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Mostrando 1-12 de 1452 artigos, teses e dissertações.
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1. Polypyridyl Ruthenium Complexes: Novel DNA-Intercalating Agents against Human Breast Tumor
This paper describes a new series of four DNA-intercalating agents with promising anticancer activities, based on ruthenium(II) with the planar ligand dpqQX (dpqQX = dipyrido[3,2-a:2',3'-c]quinoxaline[2,3-b]quinoxaline). The complexes identified as trans-[RuCl2(dppb)(dpqQX)], cis-[RuCl2(dppb)(dpqQX)], ct-[RuCl(CO)(dppb)(dpqQX)]PF6 and ct-[RuCl2(PPh3)2(dpqQX)
J. Braz. Chem. Soc.. Publicado em: 2017-10
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2. Isolation and characterization of flavanols from Anthocephalus cadamba and evaluation of their antioxidant, antigenotoxic, cytotoxic and COX-2 inhibitory activities
ABSTRACT In search of lead molecules for use in disease prevention and as food additive from natural sources, two flavanols were isolated from leaves of Anthocephalus cadamba (Roxb.) Miq., Rubiaceae. Their structures were established as 6-hydroxycoumarin-(4"→8)-(-)-epicatechin and 6-hydroxycoumarin-(4"→8)-(-)-epicatechin-(4→6‴)-(-)-epicatechin on the
Rev. bras. farmacogn.. Publicado em: 2016-08
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3. Antioxidant, DNA damage protective, neuroprotective, and α-glucosidase inhibitory activities of a flavonoid glycoside from leaves of Garcinia gracilis
Abstract The leaves of Garcinia gracilis Pierre, Clusiaceae, have been used as flavouring materials in food, with no previous reports of their biological activities and chemical constituents. In this study, the methanolic extract of G. gracilis afforded three compounds namely apigenin-8-C-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (1), 5-hydroxymethyl
Rev. bras. farmacogn.. Publicado em: 2016-06
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4. Caracterização molecular e análise filogenética de sequências do antígeno de superfície 3 (SAG3) em isolados indianos (CHENNAI E IZATNAGAR) de Toxoplasma gondii
Contexto e objetivo. A caracterização molecular de isolados indianos de Toxoplasma gondii é importante para a investigação de variações genéticas existentes entre cepas do parasito em diferentes locos gênicos. Delineamento e disposição. A presente comunicação realizou a clonagem e o sequenciamento dos 1158 pares de base correspondendo à totali
Rev. Inst. Med. trop. S. Paulo. Publicado em: 2015-06
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5. Fish diet composition in permanent and semi-permanent pools in tropical wetlands of the Yucatan Peninsula
We compared fish diet composition between permanent (P) and semi-permanent (SP) pools in Petenes Biosphere Reserve (PBR), Campeche. A total of 445 gut contents were examined to determine stomach relative fullness (RF), fish diet as index of niche breadth (INB) and diet overlap. In SP pools, species showed a RF of 1.66 (57.20 % empty stomachs) whereas in P po
Neotrop. ichthyol.. Publicado em: 2013
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6. BalanÃo eletrolÃtico da raÃÃo de suÃnos em fase inicial submetidos à condiÃÃo de conforto e estresse tÃrmico / Electrolyte balance in the diet of pigs in initial phase subject to the condition of confort and thermal stress
Este trabalho teve por objetivo estudar o balanÃo eletrolÃtico de raÃÃes sobre o metabolismo do balanÃo de nitrogÃnio, parÃmetros sanguÃneos, pH urinÃrio e resposta fisiolÃgica de suÃnos machos castrados na fase inicial, em condiÃÃo de estresse e conforto tÃrmico. Para o experimento foram utilizados 32 suÃnos machos castrados em fase inicial,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/02/2012
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7. Construção de sistemas bacterianos para a detecção de metais pesados em amostras ambientais. / Construction of bacterial systems for the detection of heavy metals in environmental samples.
Aiming at the construction of three bacterial biosensors for metals mercury, arsenic and lead, Cupriavidus metallidurans CH34 was chosen to obtain the DNA fragments (by PCR) corresponding to operons mer, ars and pbr. The fragments were inserted upstream of the EGFP gene, in plasmid pBB-EGFP, getting three new plasmids: pGHg, pGAs and pGPb. They were cloned i
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/01/2012
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8. Expression of phenazine biosynthetic genes during the arbuscular mycorrhizal symbiosis of Glomus intraradices
To explore the molecular mechanisms that prevail during the establishment of the arbuscular mycorrhiza symbiosis involving the genus Glomus, we transcriptionally analysed spores of Glomus intraradices BE3 during early hyphal growth. Among 458 transcripts initially identified as being expressed at presymbiotic stages, 20% of sequences had homology to previous
Brazilian Journal of Microbiology. Publicado em: 2012-06
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9. An antimicrobial alkaloid and other metabolites produced by Penicillium sp. An endophytic fungus isolated from Mauritia flexuosa L. f.
The alkaloid glandicoline B (1) and six other compounds: ergosterol (2), brassicasterol (3), ergosterol peroxide (4), cerevisterol (5), mannitol (6) and 1-O-α-D-glucopyranoside (7) were isolated from Penicillium sp. strain PBR.2.2.2, a fungus from Mauritia flexuosa roots. The structures of the isolated metabolites were established by spectral analysis. MeOH
Química Nova. Publicado em: 2012
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10. Neolignans from Licaria chrysophylla and Licaria aurea with DNA topoisomerase II-α inhibitory activity
Seven natural neolignans isolated from Licaria chrysophylla and Licaria aurea along with five semisynthetic derivatives were tested for their inhibitory action on DNA-topoisomerase by relaxation assays on pBR322 plasmid DNA. All compounds tested showed strong inhibition at a concentration of 100 µM, while none showed activity between 5 and 70 µM. These res
Quím. Nova. Publicado em: 2012
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11. Projeto auxiliado por computador de processos indústriais sustentáveis usando os softwares COCO e Scilab
O Projeto Auxiliado por Computador é hoje um procedimento corrente tanto na concepção de novos projetos, quanto no revamp e retrofit dos existentes. Os simuladores de processos estão cada vez mais sofisticados e os bancos de propriedades físico-químicas mais acuradas. Porém mesmo com todos os desenvolvimentos e aperfeiçoamentos dos simuladores, há s
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/07/2011
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12. MHC class I loci of the Bar-Headed goose (Anser indicus)
MHC class I proteins mediate functions in anti-pathogen defense. MHC diversity has already been investigated by many studies in model avian species, but here we chose the bar-headed goose, a worldwide migrant bird, as a non-model avian species. Sequences from exons encoding the peptide-binding region (PBR) of MHC class I molecules were isolated from liver ge
Genetics and Molecular Biology. Publicado em: 2010