Oral Clefts
Mostrando 1-12 de 31 artigos, teses e dissertações.
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1. Qual a idade para realização da cirurgia de correção das deformidades maxilares em paciente fissurado? Quais os objetivos do tratamento?
A correção cirúrgica das deformidades maxilares é mais bem realizada quando o esqueleto está maduro e os dentes foram ortodonticamente alinhados. O crescimento craniofacial está geralmente completo entre as idades de 14 e 16 anos, nas mulheres, e entre 16 e 18 anos, nos homens. Todavia, o crescimento esquelético é variável, e uma avaliação do f
Núcleo de Telessaúde Sergipe. Publicado em: 12/06/2023
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2. Identification of genomic imbalances in oral clefts
Abstract Objective This article presents a clinical and cytogenomic approach that focuses on the diagnosis of syndromic oral clefts (OCs). Methods The inclusion criteria were individuals with OC presenting four or more minor signs and no major defects (non-syndromic oral clefts [NSOCs]) as well as individuals with OC presenting at least another major defec
J. Pediatr. (Rio J.). Publicado em: 2021-06
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3. Merging Pediatric Index of Mortality (a physiologic instability measure), lactate, and Systemic Inflammation Mortality Risk to better predict outcome in pediatric sepsis
Abstract Objective This article presents a clinical and cytogenomic approach that focuses on the diagnosis of syndromic oral clefts (OCs). Methods The inclusion criteria were individuals with OC presenting four or more minor signs and no major defects (non-syndromic oral clefts [NSOCs]) as well as individuals with OC presenting at least another major defec
J. Pediatr. (Rio J.). Publicado em: 2021-06
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4. Assessing the association between hypoxia during craniofacial development and oral clefts
Abstract Objectives To evaluate the association between hypoxia during embryo development and oral clefts in an animal model, and to evaluate the association between polymorphisms in the HIF-1A gene with oral clefts in human families. Material and Methods The study with the animal model used zebrafish embryos at 8 hours post-fertilization submitted to 30%
J. Appl. Oral Sci.. Publicado em: 21/05/2018
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5. Cardiovascular abnormalities in patients with oral cleft: a clinical-electrocardiographic-echocardiographic study
OBJECTIVES: The present study aims to describe the clinical, electrocardiographic, and echocardiographic cardiological findings in a group of patients with oral clefts. METHODS: This is a prospective cross-sectional study on 70 children (age range from 13 days to 19 years) with oral clefts who attended the multidisciplinary program of a university hospital
Clinics. Publicado em: 19/04/2018
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6. Risk factors and comorbidities in Brazilian patients with orofacial clefts
Abstract: Considering that environmental risk factors substantially contribute to the etiology of orofacial clefts and that knowledge about the characteristics and comorbidities associated with oral clefts is fundamental to promoting better quality of life, this study aimed to describe the risk factors, main characteristics, and comorbidities of a group of p
Braz. oral res.. Publicado em: 05/04/2018
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7. Oral health-related quality of life of children with oral clefts and their families
Abstract Oral health problems can influence people's Quality of Life (QoL) because of pain, discomfort, limitations, and other esthetics problems, affecting their social life, feeding, daily activities, and the individual's well-being. Objective: To compare oral health-related quality of life (OHRQoL) of children with and without oral clefts and their famil
J. Appl. Oral Sci.. Publicado em: 01/02/2018
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8. Orofacial clefts in Brazil and surgical rehabilitation under the Brazilian National Health System
Abstract The objective of this study was to investigate the prevalence of live births with orofacial clefts in Brazil from 2009 to 2013, according to Brazil’s federative units and regions, and correlate it with the number of corrective surgery procedures for cleft lip and palate performed through the Brazilian National Health System in the same period. The
Braz. oral res.. Publicado em: 30/03/2017
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9. The functional EGF+61 polymorphism and nonsyndromic oral clefts susceptibility in a Brazilian population
AbstractNonsyndromic oral clefts are considered a problem of public health in Brazil, presenting a multifactorial etiology that involves genetic and environmental components, such as maternal alcohol consumption. Several candidate genes have been investigated to identify some association with nonsyndromic clefts risk. The epidermal growth factor (EGF) gene i
J. Appl. Oral Sci.. Publicado em: 2015-08
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10. Risk factors and the prevention of oral clefts
This article presents general aspects of risk factors and particularities of the management of individuals with oral clefts (OCs). A practical manual of prevention and management of this congenital defect was prepared based on a review of the literature and using data from Brazilian multicenter studies. Since OCs require efforts from all levels of healthcare
Braz. oral res.. Publicado em: 12/01/2014
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11. Molecular analysis of holoprosencephaly in South America
Holoprosencephaly (HPE) is a spectrum of brain and facial malformations primarily reflecting genetic factors, such as chromosomal abnormalities and gene mutations. Here, we present a clinical and molecular analysis of 195 probands with HPE or microforms; approximately 72% of the patients were derived from the Latin American Collaborative Study of Congenital
Genet. Mol. Biol.. Publicado em: 2014
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12. MSX1 gene and nonsyndromic oral clefts in a Southern Brazilian population
Nonsyndromic oral clefts (NSOC) are the most common craniofacial birth defects in humans. The etiology of NSOC is complex, involving both genetic and environmental factors. Several genes that play a role in cellular proliferation, differentiation, and apoptosis have been associated with clefting. For example, variations in the homeobox gene family member MSX
Braz J Med Biol Res. Publicado em: 16/07/2013