Pentose Pathway
Mostrando 1-12 de 206 artigos, teses e dissertações.
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1. Trypanosoma evansi is alike to Trypanosoma brucei brucei in the subcellular localisation of glycolytic enzymes
Trypanosoma evansi, which causes surra, is descended from Trypanosoma brucei brucei, which causes nagana. Although both parasites are presumed to be metabolically similar, insufficient knowledge of T. evansiprecludes a full comparison. Herein, we provide the first report on the subcellular localisation of the glycolytic enzymes in T. evansi, which is a alike
Mem. Inst. Oswaldo Cruz. Publicado em: 29/05/2015
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2. Avaliação experimental do metabolismo energético em dois protocolos de sobrecarga sistólica do ventrículo direito / Experimental evaluation of energy metabolism in two right ventricle systolic overload protocols
Objective: Altered energy metabolism has been identified in myocardial hypertrophy. Some processes are considered beneficial, whereas others are linked to heart failure. The purpose of this study was to compare the activity of three different energy metabolism enzymes in two different protocols of right ventricle (RV) systolic overload in young goats. Method
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/03/2012
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3. Molecular characterization of glucose-6-phosphate dehidrogenase deficiency in patients from the southern brazilian city of Porto Alegre, RS
Glucose-6-phosphate dehydrogenase (G6PDH; EC 1.1.1.49) deficiency is one of the most common human enzymopathies throughout the world. Although most affected individuals are asymptomatic, there is a risk of neonatal jaundice and acute hemolytic anemia which can be triggered by infection, some pharmaceuticals and, in older individuals, eating fava beans. We ch
Publicado em: 2010
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4. Germ band retraction as a landmark in glucose metabolism during Aedes aegypti embryogenesis
Background: The mosquito A. aegypti is vector of dengue and other viruses. New methods of vector control are needed and can be achieved by a better understanding of the life cycle of this insect. Embryogenesis is a part of A. aegypty life cycle that is poorly understood. In insects in general and in mosquitoes in particular energetic metabolism is well studi
Publicado em: 2010
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5. A new approach for potential drug target discovery through in silico metabolic pathway analysis using Trypanosoma cruzi genome information
The current drug options for the treatment of chronic Chagas disease have not been sufficient and high hopes have been placed on the use of genomic data from the human parasite Trypanosoma cruzi to identify new drug targets and develop appropriate treatments for both acute and chronic Chagas disease. However, the lack of a complete assembly of the genomic se
Memórias do Instituto Oswaldo Cruz. Publicado em: 2009-12
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6. The pentose phosphate pathway in Trypanosoma cruzi: a potential target for the chemotherapy of Chagas disease
Trypanosoma cruzi é altamente sensível ao estresse oxidativo causado por espécies reativas do oxigênio. Tripanotiona, o principal protetor do parasita contra o estresse oxidativo, é mantido reduzido pela tripanotiona redutase, pela presença deNADPH; a principal fonte da coenzima reduzida parece ser a via da pentose fosfato. As sete enzimas dessa via es
Anais da Academia Brasileira de Ciências. Publicado em: 2007-12
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7. Differential metabolism of Mycoplasma species as revealed by their genomes
The annotation and comparative analyses of the genomes of Mycoplasma synoviae and Mycoplasma hyopneumonie, as well as of other Mollicutes (a group of bacteria devoid of a rigid cell wall), has set the grounds for a global understanding of their metabolism and infection mechanisms. According to the annotation data, M. synoviae and M. hyopneumoniae are able to
Genetics and Molecular Biology. Publicado em: 2007
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8. The secondary alcohol and aglycone metabolites of doxorubicin alter metabolism of human erythrocytes
Anthracyclines, a class of antitumor drugs widely used for the treatment of solid and hematological malignancies, cause a cumulative dose-dependent cardiac toxicity whose biochemical basis is unclear. Recent studies of the role of the metabolites of anthracyclines, i.e., the alcohol metabolite doxorubicinol and aglycone metabolites, have suggested new hypoth
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-12
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9. Carbohydrate metabolism of Xylella fastidiosa: Detection of glycolytic and pentose phosphate pathway enzymes and cloning and expression of the enolase gene
The objective of this work was to assess the functionality of the glycolytic pathways in the bacterium Xylella fastidiosa. To this effect, the enzymes phosphoglucose isomerase, aldolase, glyceraldehyde-3-phosphate dehydrogenase and pyruvate kinase of the glycolytic pathway, and glucose 6-phosphate dehydrogenase of the Entner-Doudoroff pathway were studied, f
Genetics and Molecular Biology. Publicado em: 2003
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10. Estudo da secreção de insulina em pacientes com deficiencia de glicose-6-fosfatodesidrogenose
Glucose - 6 - Phosphate Dehydrogenase Deficiency (G - 6 - PD) is an inborn error of carbohydrate metabolism in which the ativity and/or stability of G- 6 - PD (enzyme that catalyses the initial reation of the pentose phosphate pathway) is decresead. Recognition that deficiency of G - 6 - PD also occurs in other cells tissues and biologic fluids of affected p
Publicado em: 1990
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11. Mutants of the Pentose Phosphate Pathway in Aspergillus nidulans
Mutants of the pentose phosphate pathway have been isolated in Aspergillus nidulans. These fail to grow on a variety of carbohydrates that are catabolized through the pentose phosphate pathway. They also grow poorly on nitrate and nitrite as sole nitrogen sources. The pentose phosphate pathway mutations have been assigned to two unlinked genes. Mutants with
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12. Nonoxidative Pentose Phosphate Pathway in Veillonella alcalescens
Crude cell-free extracts of Veillonella alcalescens C1, an anaerobe unable to ferment glucose, were assayed for individual enzymes of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase activities were not detectable. Constituent enzymes of the nonoxidative limb of the pentose phosphate pathway were demonstra