Osteoblastic Differentiation
Mostrando 1-12 de 68 artigos, teses e dissertações.
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1. Combined effects of melatonin and FGF-2 on mouse preosteoblast behavior within interconnected porous hydroxyapatite ceramics - in vitro analysis
ABSTRACT Objective Biocompatible materials such as interconnected porous hydroxyapatite ceramics (IP-CHA) loaded with osteogenic cells and bioactive agents are part of an evolving concept for overcoming craniofacial defects by use of artificial bone tissue regeneration. Amongst the bioactive agents, melatonin (MEL) and basic fibroblast growth factor (FGF-2
J. Appl. Oral Sci.. Publicado em: 2016-04
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2. The effects of 6-gingerol on proliferation, differentiation, and maturation of osteoblast-like MG-63 cells
We investigated whether 6-gingerol affects the maturation and proliferation of osteoblast-like MG63 cells in vitro. Osteoblast-like MG63 cells were treated with 6-gingerol under control conditions, and experimental inflammation was induced by tumor necrosis factor-α (TNF-α). Expression of different osteogenic markers and cytokines was analyzed by real-time
Braz J Med Biol Res. Publicado em: 28/04/2015
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3. Expression of osteoblastic phenotype in periodontal ligament fibroblasts cultured in three-dimensional collagen gel
Objective : To investigate the influence of a three-dimensional cell culture model on the expression of osteoblastic phenotype in human periodontal ligament fibroblast (hPDLF) cultures. Material and Methods : hPDLF were seeded on bi-dimensional (2D) and three-dimensional (3D) collagen type I (experimental groups) and and on a plastic coverslip (control) for
J. Appl. Oral Sci.. Publicado em: 2015-04
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4. Adenovirus-mediated siRNA targeting TNF-α and overexpression of bone morphogenetic protein-2 promotes early osteoblast differentiation on a cell model of Ti particle-induced inflammatory response in vitro
Wear particles are phagocytosed by macrophages and other inflammatory cells, resulting in cellular activation and release of proinflammatory factors, which cause periprosthetic osteolysis and subsequent aseptic loosening, the most common causes of total joint arthroplasty failure. During this pathological process, tumor necrosis factor-alpha (TNF-α) plays a
Braz J Med Biol Res. Publicado em: 2013-10
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5. Overexpression of hsa-miR-125b during osteoblastic differentiation does not influence levels of Runx2, osteopontin, and ALPL gene expression
Multipotent mesenchymal stromal cells (MSCs) were first isolated from bone marrow and then from various adult tissues including placenta, cord blood, deciduous teeth, and amniotic fluid. MSCs are defined or characterized by their ability to adhere to plastic, to express specific surface antigens, and to differentiate into osteogenic, chondrogenic, adipogenic
Braz J Med Biol Res. Publicado em: 2013-08
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6. In vitro osteoblastic differentiation on bioactive glass and glassceramic surfaces / Análise da diferenciação osteoblástica in vitro sobre superfícies de materiais vítreos e vitrocerâmicos bioativos
Materiais vítreos e vitrocerâmicos bioativos podem ser usados particulados ou como scaffolds em diferentes tratamentos de defeitos ósseos. Tratamentos térmicos que possibilitam o desenvolvimento de scaffolds a partir de composições de vidros bioativos introduzem fases cristalinas em sua estrutura amorfa com potencial impacto na bioatividade e biocompat
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/08/2012
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7. Avaliação histométrica do reparo de defeito ósseo em calvária de rato após implante de rhMMP-2 ligada à monoleína / Histometric evaluation of bone healing after implantation with rhMMP-2 linked to monolein into rat calvarial defects
Matrix metalloproteinases (MMPs) are zinc-dependent proteolytic enzymes that degrade extracellular matrix components, facilitating cell migration and tissue remodeling. MMPs secreted by osteclasts are important in the physiological bone resorption as in pathological bone degradation. However, the essentially bone absorbing hole of MMPs, particularly of the M
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/08/2012
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8. Effects of low-level laser therapy on human osteoblastic cells grown on titanium
The aim of this study was to investigate the effects of low-level laser therapy (LLLT) by using gallium aluminum arsenide (GaAlAs) diode laser on human osteoblastic cells grown on titanium (Ti). Osteoblastic cells were obtained by enzymatic digestion of human alveolar bone and cultured on Ti discs for up to 17 days. Cells were exposed to LLLT at 3 J/cm2 (wav
Brazilian Dental Journal. Publicado em: 2010
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9. Análise proteômica das diversas fases de diferenciação osteoblástica de células-tronco mesenquimais de medula óssea / Proteomics analysis of the various stages of osteoblastic differentiation of mesenchymal stem cells from bone marrow
O crescimento, desenvolvimento e manutenção do tecido ósseo são processos altamente regulados. Diversas proteínas como hormônios, fatores de crescimento e citocinas estão envolvidas nestes processos e exercem atividade direta sobre células osteoblástica e osteoclástica, atuando em sua diferenciação e ativação metabólica. O processo de regenera
Publicado em: 2010
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10. Funcionalização de microtopografia de titânio com peptídeo sintético de colágeno I (P-15): efeitos sobre o desenvolvimento do fenótipo osteogênico in vitro / Development of the osteogenic phenotype in vitro on titanium surface microtopography functionalized with a type I collagen-derived synthetic peptide (P-15).
Os eventos celulares e extracelulares que ocorrem durante o processo de osseointegração do titânio (Ti) são influenciados pelas propriedades físicas e químicas de sua superfície. Modificações bioquímicas de topografias complexas de Ti permitem o desenvolvimento de novas superfícies de implantes funcionalizadas com moléculas bioativas, visando a p
Publicado em: 2010
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11. Flavins promote changes in the extracellular matrix, signal transduction, antioxidant enzymes and metalloproteinases during osteoblast differentiation / Flavinas promovem mudanças na matriz extracelular, vias de transdução de sinal, enzimas antioxidantes e metaloproteinases durante a diferenciação de osteoblastos
Riboflavin (Rb-Vitamin B2) is the precursor of essential flavocoenzymes, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). These coenzymes participate in numerous enzymatic processes dependent on electron transfer reactions that occur in energyproducing, biosynthetic, and detoxifying and electron-scavenging pathways. Increase dietary ribofla
Publicado em: 2009
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12. Expression of gap junction proteins, the connexins, in normal and neoplastic osseous tissues from dogs / Estudo da expressão das proteínas de junções intercelulares do tipo Gap, as conexinas, em tecido ósseo normal e neoplásico de cães
Increasing evidence indicates that junctional communiction by gap juctions has a critical role in a bone physiology. The main connexin (Cx) express involved in development, differentiation and regulation of tissue growth, is the called Cx43. However, other, two connexis are expressed: Cx45 and Cx46. Cx46 is retained as monomers in a trans-golgi compartment o
Publicado em: 2008