Oxidative Lesions
Mostrando 1-12 de 180 artigos, teses e dissertações.
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1. The Investigation of the Relationship Between HSP-27 Release and Oxidative DNA Damage in Broiler Chickens with Tibial Dyschondroplasia by Using Histopathological and Immunohistochemical Methods
ABSTRACT Tibial dyschondroplasia (TD) is a skeletal disorder that occurs in the proximal metaphyses of tibiotarsus and sometimes tarsometatarsus, resulting in the development of avascularized and non-mineralized abnormal cartilage and causing significant economic loss. In this study, we aimed to show the histopathological changes and the relationship between
Braz. J. Poult. Sci.. Publicado em: 05/12/2019
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2. Antioxidant action of alpha lipoic acid on the testis and epididymis of diabetic rats: morphological, sperm and immunohistochemical evaluation
ABSTRACT Introduction Chronic hyperglycemia is caused by diabetes mellitus-committed genital morphophysiology, and oxidative stress is one of the main factors involved in this process. Alpha lipoic acid (ALA) can prevent metabolic and morphological changes in diabetic individuals. Objectives In present study, we evaluated the effects of regular ALA consu
Int. braz j urol.. Publicado em: 02/09/2019
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3. Gum arabic and red propolis protecteting colorectal preneoplastic lesions in a rat model of azoxymethane
Abstract Purpose: To evaluate red propolis, gum arabic and L-lysine activity on colorectal preneoplastic lesions induced by azoxymethane (AOM). Methods: The study featured 4 control groups (I-IV) and 4 experimental groups (V-VIII), totaling 48 rats. Once a week for 2 weeks, animals on control groups received saline, while animals in experimental groups re
Acta Cir. Bras.. Publicado em: 28/02/2019
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4. Baicalein alleviates tubular-interstitial nephritis in vivo and in vitro by down-regulating NF-κB and MAPK pathways
Tubular-interstitial nephritis (TIN) is characterized by tubular cell damage and inflammatory lesions of kidneys. Baicalein (BAI) is a flavonoid compound found in the roots of Scutellaria baicalensis Georgi. The present study was undertaken to explore the anti-inflammatory and anti-oxidative effects of BAI on TIN patients and a lipopolysaccharide (LPS)-induc
Braz J Med Biol Res. Publicado em: 06/08/2018
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5. Increased salivary aldehyde dehydrogenase 1 in non-reticular oral lichen planus
Abstract: Background: Oral lichen planus is a potentially malignant disorder. One of the malignant transformation markers is cancer stem cells. One of the proposed marker for the detection of cancer stem cells's in head and neck cancer is aldehyde dehydrogenase. Recently it is shown that aldehyde dehydrogenase 1 expression in tissue samples is associated wi
An. Bras. Dermatol.. Publicado em: 2017-03
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6. The role of oxidative stress in streptozotocin-induced diabetic nephropathy in rats
ABSTRACT Objective The objective of this study was to evaluate the role of oxidative stress in an experimental model of streptozotocin-induced diabetic nephropathy in rats. Materials and methods Wistar, adult, male rats were used in the study. Animals were divided in the following groups: Citrate (control, citrate buffer 0.01M, pH 4.2 was administrated i
Arch. Endocrinol. Metab.. Publicado em: 25/08/2016
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7. Extract of the Bark of Bathysa cuspidataAttenuates the Development of Chemically-Induced Preneoplastic Colorectal Lesions in Rats
ABSTRACTThe aim of this study was to investigate the effect of the bark extractBathysa cuspidata on chemically induced preneoplastic colorectal lesions in Wistar rats. Forty male rats were randomly divided into four groups (n = 10 each): saline (control group, oral administration of saline solution 0.9%); dimethylsulfoxide (DMSO, vehicle control), B200 (trea
Braz. arch. biol. technol.. Publicado em: 2015-10
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8. Low-intensity red and infrared laser effects at high fluences on Escherichia coli cultures
Semiconductor laser devices are readily available and practical radiation sources providing wavelength tenability and high monochromaticity. Low-intensity red and near-infrared lasers are considered safe for use in clinical applications. However, adverse effects can occur via free radical generation, and the biological effects of these lasers from unusually
Braz J Med Biol Res. Publicado em: 28/07/2015
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9. Induction of resistance to Pyricularia oryzae in wheat by acibenzolar-S-methyl, ethylene and jasmonic acid
This study investigated the effects of acibenzolar-S-methyl (ASM), ethylene (ET) and jasmonic acid (JA) on the resistance of two wheat cultivars (BRS-229 and BR-18) to infection by Pyricularia oryzae. The treatments included spraying plants with ASM (300 mg L-1), ET (0.5 mM), JA (0.1 mM) and distilled water (control) 48 h before inoculation with P. oryzae. M
Trop. plant pathol.. Publicado em: 2014-06
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10. The role of oxytocin in cardiovascular regulation
Studies of body volume expansion have indicated that lesions of the anteroventral third ventricle and median eminence block the release of atrial natriuretic peptide (ANP) into the circulation. Detailed analysis of the lesions showed that activation of oxytocin (OT)-ergic neurons is responsible for ANP release, and it has become clear that activation of neur
Braz J Med Biol Res. Publicado em: 18/03/2014
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11. DNA repair diseases: what do they tell us about cancer and aging?
The discovery of DNA repair defects in human syndromes, initially in xeroderma pigmentosum (XP) but later in many others, led to striking observations on the association of molecular defects and patients' clinical phenotypes. For example, patients with syndromes resulting from defective nucleotide excision repair (NER) or translesion synthesis (TLS) present
Genet. Mol. Biol.. Publicado em: 2014
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12. Use of defatted flaxseed meal reduces precancerous colon lesions in C57BL/6 mice
PURPOSE: To investigate the hemopreventive effect of defatted flaxseed meal in C57BL/6 mice after induction of precancerous colon lesions with 1.2-dimethylhydrazine (DMH). METHODS: Thirty-six 12-week-old C57BL/6 mice were divided into three treatment groups(n=12 in each group): (1) diet with 10% defatted flaxseed meal; (2) diet with defatted flaxseed meal an
Acta Cir. Bras.. Publicado em: 2013-08