Permeation Kinetic
Mostrando 1-12 de 42 artigos, teses e dissertações.
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1. Influence of different formulation variables on the performance of transdermal drug delivery system containing tizanidine hydrochloride: in vitro and ex vivo evaluations
The present study was aimed at preparation of transdermal patches of tizanidine HCl, evaluation of the effect of polymers on in vitro release pattern of the drug, and the effect of permeation enhancers on the penetration of the drug through the rabbit skin. Various proportions of hydrophilic (HPMC) and hydrophobic (Eudragit L-100) polymers were used with PEG
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
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2. Efficiency of Single Site Phase Transfer Catalyst in Free Radical Polymerization of Butyl Methacrylate - A Kinetic Study
ABSTRACT The effectiveness of single site phase transfer catalyst- 2- benzoylethyldecyldimethylammonium bromide has been studied with the help of kinetics of free radical polymerization of butyl methacrylate. The radical polymerization was catalysed with single site phase transfer catalyst, initiated by water soluble potassium peroxydisulphate initiator in e
Braz. arch. biol. technol.. Publicado em: 23/01/2017
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3. Estudo da captura de dióxido de carbono por misturas de hidróxido de cálcio e óxido de magnésio em baixas temperaturas
The present work has studied the carbonation reaction of hydrated lime modified by small percentages of magnesium dioxide (MgO) by the carbon dioxide (CO2) from the exhaust gas of a petrol engine. For this purpose, spherical pellets of solid adsorbents were synthesized and submitted to carbonation essays in a lab-scale fixed bed reactor. The samples conversi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/02/2012
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4. Investigação da polimerização via radical livre usando iniciadores trifuncionais / Investigation of free radical polymerization using trifunctional initiators
Researchers from industries and universities have investigated the use of initiators with functionality greater than one, in free radical polymerization. These types of initiators are able to increase the polymerization reaction rate with no decrease in molecular weight. Besides, initiators with functionality greater than two (multifunctional initiators), th
Publicado em: 2009
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5. Desenvolvimento, caracterizaÃÃo e estudo de permeaÃÃo cutÃnea de diclofenaco de dietilamÃnio em sistemas tÃpicos nanoemulsionados
The nanoemulsions (NE) are transparent, isotropic and thermodynamically stable systems, formed spontaneously under a specific set of experimental conditions from mixtures of water and oil phases stabilized by a surfactant or a mixture of surfactant and cosufactant. Because of their properties, especially the ability to carry lipophilic and hydrophilic drugs
Publicado em: 2008
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6. Estudo da copolimerização em mini emulsão de metacrilato de metila/metacrilato de etila / Study of methyl methacrylate/ethyl methacrylate in mini emulsion copolimerization
Reduction of volatile organic compounds (VOC) usage is a constant environmental demand. Polymeric aqueous emulsion of low surfactant contends produced from direct miniemulsion synthesis are used with advantages to replace organic solvents media as well as aqueous emulsions of high surfactant concentration. Water as continuous phase and organic monomers with
Publicado em: 2008
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7. Polymeric coating and pharmacokinetic of chitosan granules containing ddI incorporated in microparticles / Revestimento polimerico e farmacocinetica de granulos gastrorresistentes contendo didanosina incorporada em microparticulas de quitosana
This work studied the production and pharmacokinetic of a new pharmaceutical formulation of the didanosine (ddI) drug ,composed by chitosan granules containing ddI incorporated in microparticles, for oral administration in the AIDS therapy. The advantages of this new pharmaceutical formulation compared to the conventional one are: to assure ddI stability in
Publicado em: 2008
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8. CinÃtica de difusÃo in vitro e atividade in vivo de preparaÃÃes magistrais de cetoprofeno
The Ketoprofen is a nonsteroidal antiinflammatory drug (NSAID) used in the symptomatic treatment for rheumatoid arthritis. The oral administration, for a long period can cause gastric disorders, as stomach upset, pains and ulceration. The emulgel studied in this work was based on PLO (Pluronic Lecithin Organogel) and was developed with the aim of reaching
Publicado em: 2007
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9. Rheology and transition shapes of elastic liposomes in nanopores membranes / Reologia e transição de formas de lipossomas elasticos em membranas de nanoporos
In this work, liposomes prepared with comercial egg lecithin and octaoxyethylenelaurate-ester (PEG-8L) were characterized and studied in respect to PEG-8L incorporation, shape transitions, elasticity and rheology in nanopores membranes. Conventional liposomes (without PEG-8L) were used as control. The concentrated caffeine, extracted of guarana seeds, was in
Publicado em: 2007
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10. Synthesis and characterization of poly-o-toluidine: kinetic and structural aspects
Poly(o-methylaniline) (poly-o-toluidine, PTOL) was synthesized by chemical oxidation of o-toluidine with ammonium peroxydisulfate in an aqueous 1.0 mol L-1 HCl solution. The progress of polymerization was followed by measuring the open-circuit potential (OCP) of a Pt electrode immersed in the reaction medium with the polymerization time. The chemical synthes
Materials Research. Publicado em: 2005-03
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11. Desenvolvimento e avaliação farmacologica de formulações de liberação controlada com anestesicos locais amino-amidas ciclicos : bupivacaina, mepivacaina e ropivacaina / Development and pharmacological evaluation of drug-delivery systems for cyclic amino-amide local anesthetics: bupivacaine, mepivacaine and ropivacaine
Local anesthetics (LA) are among the different classes of pharmacological compounds used to attenuate or to eliminate pain. These drugs, which are able to reversibly block the excitation/transmission of the nerve impulse in axons have a relatively short action and a significant toxicity to the Central Nervous and Cardiovascular systems. In order to prolong t
Publicado em: 2005
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12. Produção, recuperação e caracterização de proteinas alergenicas da biomassa de Drechslera (Helminthosporium) monoceras obtida por fermentação em estado solido
The purpose of this work was the production, recovery and characterization of allergenic proteins of Drechslera (Helminthosporium) monoceras biomass; cultivated by solid-state fermentation, for the obtainment of standardized mould allergenic extract, applicable to diagnosis of allergy diseases. Bioreactors based on Raimbault-type aerated fixed bed columns we
Publicado em: 2002