Oxldl Autoantibodies
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Association of postalimentary lipemia with atherosclerotic manifestations
We identified different lipemic and metabolic responses after the ingestion of a standardized meal by healthy adults and related them to atherosclerotic markers. Samples from 60 normolipidemic adults were collected before and after a liquid meal (40 g fat/m² body surface) at 0, 2, 4, 6, and 8 h for measurements of lipids, free fatty acids (FFA), insulin, ch
Braz J Med Biol Res. Publicado em: 2012-11
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2. Modificações oxidativas de lipoproteínas de baixa densidade e seus anticorpos : associação com componentes do transporte reverso de colesterol e com a aterosclerose carotídea em adultos sem doença aterosclerótica estabelecida / Oxidative modification of plasma low density lipoproteins and their antibodies : association with the reverse cholesterol transport and carotid atherosclerosis in adults without established aterosclerotic disease
Cardiovascular disease (DCV) is the most common cause of death on western societies, affecting both sexes, with atherosclerosis being the most important underlying pathology. Atherosclerosis is accepted worldwide as an immuneinflammatory disease, in which the participation of the immune system is crucial for the beginning of endothelial dysfunction, fatty st
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/05/2011
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3. Avaliação do modelo de hamster para detecção das alterações lipídicas e cardiotoxicidade associadas à terapia contra o vírus da imunodeficiência humana / Evaluation of the hamster model for the detection of lipidic and cardiotoxicity alterations associated to therapy against human immunodeficiency virus
With the introduction of a new antiretroviral class use, integrants of highly active anti-retroviral therapy (HAART) for the treatment of infections by human immunodeficiency virus, several side effects started to be described.To establish an animal model for the study of these side effects, was chosen specie that have similarities in the lipidic profile and
Publicado em: 2010
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4. Enzymes that hydrolyze adenine nucleotides of patients with different cholesterol levels and inflammatory processes / HIDRÓLISE DE NUCLEOTÍDEOS DE ADENINA EM PLAQUETAS DE PACIENTES COM DIFERENTES NÍVEIS DE COLESTEROL E SUA RELAÇÃO COM O PROCESSO INFLAMATÓRIO
A atividade da NTPDase (EC 3.6.1.5, apyrase, CD39) foi verificada em plaquetas de pacientes com diferentes níveis de colesterol. Uma possível associação entre os níveis de colesterol e os marcadores inflamatórios como LDL oxidado (oxLDL), proteína C reativa ultrasensível (hsCRP) e anticopos anti-LDL oxidado (Anti-oxLDL) foi investigado. Os seguintes
Publicado em: 2006
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5. Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis.
Atherosclerotic lesions contain oxidized LDL (OxLDL), immunoglobulins, and immune-competent cells. Low levels of circulating autoantibodies against malondialdehyde (MDA)-modified lysine, an epitope of OxLDL, occur in several species, and immune complexes between such autoantibodies and OxLDL are present in lesions. To study the potential role of autoantibodi
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6. Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid–protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins
We recently cloned monoclonal IgM autoantibodies which bind to epitopes of oxidized low-density lipoprotein (OxLDL) from apoE-deficient mice (EO– autoantibodies). We now demonstrate that those EO– autoantibodies that were originally selected for binding to copper-oxidized low-density lipoproteins (CuOx-LDL), also bound both to the oxidized protein and to
American Society for Clinical Investigation.
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7. Preparation of a Human Standard for Determination of the Levels of Antibodies to Oxidatively Modified Low-Density Lipoproteins
As part of our ongoing effort to develop a standardized competitive enzyme immunoassay for human autoantibodies to oxidized low-density lipoprotein (oxLDL), we have generated a reference human antibody standard and revised some of the conditions of the assay. The preparation of the standard involved purification of human anti-oxLDL antibodies by affinity chr
American Society for Microbiology.
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8. Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: Evidence that oxidation-specific epitopes mediate macrophage recognition
Apoptosis is recognized as important for normal cellular homeostasis in multicellular organisms. Although there have been great advances in our knowledge of the molecular events regulating apoptosis, much less is known about the receptors on phagocytes responsible for apoptotic cell recognition and phagocytosis or the ligands on apoptotic cells mediating suc
The National Academy of Sciences.