Parasite
Mostrando 1-12 de 4321 artigos, teses e dissertações.
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1. Tandem Synthesis of Furanaphthoquinones via Enamines and Evaluation of Their Antiparasitic Effects against Trypanosoma cruzi
Furanaphthoquinones are well known in medicinal chemistry for exhibiting relevant structural heterogeneity and bioactivities. In this work, it was synthesized a series of furanaphthoquinones through a tandem reaction between lawsone (8) and cyclic ketones in the presence of morpholine. This strategy provides an efficient and general method for synthesizing f
Journal of the Brazilian Chemical Society. Publicado em: 2022
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2. Revisiting the History of Chagas Disease: "Live to tell"
Abstract In 1907, Carlos Chagas was designated to fight paludism in the Rio das Velhas region along the Central do Brasil railroad. During his field research, Chagas discovered a hematophagous insect ( Panstrongylus megitus ) carrying a new trypanosomatide, which he named Trypanosoma cruzi . On April 14th, 1909, he found the same parasite in the blood of a f
International Journal of Cardiovascular Sciences. Publicado em: 2022
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3. Molecular Modeling and Chemical Synthesis of New Safrol Oxime Ether Derivatives
Leishmaniasis, a neglected tropical disease with a high worldwide incidence, is considered a public health issue in Minas Gerais and Brazil, with a high degree of morbidity, not to mention the lack of therapeutic arsenal. The cysteine protease (rCPB2.8) and cyclin dependent kinase (CRK3), important enzymes for the parasite’s feasibility, were the targets c
J. Braz. Chem. Soc.. Publicado em: 2021-07
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4. Agradecimentos aos Pareceristas ad hoc do volume 18 (ano 2020)
According to the World Health Organization (WHO), Chagas disease (CD), whose etiological agent is the Trypanosoma cruzi (T. cruzi) parasite, affects about eight million people, mainly in Latin America. The cruzain enzyme is highlighted among the main biological targets, since it is the most abundant of the cysteine protease class from T. cruzi and is involve
Trab. educ. saúde. Publicado em: 2021-01
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5. Molecular Modelling Study of Heteroarylamide/Sulfonamide Compounds with Antitrypanosomal Activity
According to the World Health Organization (WHO), Chagas disease (CD), whose etiological agent is the Trypanosoma cruzi (T. cruzi) parasite, affects about eight million people, mainly in Latin America. The cruzain enzyme is highlighted among the main biological targets, since it is the most abundant of the cysteine protease class from T. cruzi and is involve
J. Braz. Chem. Soc.. Publicado em: 2021-01
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6. Response of grey slug to entomopathogenic nematodes
ABSTRACT Biological control using entomopathogenic nematodes (EPNs) is known as an ecofriendly strategy in integrated pest management. The terrestrial slug Parmacella ibera is a major pest of vegetables and citrus trees in north of Iran. The heavy costs and environmental concerns of synthetic molluscicides led the study to use EPNs, against the slug P. ibera
Bragantia. Publicado em: 2020-12
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7. RESENHA DE ESSE AIRES, ORGANIZADO POR ABEL BARROS BAPTISTA, CLARA ROWLAND E PEDRO MEIRA MONTEIRO
ABSTRACT With the aim to determine the prevalence and mean parasite intensity in Oncorhynchus mykiss, 120 specimens were analyzed between April and September 2018. The cavity analysis was done by visual inspection, scraping of mucus, and extraction of the branchial arches. In the evisceration process, the intestine, the liver, and the kidney were separated,
Machado Assis Linha. Publicado em: 2020-12
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8. Parasitos em trutas-arco-íris (Oncorhynchus mykiss) criadas em sistema intensivo na região serrana de Santa Catarina, Brasil
ABSTRACT With the aim to determine the prevalence and mean parasite intensity in Oncorhynchus mykiss, 120 specimens were analyzed between April and September 2018. The cavity analysis was done by visual inspection, scraping of mucus, and extraction of the branchial arches. In the evisceration process, the intestine, the liver, and the kidney were separated,
Arq. Bras. Med. Vet. Zootec.. Publicado em: 2020-12
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9. Compact Ultra-Wide-Band HI Monopole Antenna Loaded with C-Shaped Parasitic Elements for DVB-T and LTE Applications
Abstract In this work, a compact ultra-wide-band microstrip antenna loaded with C-shaped parasitic elements, for Digital Video Broadcasting - Terrestrial (DVB-T) and LTE 450 / 700 signal reception, is designed and presented. The proposed antenna is named “HI Monopole”, and its geometry has been designed to be simple, lightweight, and compact. Fabrication
J. Microw. Optoelectron. Electromagn. Appl.. Publicado em: 2020-09
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10. Identification of Leishmania species by high-resolution DNA dissociation in cases of American cutaneous leishmaniasis,
Abstract Background American cutaneous leishmaniasis is an infectious dermatosis caused by protozoa of the genus Leishmania, which comprises a broad spectrum of clinical manifestations depending on the parasite species involved in the infections and the immunogenetic response of the host. The use of techniques for amplification of the parasites DNA based on
An. Bras. Dermatol.. Publicado em: 2020-08
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11. Synthesis, Antileishmanial Activity and Spin Labeling EPR Studies of Novel β-Carboline-Oxazoline and β-Carboline-Dihydrooxazine Derivatives
A series of novel 1-(substituted-phenyl)-3-(4,5-dihydro-1,3-oxazol-2-yl)-9H-β-carboline (8a-8i) and 1-(substituted-phenyl)-3-(5,6-dihydro-4H-1,3-oxazin-2-yl)-9H-β-carboline (9a-9h) derivatives, as well as their respective N-(chloroalkyl)-1-(substituted-phenyl)-9H-β-carboline-3-carboxamide precursors (6a-6i and 7a-7h), were synthesized and evaluated for th
J. Braz. Chem. Soc.. Publicado em: 2020-06
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12. Viral metagenomics performed in patients with acute febrile syndrome during Toxoplasma gondii outbreak in south Brazil
ABSTRACT Toxoplasmosis is a zoonotic infection caused by the protozoan parasite Toxoplasma gondii. The infection is widely disseminated in the human population and is usually benign or asymptomatic. Systemic T. gondii infection presents risks for pregnant women and AIDS patients. Although rare, T. gondii can cause outbreaks in urban centers. The origin of th
Braz J Infect Dis. Publicado em: 2020-06