Oxidized Ldl
Mostrando 1-12 de 150 artigos, teses e dissertações.
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1. Rapamycin and Paclitaxel Affect Human Aortic Smooth Muscle Cells-Derived Foam Cells Viability and Proliferation
Abstract Introduction: Drug-eluting stents (DES) coated with rapamycin or paclitaxel as antiproliferative substances significantly reduced the incidence of clinical restenosis and had fewer side effects after percutaneous coronary intervention. However, DES coated with rapamycin or paclitaxel still cause restenosis due to abnormal tissue growth which remain
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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2. Evaluation of Serum Levels of Inflammation, Fibrinolysis and Oxidative Stress Markers in Coronary Artery Disease Prediction: A Cross-Sectional Study
Resumo Fundamento: A doença arterial coronariana (DAC) tem sido há muito reconhecida como um problema de saúde global. Inflamação, fibrinólise e estresse oxidativo desempenham um papel importante no acometimento das placas, levando à DAC. Os marcadores que refletem esse mecanismo fisiopatológico podem ter valor prognóstico. Objetivo: Estimar as co
Arq. Bras. Cardiol.. Publicado em: 29/08/2019
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3. Oxidized and electronegative low-density lipoprotein as potential biomarkers of cardiovascular risk in obese adolescents
OBJECTIVES: To evaluate biomarkers associated with early cardiometabolic risk in obese adolescents. METHODS: This cross-sectional study included 137 adolescents of both sexes aged 10 to 19 years divided into a normal weight group (NW) (n=69) and an obese group (OB) (n=68). RESULTS: As expected, obesity showed positive associations with homeostatic model a
Clinics. Publicado em: 18/10/2018
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4. Peripheral brain-derived neurotrophic factor is related to cardiovascular risk factors in active and inactive elderly men
Regular exercise plays an important preventive and therapeutic role in heart and vascular diseases, and beneficially affects brain function. In blood, the effects of exercise appear to be very complex and could include protection of vascular endothelial cells via neurotrophic factors and decreased oxidative stress. The purpose of this study was to identify t
Braz J Med Biol Res. Publicado em: 20/06/2016
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5. Hypolipidemic and antiatherogenic effects of Cynara scolymus in cholesterol-fed rats
ABSTRACT Cynara scolymus L., Asteraceae, are traditionally used to treat dyspepsia. This study evaluated the hypolipidemic and antiatherogenic effects of an aqueous extract prepared from the leaves of C. scolymus in rat's model. Hypercholesterolemic rats (1% cholesterol and 0.5% cholic acid for 15 days) were treated (0.5 ml/200 g) with extract of C. scolymus
Rev. bras. farmacogn.. Publicado em: 2016-04
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6. Serum total oxidant/anti-oxidant status, ischemia-modified albumin and oxidized-low density lipoprotein levels in patients with vitamin D deficiency
Objective Oxidative damage may be responsible for the pathogenesis and complications of many diseases. Vitamin D deficiency has been suggested as a potential mediator of various extra-skeletal pathologies. However, there are limited data on anti-oxidant properties of vitamin D.Materials and methods Forty-one subjects with vitamin D deficiency and 30 healthy
Arch. Endocrinol. Metab.. Publicado em: 2015-08
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7. Associations between CD36 gene polymorphisms and susceptibility to coronary artery heart disease
Associations between polymorphisms of the CD36 gene and susceptibility to coronary artery heart disease (CHD) are not clear. We assessed allele frequencies and genotype distributions of CD36 gene polymorphisms in 112 CHD patients and 129 control patients using semi-quantitative polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFL
Braz J Med Biol Res. Publicado em: 08/08/2014
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8. Ox-LDL increases OX40L in endothelial cells through a LOX-1-dependent mechanism
Oxidative low-density lipoprotein (Ox-LDL) is a key risk factor for the development of atherosclerosis, and it can stimulate the expression of a variety of inflammatory signals. As a new and highly sensitive inflammation index, OX40L may be a key to understanding the mechanisms that regulate interactions between cells within the vessel wall and inflammatory
Braz J Med Biol Res. Publicado em: 19/09/2013
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9. ASSOCIAÇÃO ENTRE O POLIMORFISMO +3954 DO GENE DA INTERLEUCINA-1 BETA, OBESIDADE, LDL-OXIDADO E SEU POTENCIAL EFEITO LIPOTÓXICO / ASSOCIATION BETWEEN INTERLEUKIN-1 BETA GENE, OBESITY, LDL-OXIDADE AND ITS LIPOTOXICITY EFFECT POTENCIAL
A obesidade é um inflamação sistêmica de baixo grau associado a elevada liberação de moléculas pró-inflamatórias pelo tecido adiposo. O aumento da adiposidade resulta em necrose tecidual e liberação de ácidos graxos, a partir dos adipócitos, que tendem a se acumular em outros tecidos corporais causando um fenômeno conhecido como lipotoxicidade.
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/03/2012
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10. Association of postalimentary lipemia with atherosclerotic manifestations
We identified different lipemic and metabolic responses after the ingestion of a standardized meal by healthy adults and related them to atherosclerotic markers. Samples from 60 normolipidemic adults were collected before and after a liquid meal (40 g fat/m² body surface) at 0, 2, 4, 6, and 8 h for measurements of lipids, free fatty acids (FFA), insulin, ch
Braz J Med Biol Res. Publicado em: 2012-11
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11. Paradoxical effect of a pequi oil-rich diet on the development of atherosclerosis: balance between antioxidant and hyperlipidemic properties
Pequi is the fruit of Caryocar brasiliense and its oil has a high concentration of monounsaturated and saturated fatty acids, which are anti- and pro-atherogenic agents, respectively, and of carotenoids, which give it antioxidant properties. Our objective was to study the effect of the intake of a cholesterol-rich diet supplemented with pequi oil, compared t
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-07
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12. A esplenectomia aumenta as lesões ateroscleróticas em camundongos deficientes em apoproteína E submetidos a uma dieta aterogênica
Atherosclerosis is an inflammatory immune disease associated with lipid accumulation in the intima layer of arteries. The spleen plays an important immune function, but its influence in development of atherosclerosis remains unclear. Evaluation of the role of the spleen in atherosclerosis is justified due to the high frequency of total splenectomies and the
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/08/2011