Phytopharmaceutical
Mostrando 1-12 de 15 artigos, teses e dissertações.
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1. Nectandra falcifolia: potential phytopharmaceutical for skin damage protection designed by statistical approach and characterized by photoacoustic spectroscopy
AbstractPhytopharmaceutical products are being used in the treatment and prevention of health problems. Nowadays, the development and evaluation of novel pharmaceutical products is expensive and time consuming. A statistical approach is a good tool for optimal development processes. Nectandra falcifolia (Nees) J.A. Castigl. ex Mart. Crov. & Piccinini, Laurac
Rev. bras. farmacogn.. Publicado em: 2015-06
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2. Characterization of intestinal absorption of C-glycoside flavonoid vicenin-2 from Lychnophora ericoides leafs in rats by nonlinear mixed effects modeling
AbstractVicenin-2 (apigenin-6,8-di-C-β-d-glucopyranoside) is present in hydroalcoholic extracts of the Brazilian species Lychnophora ericoides Mart., Asteraceae, leaves, and the biological effects of this compound have been demonstrated including anti-inflammatory, antioxidant and anti-tumor effects in rat models. Given the potential of this compound as a p
Rev. bras. farmacogn.. Publicado em: 2015-06
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3. Genotoxic Maillard byproducts in current phytopharmaceutical preparations of Echinodorus grandiflorus
Extratos de Echinodorus grandiflorus, obtidos a partir de folhas secas por três técnicas diferentes, foram avaliados pelo ensaio de indução lisogênica bacteriana (Induteste), em relação às propriedades genotóxicas. As amostras foram previamente esterilizadas por vapor de água (autoclavação) ou luz ultravioleta. Somente os extratos preparados por
An. Acad. Bras. Ciênc.. Publicado em: 04/08/2014
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4. Evaluation of reversible contraceptive potential of Cordia dichotoma leaves extract
Considering the safety-risk ratio of steroidal contraceptives, the present work was carried out to evaluate ethno-contraceptive use of Cordia dichotoma G. Forst., Boraginaceae, leaves (LCD). Preliminary pharmacological screening was performed on post-coital female albino rats. The leaves extract (LD50 5.50 g/kg bw) showed 100% anti-implantation activity (n=1
Rev. bras. farmacogn.. Publicado em: 05/03/2013
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5. Special issue on phytopharmaceutical technology
Rev. bras. farmacogn.. Publicado em: 2013-02
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6. Desenvolvimento e caracterização de microemulsão à base de óleo de sucupira (P. emarginatus Vog. Fabaceae) e avaliação da atividade antiinflamatória tópica / Development and characterization of oil sucupira microemulsion (P. emarginatus Vog. Fabaceae) and evaluation of topical anti-inflammatory activity
Pterodon emarginatus Vogel, conhecida popularmente como sucupira branca, é uma espécie arbórea nativa do cerrado brasileiro encontrada nos estados de Goiás, Minas Gerais, São Paulo e Mato Grosso do Sul. Vários estudos comprovam suas atividades terapêuticas como antiinflamatório, antinociceptivo, analgésica, antimicrobiana, entre outros. O objetivo d
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/02/2012
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7. Desenvolvimento e caracterização de microemulsão à base de óleo de sucupira (P. emarginatus Vog. Fabaceae) e avaliação da atividade antiinflamatória tópica / Development and characterization of oil sucupira microemulsion (P. emarginatus Vog. Fabaceae) and evaluation of topical anti-inflammatory activity
Pterodon emarginatus, popularly known as Sucupira Branca is a native species found in the Brazilian Savannahs in states of Goiás, Minas Gerais, São Paulo, Mato Grosso do Sul. Several studies have confirmed their therapeutic activities as antiinflammatory, antinociceptive, analgesic, antimicrobial, among others. The aim of this study was to develop a microe
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/02/2012
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8. Technological development of Cecropia glaziovi extract pellets by extrusion-spheronization
Cecropia glaziovi Snethl., Urticaceae, is commonly used in South America and is one of the species included in the Brazilian Medicinal Plants Research Program. Pharmacological studies have led to reports of the potential of C. glaziovi as a hypotensive, antiasthmatic and anxiolytic agent. The strict requirements regarding the quality, safety and effectivenes
Rev. bras. farmacogn.. Publicado em: 11/10/2012
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9. Optimization of the extraction of curcumin from Curcuma longa rhizomes
The aim of this work was to study the effect of dynamic maceration factors upon the curcumin content of Curcuma longa L., Zingiberaceae, extracts and to determine the optimum set of parameters for the extraction of curcumin using a 2(5) full factorial design and the response surface methodology. Under the established conditions, the content of soluble solids
Rev. bras. farmacogn.. Publicado em: 09/10/2012
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10. Spray drying of Eugenia dysenterica extract: effects of in-process parameters on product quality
A 2³ full factorial design was used to assess the impact of spraying air flow rate (30-50 L/min), drying air inlet temperature (90-150 ºC) and extract feed rate (4-6 g/min) on the quality of Eugenia dysenterica DC., Myrtaceae, spray-dried extracts. Response surface methodology (RSM) was applied to analyze the significance of the effects of process factors
Rev. bras. farmacogn.. Publicado em: 18/09/2012
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11. Bioactive compounds in Bidens pilosa L. populations: a key step in the standardization of phytopharmaceutical preparations
The total flavonoid content (TFC), total polyphenols content (TPC), and in vitro antioxidant activity (AA) of six Bidens pilosa L., Asteraceae, populations harvested from different localities were evaluated in this work. The plants were separated in roots, stems, and leaves/flowers, and the influence of extraction methods was investigated.Areversed-phase hig
Rev. bras. farmacogn.. Publicado em: 23/08/2012
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12. Isolation and quantitative HPLC-PDA analysis of lupeol in phytopharmaceutical intermediate products from Vernonanthura ferruginea (Less.) H. Rob.
Prior to obtain a standardized dried extract from V. ferruginea, lupeol was first time isolated from leaves and used as chemical maker. An analytical method using HPLC-PDA for lupeol determination in V. ferruginea intermediate products was developed using a C8 reverse-phase column, acetonitrile-acetic acid (99.99:0.01, v/v) as mobile phase at 0.8 mL min-1, o
Química Nova. Publicado em: 2012