Pituitary Factor 1
Mostrando 1-12 de 189 artigos, teses e dissertações.
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1. Corticotropin-releasing factor receptor signaling and modulation: implications for stress response and resilience
Abstract Introduction In addition to their role in regulation of the hypothalamic-pituitary-adrenal-axis, corticotropin-releasing factor (CRF) and its related peptides, the urocortins, are important mediators of physiological and pathophysiological processes of the central nervous, cardiovascular, gastrointestinal, immune, endocrine, reproductive, and skin
Trends Psychiatry Psychother.. Publicado em: 2020-06
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2. Is biochemical hypoglycemia necessary during an insulin tolerance test?
ABSTRACT Objective The insulin tolerance test (ITT) has been accepted as the gold standard test for assessing the integrity of the growth hormone (GH) – insulin-like growth factor (IGF-1) axis and the hypothalamic-pituitary-adrenal (HPA) axis. The goal of the test is to achieve clinical and biochemical hypoglycemia at a blood glucose level ≤ 40 mg/dL t
Arch. Endocrinol. Metab.. Publicado em: 2020-02
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3. Effects of Dietary Energy Concentration on Reproductive Hormone Secretion and Gene Expression in the Hypothalamus-Pituitary-Gonad Axis in Laying Geese
ABSTRACT The objective of the study was to investigate the mechanism by which dietary energy concentration regulates laying performance in geese. Eighty 558-day-old female Sichuan White geese were randomly allotted to two dietary treatments, each treatment was fed 1 of 2 experimental diets containing 10.00 (deficient) or 11.80MJ/kg metabolizable energy (suff
Braz. J. Poult. Sci.. Publicado em: 11/11/2019
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4. Polymorphisms of leptin, β-lactoglobulin and pituitary transcription factor have no effect on milk characteristics in crossbred cows
RESUMO O objetivo deste trabalho foi identificar polimorfismos genéticos de leptina, β-lactoglobulina e fator de transcrição pituitária (PIT1) e avaliar seus efeitos na composição química e na contagem de células somáticas de leite de vacas leiteiras mestiças que vivem em um clima quente. Um total de 291 vacas leiteiras mestiças foram investigada
Arq. Bras. Med. Vet. Zootec.. Publicado em: 06/06/2019
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5. Elevated IGF-1 with GH suppression after an oral glucose overload: incipient acromegaly or false-positive IGF-1?
ABSTRACT Objective To report the evolution of patients with a suggestive clinical scenario and elevated serum insulin-like growth factor-1 (IGF-1), but growth hormone (GH) suppression in the oral glucose tolerance test (OGTT), in whom acromegaly was not initially excluded. Subjects and methods Forty six patients with a suggestive clinical scenario, who h
Arch. Endocrinol. Metab.. Publicado em: 25/08/2016
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6. Pituitary deficiency after aneurysmal subarachnoid hemorrhage
OBJECTIVE: Aneurysmal subarachnoid hemorrhage puts patients at high risk for the development of pituitary insufficiency. We evaluated the incidence of pituitary dysfunction in these patients and its correlation with clinical outcome. METHODS: Pituitary function was tested in 66 consecutive patients in the first 15 days after aneurysmal subarachnoid hemorr
Clinics. Publicado em: 2013-06
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7. Fibromyalgia and the relevance of the whole-body vibration exercises in vibratory platforms: a short review
Among nonpharmacological strategy to manage fibromyalgia, exercise (aerobic) has shown efficacy. Whole-body vibration (WBV) exercise has been proposed as a potential clinical intervention. WBV would induce increase in growth hormone (GH). An impairment of the hypothalamic-pituitary-GH-Insulin Growth Factor-1(IGF-1) axis has been implicated in the pathophysio
Brazilian Archives of Biology and Technology. Publicado em: 2012-02
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8. Association of pit1 genotypes with growth traits in canchim cattle.
Use of genetic markers can aid on the identification of animals with highest breeding values in beef cattle. The PIT1 gene codes for the Pit-1 transcription factor is essential for the activation of prolactin, growth hormone and PIT1 genes. This research is an investigation of the effect of PIT1- HinfI polymorphism on growth traits of 509 Canchim animals, fr
Scientia Agrícola. Publicado em: 2011
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9. Papel da via lkaros-FGFR4 na evolução pós-cirúrgica dos pacientes com doença de Cushing / Ikaros-FGFR4 pathway: role in the postoperative outcome of Cushings disease
Introduction: The mechanisms involved in the molecular pathogenesis of corticotroph pituitary tumors are complex, heterogeneous and in most cases remain unknown. Changes in the expression of components of Ikaros (Ik) pathway, such as receptor 4 of fibroblast growth factor (FGFR4), have been detected in pituitary tumors including corticotropinomas. Imbalance
Publicado em: 2010
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10. Estudos dos genes Tbx19 e Crhr1 em cães da raça poodle com hipercortisolismo ACTH-dependente / Study of Tbx19 and Crhr1 genes in Poodle dogs with ACTH-dependent hypercortisolism
The ACTH-dependent hypercortisolism (ADH), also called Cushings disease, is one of the most commonly diagnosed endocrine diseases in dogs. The symptoms occur due to glucocorticoids excess leading to gluconeogenic, catabolic, anti-inflammatory and immunosuppressive effects in multiple organs and systems. There is a high incidence of Cushings disease in Poodle
Publicado em: 2010
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11. EXPRESSÃO DAS MAPKs EM FOLÍCULOS OVARIANOS E CORPOS LUTEOS EM DIFERENTES FASES DO CICLO ESTRAL DE BOVINOS / EXPRESSION OF MAPKs IN ovarian follicles is Lutea at different stages of estrous cycle CATTLE
Bovine estrous cycle activates the pathways of MAPKs (mitogen activated protein) via oscillation of hypothalamus-pituitary-gonad axis hormones. The objective of this work was to evaluate in vivo the frequency of expression of active (phosphorylated) form, of p-MEK 1/2 and p-ERK1/2 in all types of ovarian follicles and corpora lutea in different phases of the
Publicado em: 2009
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12. Expression of p53 protein in pituitary adenomas
Inactivating mutations of TP53, a tumor suppressor gene, are associated with abnormal cell proliferation. Although p53 expression is common in many human malignancies, p53 protein has seldom been evaluated in pituitary tumors. When detected, the percentage of p53-positive cells is low, and, in general, it is exclusive for invasive lesions. The aim of the pre
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-05