Parasitic Strain
Mostrando 1-12 de 69 artigos, teses e dissertações.
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1. Evaluation of melanin production by Sporothrix luriei
There is a paucity of studies on the cell biology of Sporothrix luriei, the less common of the pathogenic Sporothrix species worldwide. The production of DHN-melanin, eumelanin, and pyomelanin were evaluated on the mycelial and yeast forms of the S. luriei ATCC 18616 strain. The mycelial form of this species produced only pyomelanin, which protected the fung
Mem. Inst. Oswaldo Cruz. Publicado em: 2018-01
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2. EVALUATION OF THE THERAPEUTIC EFFICACY OF LEVAMISOLE HYDROCHLORIDE ON THIRD-STAGE LARVAE OF Lagochilascaris minor IN EXPERIMENTALLY INFECTED MICE
Lagochilascariosis, a disease caused by Lagochilascaris minor, affects the neck, sinuses, tonsils, lungs, the sacral region, dental alveoli, eyeballs and the central nervous system of humans. A cycle of autoinfection may occur in human host tissues characterized by the presence of eggs, larvae and adult worms. This peculiarity of the cycle hinders therapy, s
Rev. Inst. Med. trop. S. Paulo. Publicado em: 24/05/2016
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3. Mir-190b negatively contributes to the Trypanosoma cruzi- infected cell survival by repressing PTEN protein expression
Chagas disease, which is caused by the intracellular protozoanTrypanosoma cruzi, is a serious health problem in Latin America. The heart is one of the major organs affected by this parasitic infection. The pathogenesis of tissue remodelling, particularly regarding cardiomyocyte behaviour after parasite infection, and the molecular mechanisms that occur immed
Mem. Inst. Oswaldo Cruz. Publicado em: 2015-12
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4. An efficient formulation for linear and geometric non-linear membrane elements
Utilizing the straingradient notation process and the free formulation, an efficient way of constructing membrane elements will be proposed. This strategy can be utilized for linear and geometric non-linear problems. In the suggested formulation, the optimization constraints of insensitivity to distortion, rotational invariance and not having parasitic shear
Lat. Am. j. solids struct.. Publicado em: 2014-11
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5. Planejamento de inibidores das enzimas diidroorotato desidrogenase de Trypanosoma cruzi e Leishmania major / Design of inhibitors for dihydroorotate dehydrogenase from Trypanosoma cruzi and Leishmania major
Dihydroorotate dehydrogenase (DHODH) catalyses the conversion of dihydroorote to orotate, the fourth step and only redox reaction in the de novo pyrimidine biosynthetic pathway. DHODH has been exploited as a validated target for therapy against proliferative and parasitic diseases, and in particular, has been considered to be an attractive target for drug de
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/04/2012
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6. Reduced genetic variability within coding and non-coding regions of the echinococcus multilocularis genome
Echinococcus multilocularis, a vulpine intestinal tapeworm, is the causative agent of alveolar echinococosis in humans, one of the most severe and lethal parasitic infections in man. To date, there is very little knowledge about the genetical polymorphism of this parasite. To assess sequence polymorphism, we analysed a sample of 33 E. multilocularis isolates
Publicado em: 2011
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7. Characterization of the Leishmania (Leishmania) amazonensis genomic region containing the META 1 gene. / Caracterização da região genômica META 1 de Leishmania (Leishmania) amazonensis e comparação com a região ortóloga de L. (L.) major.
The characterization of coding sequences in the vicinity of the META 1 gene allowed the identification of some genes preferentially expressed in L. (L.) amazonensis infective stages. One of the identified transcripts presents a distinct pattern of expression with higher levels of mRNA in amastigotes. This gene was named LaLRR17 since it encodes a 72 kDa prot
Publicado em: 2008
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8. Evaluation of the treatment with dehydroepiandrosterone in males and females Wistar rats during experimental Chagasdisease. / Avaliação do tratamento com dehidroepiandrosterona em ratos Wistarmachos e fêmeas durante a infecção chagásica experimental
Dehidroepiandrosterone (DHEA) has been considered for many researchers as the steroid of multiple functions. The immunologic stimulation triggered by DHEA has been demonstrated not only in animal models but also in humans. DHEA has been used as an alternative therapy to up-modulate immune response in host bearing viral, bacterial and parasitic infections. Th
Publicado em: 2007
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9. The study of ionizing radiation as a tool for select promastigotes forms of Leishmania amazonensis, and the immunological response in experimental models / Estudo do uso da radiação ionizante como ferramenta de seleção de formas promastigotas metacíclicas de Leishmania amazonensis e a indução de resposta imunológica em modelos experimentais
Actually, millions of people around the globe are under the risk of infection by a protozoan transmitted by a bit of a sand fly. This parasite is a Leishmania spp. This causes a wide spectrum disease, since a coetaneous disease to a visceral one. The coetaneous form is the major clinical manifestation (above 90%). The ionizing radiation, produced in a 60Co f
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/11/2006
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10. O EFEITO DA PRESSÃO SELETIVA COM PRAZIQUANTEL NA DIVERSIDADE GENÉTICA DA CEPA LE DE Schistosoma mansoni.
Schistosomiasis is one of the parasitic diseases that make a considerable impact upon public health worldwide. In Brazil, it is caused by the digenetic trematode Schistosoma mansoni. The most important schistosomiasis control measure is a large-scale specific chemotherapy. Currently, the drug chosen for schistosomiasis treatment is praziquantel (PZQ). Althou
Publicado em: 2005
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11. Fibrose e outras lesÃes hepÃticas em camundongos isogÃnicos ("inbred") desnutridos e eutrÃficos, infectados com Schistosoma mansoni / Fibrosis and other hepatic lesions in undernourished and well-nourished inbred mice infected with
In chronic schistosomiasis mansoni, periovular granulomas and periportal fibrosis are the most important hepatic lesions, besides vascular changes that lead to hypertension within the portal venous system. Well-nourished Swiss outbred mice infected with Schistosoma mansoni develop lesions that mimick those found in advanced clinical forms of human intestinal
Publicado em: 2004
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12. "Toxoplasma gondii vs radiação ionizante: Estudo da imunidade intestinal em camundongos C57Bl/6j experimentalmente vacinados com taquizoítos irradiados" / Toxoplasma gondii vs ionizing radiation: Intestinal immunity induced in C57bl/6j mice by irradiated tachyzoites
We study the oral route for the development of a vaccine for toxoplasmosis, using parasites irradiated with 60 Cobalt, as an alternative for vaccine development to this worldwide parasitic infection. We evaluated the development of immunity at serum or mucosal levels, and their efficiency in protect the mice against challenge with oral cysts of the ME-49 str
Publicado em: 2004