Nucleoprotein N
Mostrando 1-12 de 193 artigos, teses e dissertações.
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1. Evaluation of short-interfering RNAs treatment in experimental rabies due to wild-type virus
ABSTRACTWe have evaluated the efficacy of short-interfering RNAs targeting the nucleoprotein gene and also the brain immune response in treated and non-treated infected mice. Mice were inoculated with wild-type virus, classified as dog (hv2) or vampire bat (hv3) variants and both groups were treated or leaved as controls. No difference was observed in the le
Braz J Infect Dis. Publicado em: 2015-10
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2. Fluorescent antibody test, quantitative polymerase chain reaction pattern and clinical aspects of rabies virus strains isolated from main reservoirs in Brazil
ABSTRACTRabies virus (RABV) isolated from different mammals seems to have unique characteristics that influence the outcome of infection. RABV circulates in nature and is maintained by reservoirs that are responsible for the persistence of the disease for almost 4000 years. Considering the different pattern of pathogenicity of RABV strains in naturally and e
Braz J Infect Dis. Publicado em: 2015-10
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3. In vitro and in vivo inhibition of rabies virus replication by RNA interference
Rabies is a zoonotic disease that affects all mammals and leads to more than 55,000 human deaths every year, caused by rabies virus (RABV) (Mononegavirales: Rhabdoviridae: Lyssavirus). Currently, human rabies treatment is based on the Milwaukee Protocol which consists on the induction of coma and massive antiviral therapy. The aim of this study was to assess
Braz. J. Microbiol.. Publicado em: 15/11/2013
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4. Um enfoque multigênico para a genealogia comparada de Betacoronavirus em bovinos e equinos / A multigene approach for a compared genealogy of Betacoronavirus from cattle and horses
Gastroenteritis is one of the leading causes of morbidity and mortality amongst young and newborn animals, often caused by multiple intestinal infections, being rotavirus and Bovine coronavirus (BCoV) the main viral causes in cattle. BCoV has a worldwide distribution and caused diarrhea in calves, winter dysentery in adult cattle and respiratory disease, whi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/01/2011
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5. Montagem de um pseudo-hantavírus quimera, contendo a nucleoproteína do vírus Araraquara e as glicoproteínas do vírus Andes, em sistema baculovírus / Assembly of a chimeric hantavirus-like particle, containing the Araraquara nucleoprotein and the Andes glycoproteins, expressed in baculovirus system
Hantaviruses, members of the Bunyaviridae family, are the infectious agents responsible for Hemorrhagic Fever with Renal Syndrome and the Hantavirus Cardiopulmonary Syndrome. The viral genome is composed by three segments of single-stranded negative-sense RNA, designated as S, M and L, which encode, respectively, the nucleoprotein, the G1 and G2 glycoprotein
Publicado em: 2010
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6. Filogenia de vírus da raiva isolados de morcegos frugívoros do gênero Artibeus e relacionados a morcegos hematófagos com base nos genes codificadores da nucleoproteína N e glicoproteína G / Phylogeny of rabies virus strains from Artibeus spp. and Desmodus rotundus bats based on the nucleoprotein and glycoprotein genes
Morcegos vêm recebendo crescente importância em Saúde Pública, pois são os principais reservatórios para a raiva em diversas partes do mundo. Estudos filogenéticos baseados no gene N demonstraram que os vírus da raiva (RABV) encontrados em morcegos frugívoros Artibeus spp. são próximos àqueles associados ao morcego hematófago Desmodus rotundus,
Publicado em: 2009
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7. Rabies virus in insectivorous bats: implications in molecular epidemiology of the diversity of genes encoding nucleoprotein and glycoprotein / Vírus da raiva em morcegos insetívoros: implicações em epidemiologia molecular da diversidade dos genes codificadores da nucleoproteína e glicoproteína
As a result of the control of canine rabies in São Paulo State in the last 20 years, rabies in wild animals, mainly in bats, has assumed an increasing importance as the last are currently the most important rabies reservoirs in this State. Despite the fact that bats have maintained epidemiological cycles of rabies for centuries, only in the 50s rabies in in
Publicado em: 2009
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8. Diversidade genética de amostras brasileiras do vírus da bronquite infecciosa determinada pelo seqüenciamento de nucleotídeos dos genes N e S1. / Genetic diversity of Brazilian isolates of infections bronchitis virus by the sequencing of N and S1 genes.
Foram submetidos à análise molecular, 15 isolados do vírus da bronquite infecciosa (VBI) obtidos durante o período de 1988 a 2000, de surtos à campo da Bronquite Infecciosa (BI), em aves de corte ou de postura das regiões Sul e Sudeste do Brasil. Os resultados obtidos da análise filogenética das sequências parciais dos genes da glicoproteína de esp
Publicado em: 2008
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9. Avaliação da urina e de leucócitos como amostras biológicas para a detecção ante mortem do vírus da cinomose canina por RT-PCR em cães naturalmente infectados
Urine and leucocytes were comparatively evaluated as clinical samples for ante mortem detection of the canine distemper virus (CDV) by a reverse transcription-polymerase chain reaction (RT-PCR) assay. One hundred and eighty eight dogs with clinical symptoms of distemper, were distributed in three groups. The group A was constituted of 93 dogs with systemic s
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Publicado em: 2007-02
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10. Purification of the recombinant rabies virus G glycoprotein (GPV) produced by Drosophila melanogaster S2 cells using immobilized metal ion affinity chromatography / Purificação da glicoproteina G (GPV) recombinante do virus da raiva produzida por celulas de Drosophila melanogaster S2 atraves de cromatografia de afinidade por ions metalicos imobilizados
Rabies or hydrophobia is a viral infection that affects the central nervous system, occuring in animals and humans. The main proteins found in rabies virus that activates the immunological system are the N nucleoprotein (NPV) and the G glycoprotein, a transmembrane protein that forms the spikes of the virus and induces virus-neutralizing antibodies that prot
Publicado em: 2007
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11. Purificação da glicoproteina G (GPV) recombinante do virus da raiva produzida por celulas de Drosophila melanogaster S2 atraves de cromatografia de afinidade por ions metalicos imobilizados / Purification of the recombinant rabies virus G glycoprotein (GPV) produced by Drosophila melanogaster S2 cells using immobilized metal ion affinity chromatography
Rabies or hydrophobia is a viral infection that affects the central nervous system, occuring in animals and humans. The main proteins found in rabies virus that activates the immunological system are the N nucleoprotein (NPV) and the G glycoprotein, a transmembrane protein that forms the spikes of the virus and induces virus-neutralizing antibodies that prot
Publicado em: 2007
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12. Diagnosis of human rabies cases by polymerase chain reaction of neck-skin samples
Rapid diagnosis of rabies in suspected human cases influences post-exposure prophylaxis for potential contacts of the patient and ensures appropriate patient management. Apart from the central nervous system (CNS), rabies virus (RABV) is usually present in small sensory nerves adjacent to hair follicles of infected humans. We used an RT-PCR, with primers tar
Brazilian Journal of Infectious Diseases. Publicado em: 2006-10