Oxidative Modulation
Mostrando 1-12 de 95 artigos, teses e dissertações.
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1. Dexmedetomidine Leads to the Mitigation of Myocardial Ischemia/Reperfusion-Induced Acute Lung Injury in Diabetic Rats Via Modulation of Hypoxia-Inducible Factor-1α
ABSTRACT Introduction: The objective of this study is to investigate the protective mechanism of dexmedetomidine (Dex) in myocardial ischemia/reperfusion (MIR)-induced acute lung injury (ALI) of diabetic rats by inhibiting hypoxia-inducible factor-1α (HIF-1α). Methods: Initially, healthy male Sprague Dawley rats were treated with streptozocin to induce d
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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2. Salt stress alleviation by seed priming with silicon in lettuce seedlings: an approach based on enhancing antioxidant responses
ABSTRACT Seed germination and seedling growth are the stages most sensitive to salt stress, which can induce ion-specific effects and oxidative stress. Although silicon (Si) has been known to improve plant defense systems against stressful-conditions, little is known about seed priming with Si and mechanisms of Si-mediated alleviation of salt stress in seedl
Bragantia. Publicado em: 2020-03
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3. EFFECTS OF AEROBIC EXERCISE TRAINING ON OXIDATIVE STRESS IN THE SKELETAL MUSCLES OF OBESE RATS
RESUMO Introdução Obesidade é uma desordem metabólica complexa e multifatorial, caracterizada pelo acúmulo de gordura corporal. O exercício físico tem a capacidade de aumentar o gasto energético e promover efeito reparador por meio da modulação das defesas antioxidantes endógenas. Objetivo Avaliar os efeitos da dieta hiperlipídica (DHL) sobre
Rev Bras Med Esporte. Publicado em: 07/10/2019
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4. Time-course of health-related adaptations in response to combined training in hypertensive elderly: immune and autonomic modulation interactions
Abstract Aims: This article is a methodological description of a randomized clinical trial (ClinicalTrials.gov U1111-1181-4455) aiming to evaluate the time-course (monthly) and associations between blood pressure changes and other health-related adaptations in response to exercise training in hypertensive elderly. Methods: The patients will be randomized
Motriz: rev. educ. fis.. Publicado em: 23/11/2018
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5. Combined GSTM1 and GSTT1 null genotypes are strong risk factors for atherogenesis in a Serbian population
Abstract Oxidative stress (OS) plays an important role in atherogenesis and since glutathione S-transferases (GSTs) provide protection against OS, we have tested the hypothesis that deletion polymorphisms in two GSTs (GSTM1 and GSTT1) may affect the risk of developing atherosclerosis. A total of 382 individuals (200 patients with atherosclerosis and 182 heal
Genet. Mol. Biol.. Publicado em: 2018-03
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6. Effects of N-acetylcysteine on spinal cord oxidative stress biomarkers in rats with neuropathic pain
N-acetylcysteine (NAC) inhibits nociceptive transmission. This effect has been associated partly with its antioxidant properties. However, the effect of NAC on the levels of lipid hydroperoxides (a pro-oxidant marker), content of ascorbic acid (a key antioxidant molecule of nervous tissue) and total antioxidant capacity (TAC) is unknown. Thus, our study asse
Braz J Med Biol Res. Publicado em: 19/10/2017
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7. Grape juice increases the BDNF levels but not alter the S100B levels in hippocampus and frontal cortex from male Wistar Rats
ABSTRACT Several studies have shown that a high consumption of vegetables and fruits is consistently associated with a low risk of oxidative stress-induced diseases, which includes some degenerative diseases such as amyotrophic lateral sclerosis, Alzheimer and Parkinson. Therefore, the objective of this study is to verify the effects of conventional and orga
An. Acad. Bras. Ciênc.. Publicado em: 02/03/2017
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8. Caryocar brasiliense camb protects against genomic and oxidative damage in urethane-induced lung carcinogenesis
The antioxidant effects of Caryocar brasiliense Camb, commonly known as the pequi fruit, have not been evaluated to determine their protective effects against oxidative damage in lung carcinogenesis. In the present study, we evaluated the role of pequi fruit against urethane-induced DNA damage and oxidative stress in forty 8-12 week old male BALB/C mice. An
Braz J Med Biol Res. Publicado em: 21/07/2015
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9. Ozone oxidative preconditioning protects the rat kidney from reperfusion injury via modulation of the TLR4-NF-κB pathway
PURPOSE:To investigate the protective effects of ozone oxidative preconditioning (OzoneOP) were associated with the modulation of TLR4-NF-κB pathway.METHODS: Thirty six rats were subjected to 45 min of renal ischemia, with or without treatment with OzoneOP (1 mg/kg). Blood samples were collected for the detection of blood urea nitrogen and creatinine levels
Acta Cir. Bras.. Publicado em: 2015-01
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10. Combined aliskiren and L-arginine treatment has antihypertensive effects and prevents vascular endothelial dysfunction in a model of renovascular hypertension
Angiotensin II is a key player in the pathogenesis of renovascular hypertension, a condition associated with endothelial dysfunction. We investigated aliskiren (ALSK) and L-arginine treatment both alone and in combination on blood pressure (BP), and vascular reactivity in aortic rings. Hypertension was induced in 40 male Wistar rats by clipping the left rena
Braz J Med Biol Res. Publicado em: 24/10/2014
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11. Nutraceutical preconditioning with arginine and oil mixes. Effects on inflammatory mediators, oxidative stress and lipid profile in patients undergoing radical prostatectomy
PURPOSE: To investigate whether there is any effect resulting from preconditioning with nutraceutical supplementation containing arginine and oil mixes with high ω9:ω6 ratio and low ω6:ω3 ratio containing EPA and DHA, ALA fatty acids on inflammatory mediators, antioxidant and lipid profile modulation in surgical trauma.METHODS:Twenty-six men scheduled fo
Acta Cir. Bras.. Publicado em: 2014-08
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12. Manuka honey protects middle-aged rats from oxidative damage
OBJECTIVE: This study aimed to determine the effect of manuka honey on the oxidative status of middle-aged rats. METHOD: Twenty-four male Sprague-Dawley rats were divided into young (2 months) and middle-aged (9 months) groups. They were further divided into two groups each, which were either fed with plain water (control) or supplemented with 2.5 g/kg bo
Clinics. Publicado em: 2013-11