Phospholipid Bilayer
Mostrando 1-12 de 264 artigos, teses e dissertações.
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1. Liposome and Their Applications in Cancer Therapy
ABSTRACT Liposomes, the vesicles of phospholipid bilayer, can encapsulate both hydrophilic and lipophilic drugs and protect them from degradation. Liposomes have been extensively studied and continue to create intense interest in research since their discovery in the mid-1960s. Since then, liposomes have been considered to be the most successful nanocarriers
Braz. arch. biol. technol.. Publicado em: 08/03/2016
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2. Lepromatous leprosy patients produce antibodies that recognise non-bilayer lipid arrangements containing mycolic acids
Non-bilayer phospholipid arrangements are three-dimensional structures that form when anionic phospholipids with an intermediate structure of the tubular hexagonal phase II are present in a bilayer of lipids. Antibodies that recognise these arrangements have been described in patients with antiphospholipid syndrome and/or systemic lupus erythematosus and in
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-12
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3. Dispersões lipídicas de dimiristoil fosfatidilglicerol: um estudo termo-estrutural / Lipid dispersions of dymiristoyl phosphatidylglycerol: a thermo-structural study
Dispersions of the saturated anionic phospholipid dimyristoyl phosphatidyl glycerol (DMPG) have been extensively studied regarding their peculiar thermo-structural behavior. At low ionic strength, the gel-fluid transition is spread along nearly 17 ºC, displaying several thermal events in the calorimetric profile, quite different from the single sharp peak a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/12/2010
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4. Structural properties of lipid reconstructs and lipid composition of normotensive and hypertensive rat vascular smooth muscle cell membranes
Multiple cell membrane alterations have been reported to be the cause of various forms of hypertension. The present study focuses on the lipid portion of the membranes, characterizing the microviscosity of membranes reconstituted with lipids extracted from the aorta and mesenteric arteries of spontaneously hypertensive (SHR) and normotensive control rat stra
Brazilian Journal of Medical and Biological Research. Publicado em: 31/07/2009
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5. Molecular dynamics of articaine in POPC membranes / Dinamica molecular de articaina em membranas POPC
We studied the interactions of articaine - a local anesthetic widely used for me- dical and odontological applications - with model membranes of POPC (palmitoyl-oleyl-phosphatidylcholine) at biological relevant conditions. We have employed molecular dynamics technique, which allowed us to investigate the system at molecular level. Firstly, we applied quantum
Publicado em: 2009
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6. Development of membrane biosensors and characterization of the interactions between cytochrome c and hybrid bilayer membranes by Surface Plasmon Resonance / Desenvolvimento de biosensores de membranas e caracterização da interação entre citocromo c e bicamadas híbridas por ressonância plasmônica de superfície
The aim of this work was to develop membrane biosensors based on Surface Plasmon Resonance (SPR) and to apply them to study the interactions between cytochrome c (cyt c) and model membranes. SPR is an optical technique that provides high-sensitivity measurements of refractive index (n), allowing the characterization of the adsorption and desorption of molecu
Publicado em: 2008
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7. Avaliação da biocompatibilidade de magnetolipossomas à base de nanopartículas de maghemita
Nanobiotechnology represents an emerging and promising research field. Nanostructured materials, such as magnetic fluids and magnetoliposomes (MLs), have been proposed for drug-delivery systems and thermal-based cancer therapy amongst other several applications in biomedicine. In particular, MLs are physiologically stable structures, consisting of magnetic n
Publicado em: 2008
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8. Estudo de monocamadas fosfolipidicas nanoestruturadas obtidas por LB para aplicações em biossensores
There has been long-standing interest in the physical chemical properties of defined mixtures of cholesterol and phospholipids in monolayer and bilayer membranes. They also provide insight into certain properties of the membranes of animal cells. Even if phospholipids and sphingolipids build up the matrix of cellular membranes, sterols are essential componen
Publicado em: 2007
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9. Effect of metallic pollutants in marine algae pigments contents and evaluation of carotenes structural features in mimetic membranes / Efeito de poluentes metálicos nos níveis de pigmentos fotossintéticos presentes em algas marinhas e avaliação do papel estrutural de carotenos em membranas miméticas
This work involves the study of the levels of photosynthetic pigments, carotenoids and chlorophylls, contained in the marine algae Tetraselmis gracilis and Gracilaria tenuistipitata, under conditions of cellular senescence and anthropogenic stress (metallic pollution). Due to the fundamental organizational role of carotenoids in thylakoid membranes, its stru
Publicado em: 2007
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10. Estratégias para prospecção e predição de peptídeos bioativos
Chapters one and two deal with the isolation and identification of bioactive peptides from the skin secretion of Phyllomedusa hypochondrialis. The first chapter demonstrates the use of protemic techniques, mainly mass spectrometry, for the study of bradykinin related peptides (BRPs) present in the amphibians secretion and freshly dissected skin fragments. Ei
Publicado em: 2007
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11. Optimum adsorption of phospholipid bilayer on silica and reconstitution of receptor function. / Adsorção ótima de bicamada fosfolipídica sobre sílica e reconstituição do reconhecimento receptor-ligante
The general objective of this project was to continue evaluating the suitability of amphiphiles that aggregate in aqueous solution forming bilayers, to cover surfaces of silica. A secondary objective pursued was to promote the reconstitution of the receptor-ligand function, having as a model the monosialoganglioside GM1 and the enterotoxin of the choleric vi
Publicado em: 2006
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12. Preparação e caracterização de lipossomas elasticos e elastico-magneticos para administração transdermica de moleculas bioativas / Preparation and characterization of elastic and elastic-magnetic liposomes for transdermal transport of drugs
The purpose of this work was to study the preparation and characterization of elastic and elastic-magnetic liposomes designed to facilitate the transdermal transport of drugs. The prepared liposomes were unilamellar, composed by synthetic dymirystoylphosphatidylcholine (DMPC), hydrogenated soy phosphatidylcholine or egg phosphatidylcholine (PCegg) as structu
Publicado em: 2005