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Mostrando 1-12 de 4049 artigos, teses e dissertações.
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1. Revisiting global cognitive and functional state 13 years after a clinical trial of lithium for mild cognitive impairment
Objectives: To re-evaluate a sample of older adults enrolled in a randomized controlled trial of lithium for amnestic mild cognitive impairment (MCI) after 11 to 15 years, re-assessing their current (or last available) global cognitive and functional state. Methods: We recalled all former participants of the Lithium-MCI trial conducted by our group between
Brazilian Journal of Psychiatry. Publicado em: 2023
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2. Applicability of an immersive virtual reality system to assess egocentric orientation of older adults
Resumo Antecedentes A orientação espacial é um domínio cognitivo frequentemente comprometido em pacientes com doença de Alzheimer (DA) e pode ser uma das suas primeiras manifestações clínicas. Alguns estudos demonstraram que a integração alocêntrica com informações espaciais egocêntricas parece prejudicada nessa patologia. Não há um consenso
Arquivos de Neuro-Psiquiatria. Publicado em: 2023
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3. An inconvenient status in anti-osteoporotic treatment process: corticosteroid use
SUMMARY OBJECTIVE: There are limited studies investigating the comparison of the efficacy of anti-osteoporotic drugs in different conditions resulting in osteoporosis in older adults. This study aimed to compare the effectiveness of anti-osteoporotic agents in older adults with or without glucocorticoid-induced osteoporosis. METHODS: This retrospective stu
Revista da Associação Médica Brasileira. Publicado em: 2022
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4. Hospitalization due to mental and behavioral disorders caused by use of alcohol and psychoactive substances among older adults and elderly people in Brazil: a cross-sectional study
ABSTRACT BACKGROUND: It has been estimated that 17% of individuals aged 50 years or older suffer from addiction to legal or illegal drugs. Use of alcohol and psychoactive substances has been correlated with several diseases, e.g. psychiatric conditions and cardiovascular and sexual dysfunctions. Objective: To discuss the Brazilian profile of mental and beh
Sao Paulo Medical Journal. Publicado em: 2022
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5. Relationships between self-reported dyspnea, health conditions and frailty among Brazilian community-dwelling older adults: a cross-sectional study
ABSTRACT CONTEXT: Dyspnea is a symptom present in several chronic diseases commonly seen among older adults. Since individuals with dyspnea tend to stay at rest, with consequently reduced levels of physical activity, they are likely to be at greater risk of developing frailty, especially at older ages. DESIGN AND SETTING: Cross-sectional study at community
Sao Paulo Medical Journal. Publicado em: 2022
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6. Poor physical fitness is associated with impaired memory, executive function, and depression in institutionalized older adults: a cross-sectional study
Objective: To analyze the association between physical fitness, cognitive function, and depressive symptoms among older adults in long-term care facilities (LTCFs). Methods: Seventy-six institutionalized male and female elderly individuals (65 years and older) living in LTCFs participated of this study. Physical fitness (aerobic capacity and strength), cogn
Brazilian Journal of Psychiatry. Publicado em: 2022
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7. Association between falls and cognitive performance among community-dwelling older people: a cross-sectional study
ABSTRACT BACKGROUND: Falls among older people have a negative impact on health and therefore constitute a public health problem. Cognitive decline can also accompany the aging process, and both conditions lead to significant increases in morbidity and mortality in this population. Objective: To analyze the cognitive performance of older people, classified
Sao Paulo Medical Journal. Publicado em: 2022
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8. Sociodemographic determinants of multimorbidity in Brazilian adults and older adults: a cross-sectional study
ABSTRACT BACKGROUND: Multimorbidity due to non-communicable chronic diseases (NCDs) constitutes a significant challenge for healthcare systems. To attenuate its impacts, it is essential to identify the sociodemographic determinants of this condition, which can discriminate against population segments that are more exposed. OBJECTIVE: To identify associatio
Sao Paulo Medical Journal. Publicado em: 2022
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9. Use of Diuretics is Associated with Higher Risk of Sarcopenia in Older Adults with Hypertension
Abstract Background: Sarcopenia is a disease that involves skeletal muscle mass loss and is highly prevalent in the older adult population. Moreover, the incidence of sarcopenia is increased in patients with hypertension. Objectives: The study aimed to evaluate the association between the classes of the drugs used for arterial hypertension treatment and th
International Journal of Cardiovascular Sciences. Publicado em: 2022
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10. Suicide after and during the COVID-19 pandemic in Mexico City
Objectives: Prior research has indicated that no increase in suicides occurred immediately following the declaration of the COVID-19 emergency in Mexico City. Here we examine longer-term overall suicide trends and trends according to basic demographic groups. Methods: We used interrupted time-series analysis to model trends in monthly suicides before COVID-
Brazilian Journal of Psychiatry. Publicado em: 2022
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11. Evaluation of 10-minute post-injection 11C-PiB PET and its correlation with 18F-FDG PET in older adults who are cognitively healthy, mildly impaired, or with probable Alzheimer’s disease
Objective: Positron emission tomography (PET) allows in vivo evaluation of molecular targets in neurodegenerative diseases, such as Alzheimer’s disease. Mild cognitive impairment is an intermediate stage between normal cognition and Alzheimer-type dementia. In vivo fibrillar amyloid-beta can be detected in PET using [11C]-labeled Pittsburgh compound B (11C
Brazilian Journal of Psychiatry. Publicado em: 2022
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12. Decision tree-based classification as a support to diagnosis in the Alzheimer’s disease continuum using cerebrospinal fluid biomarkers: insights from automated analysis
Objective: Cerebrospinal fluid (CSF) biomarkers add accuracy to the diagnostic workup of cognitive impairment by illustrating Alzheimer’s disease (AD) pathology. However, there are no universally accepted cutoff values for the interpretation of AD biomarkers. The aim of this study is to determine the viability of a decision-tree method to analyse CSF bioma
Brazilian Journal of Psychiatry. Publicado em: 2022