. Base substitution mutations induced in the cI gene of lambda phage by neocarzinostatin chromophore: correlation with depyrimidination hotspots at the sequence AGC.
Treatment of intact lambda phage with the nonprotein chromophore of neocarzinostatin resulted in efficient phage inactivation and generation of clear-plaque mutants. Both effects required a preincubation at low pH to allow diffusion of chromophore into the phage head. Chromophore activation was then effected by addition of a sulfhydryl cofactor, followed by