Pinealocytes
Mostrando 1-12 de 13 artigos, teses e dissertações.
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1. Characterization of Lypopolyssacharide (LPS) effect on rat pinealocytes / Caracterização dos efeitos de LPS em pinealócitos de rato em cultura
Accumulating evidences put the pineal gland and the immune system reciprocally linked by bidirectional communication. Rat pineal gland constitutively activated NFkB, which plays a role on melatonin synthesis, is a preferential transduction pathway for cytokines and glucocorticoids (Ferreira et al., 2005; Fernandes et al., 2006). TNFα transiently inhibit
Publicado em: 2009
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2. Papel da interação parácrina entre astrócitos e pinealócitos na mediação do efeito potenciador da angiotensina II sobre a síntese de melatonina induzida pela estimulação noradrenérgica na glândula pineal de ratos. / Paracrine interaction between glial cells and pinealocytes determines the potentiating effects of angiotensin II on noradrenaline-stimulated melatonin synthesis on the rat pineal gland.
We have previously demonstrated that Angiotensin II (Ang II) potentiates the noradrenaline-stimulated (Nor+) melatonin synthesis in the rat pineal gland [Baltatu et al.,J. Neurochem.(2002)80, 328-334]. The aim of the present paper was to study the possible paracrine interactions between glial cells and pinealocytes in the rat pineal gland. To accomplish this
Publicado em: 2008
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3. Glutamate modulation of melatonin synthesis in the rat pineal gland. / Síntese de melatonina na glândula pineal de ratos: modulação pelo glutamato.
The aim of this work was to study the effects of glutamate on melatonin synthesis, investigating the glutamate receptors involved and a possible interaction between the two predominant cell types of the pineal gland, pinealocytes and astrocytes; moreover, it was investigated the involvement of the transcription factor NF-kB on the glutama
Publicado em: 2008
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4. Anatomia macroscópica e microscópica da glândula pineal do macaco Cebus apella / Macroscopy and microscopic anatomy of the pineal gland of the monkey (Cebus apella)
The objective of this study is to describe the anatomical organization of the pineal gland of the Cebus apella monkey, analyzing its macrocospic and microscopical aspects, seen under the optics of the light microscopy, electronic microscopy of transmission and microanalysis by emission of X-Ray. In the development of this study 12 units of Cebus apella monke
Publicado em: 2006
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5. Stimulation of a nicotinic ACh receptor causes depolarization and activation of L-type Ca2+ channels in rat pinealocytes.
1. Membrane voltage (Vm) recordings were obtained from isolated rat pinealocytes using the patch-clamp technique. In parallel to the electrophysiological experiments, intracellular Ca2+ measurements were performed using fura-2. 2. The resting Vm averaged -43 mV and replacement of extracellular NaCl by KCl completely depolarized the cells. This indicates that
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6. Ultrastructure of the pineal gland in the adult rat.
The ultrastructure of the rat pineal gland was studied from 75 days until 10 months of age. Type I pinealocytes of young adults showed nuclei with dispersed chromatin, numerous infoldings of the nuclear envelope and well developed nucleoli. The cytoplasm displayed many mitochondria and clusters of smooth endoplasmic reticulum. With increasing age, there was
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7. Postnatal development of cell types in the rat pineal gland.
The morphological development of the rat pineal gland has been studied from 1 to 60 days of age. During the first days, undifferentiated cells (pinealoblasts) with scanty cytoplasm and frequent mitotic figures were observed. The differentiation of cell types (Types I and II pinealocytes) began on the third day after birth and was completed by days 15-20. At
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8. Demonstration of circadian rhythm in granular vesicle number in pinealocytes of mice and the effect of light: semi-quantitative electron microscopic study.
Adult (70-100 days) male dd-mice were killed at 7 a.m., 1 p.m., 7 p.m. and 1 a.m. under controlled daily photoperiods (L: 7 a.m.-7 p.m.) and temperature, and at 6, 12 and 18 hours after exposure to continuous lighting which started at 7 p.m. Montage photographs were made from electron micrographs at x8200 based on mesh hole areas, using either 150 or 300 mes
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9. Postnatal evolution of the rat pineal gland: light microscopy.
The postnatal development and morphology of the adult albino rat pineal gland was studied from one day up to ten months of age. During postnatal life there was a marked increase in gland and pinealocyte volume, more intense during the first 45 days. After ten days, the differences in nuclear morphology of parenchymal cells showed two different types of pinea
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10. Concurrent uveoretinitis and pineocytoma in a child suggests a causal relationship.
Uveoretinitis was observed in a 9-year-old girl 6 months prior to the clinical appearance of a pineal tumour. Surgical removal was not successful but biopsy revealed a parenchymal neoplasm with differentiated pinealocytes and absent mitotic activity. Some of the tumour cells contained S-antigen, rhodopsin, and serotonin. Systemic glucocorticoid therapy follo
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11. Morphological findings relating to the problem of cortex and medulla in the pineal glands of rat and hamster.
Because, in previous investigations on the rat pineal gland, karyometric studies of pinealocytes from cortical and medullary regions had yielded contradictory results, experiments were carried out to resolve this problem. In immersion-fixed, paraffin-embedded pineal glands, nuclear size of cortical regions was invariably larger than that in the medulla, the
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12. Antagonistic actions of analogs related to growth hormone-releasing hormone (GHRH) on receptors for GHRH and vasoactive intestinal peptide on rat pituitary and pineal cells in vitro
Peptide analogs of growth hormone-releasing hormone (GHRH) can potentially interact with vasoactive intestinal peptide (VIP) receptors (VPAC1-R and VPAC2-R) because of the structural similarities of these two hormones and their receptors. We synthesized four new analogs related to GHRH (JV-1–50, JV-1–51, JV-1–52, and JV-1–53) with decreased GHRH anta
The National Academy of Sciences.