Photodynamic Process
Mostrando 1-12 de 26 artigos, teses e dissertações.
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1. Synthesis, Characterization, Spectroelectrochemical, Photophysical and HSA-Binding Properties of Novel and Versatile meso-Tetra(4-pyridylvinylphenyl)porphyrins Coordinated to Ruthenium(II)-Polypyridyl Derivatives
The free-base meso-tetra(4-pyridylvinylphenyl)porphyrin (1a) and its zinc(II) complex were synthesized and then functionalized with [Ru(bpy)2Cl]+ units (2a and 2b) via conventional methods and evaluated in terms of photophysical, electrochemical and biological aspects. All porphyrins present moderate singlet oxygen production and fluorescence quantum yield,
J. Braz. Chem. Soc.. Publicado em: 2020-11
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2. EXPERIMENTAL STUDY OF THE NEUROTOXIC EFFECTS OF PHOTODYNAMIC THERAPY ON THE SPINAL CORD
RESUMO Objetivo Avaliar os efeitos da terapia fotodinâmica (PDT) na dura-máter usando os fotossensibilizadores cloreto de alumínio ftalocianina e azul de metileno em ensaios in vivo. Métodos Cinquenta e seis ratos Wistar machos divididos em dois grupos; um submetido à PDT e o outro submetido aos fotossensibilizadores sem a fotoativação (controle). O
Coluna/Columna. Publicado em: 02/09/2019
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3. Exploring Light-Based Technology for Wound Healing and Appliance Disinfection
Our goal was to build, characterize and test a red light-emitting diode (LED) device suitable for wound healing and disinfection of biomedical appliances. We designed and built a unique irradiator metallic box, for which irradiation distribution and spectral irradiance were calculated. In addition, we explored the device’s potential in photobiology compari
J. Braz. Chem. Soc.. Publicado em: 2015-12
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4. Investigação do efeito de grupos periféricos de rutênio sobre as propriedades fotofísicas de porfirinas
In the last few years the search for new organometallic complexes that exhibit large and fast optical responses at UV-Vis and near IR spectrum regions have attracted a considerable interest because of their potential application in devices such as sensors, optical limiters, switches and in medicine, being used as sensitive drugs in photodynamic treatments. A
Publicado em: 2011
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5. AÃÃo da terapia fotodinÃmica antimicrobiana sobre biofilmes orais crescidos in vitro e in situ / The Photodynamic Antimicrobial Chemotherapy effect on in vitro and in situ biofilms
The treatment of diseases caused by oral biofilms involves mechanical removal and use of antibiotics and antiseptics which can lead to problems of bacterial resistance. Photodynamic antimicrobial chemotherapy (PACT) represents an alternative option to conventional treatment, promoting bacterial killing by photo-sensitization of microbial components. This stu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/03/2010
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6. Influência de diferentes sistemas de solvente água-etanol sobre as propriedades físico-químicas e espectroscópicas dos compostos macrocíclicos feofitina e clorofila α
This work focus on the influence of solvent on the photophysical properties of chlorophyll α and pheophytin. Both compounds are related to the photosynthesis process and are considered prototypes of photosensitizers in Photodynamic Therapy. Fluorescence measurements were developed using water/ethanol mixtures at different compositions, since both solvents c
Química Nova. Publicado em: 2010
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7. Avaliação do uso do laser e processos fotodinâmicos na estimulação e crescimento celular de osteoblastos. Avaliação fotofísica e fotobiológica na presença e ausência de fármacos fotossensíveis / Evaluation of the use of laser and photodynamic processes in cell growth and stimulation of osteoblasts. Evaluation photophysical and photobiology in the presence and absence of drugs designed
The laser is a source of non ionizing radiation highly concentrated and coherent that in contact with different tissues induce thermal, photochemical and non-linear effects according to the type of the laser. Currently, the laser has been used routinely in many areas of science, as well as in medicine and dentistry. The treatments using laser radiation of lo
Publicado em: 2009
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8. Processos fotodinâmicos para bioestimulação tecidual em modelo in vitro de pele humana empregando-se laser de baixa potência e cloro alumínio ftalocianina em nanoemulsão / Photodynamic Process for tissue photostimulation in skin human in vitro model using low potency laser and chloro aluminum phthalocyanine into nanoemulsion
Este trabalho de tese de doutorado baseia-se em um desenvolvimento científico amplamente multidisciplinar combinando-se protocolos, técnicas e ensaios experimentais da área de tecnologia farmacêutica, nanotecnologia, engenharia tecidual e fotobiologia. O trabalho foi realizado em duas etapas subsequentes. Primeiramente realizaram-se os estudos de desenvo
Publicado em: 2009
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9. Evaluation of riboflavin citotoxicity and phototoxicity : determination of molecular markers in inflammation, senescence and cell death / Avaliação da citotoxicidade e fototoxicidade da riboflavina : determinação de marcadores moleculares de inflamação, senescencia e morte celular
Riboflavin (RF) is a water soluble vitamin which belongs to vitamin B2 complex, an essential precursor of FMN and FAD coenzymes. Besides being a component of coenzymes, RF displays antitumoral and photossensitizing activities. The main proposal of this study was to evaluate the RF phototoxicity, as well as to determine molecular markers of inflammation, sene
Publicado em: 2009
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10. Morphometric, molecular and radiographic analysis of the alveolar repair process after antimicrobial photodynamic therapy in Wistar rats / Análise morfométrica, radiográfica e molecular do processo de reparo alveolar após a terapia fotodinâmica antimicrobiana em ratos Wistar
Introdução: Com o aumento da resistência bacteriana à antibioticoterapia tornou-se necessário o desenvolvimento de técnicas antimicrobianas alternativas. Assim, na busca de novas metodologias contra microrganismos, estudos usando a Terapia Fotodinâmica (TFD) antimicrobiana tem sido realizados. Objetivo: Realizar análise morfométrica, radiográfica e
Publicado em: 2009
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11. STUDY OF THE AGGREGATION AND PHOTOBLEACHING DYNAMIC OF METHYLENE BLUE AND ORTO-TOLUIDINE BLUE AS REGARDS THEIR PHOTODYNAMIC EFFECTIVENESS / Estudo da dinâmica de fotodegradação e agregação das fenotiazinas azul de metileno e azul orto-toluidina com relação à eficiência fotodinâmica
Photodynamic therapy may be a viable alternative to treat localized infections, although to obtain a resourceful clinical application, parameters linked with photodynamic efficiency must be analyzed in order to achieve quantifiable results. The aims of this study were to investigate the aggregation dynamic of the photosensitizers methylene blue and orto-tolu
Publicado em: 2007
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12. Development of photosensitizing nanoparticles / Desenvolvimento de nanopartículas fotossensibilizadoras
In this work we present the synthesis and the characterization (structural, photophysical, photochemical and photobiological) of nanoparticles with incorporated photosensitizers (PS) Methylene Blue (MB) and Thionin. MB and Thionin were incorporated in sil-MB and sil-Th nanoparticles through sol-gel process. In the case of Cab-Th nanoparticles Thionin was lin
Publicado em: 2007