Poli A Binding Protein
Mostrando 1-10 de 10 artigos, teses e dissertações.
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1. Estudos com a poli-A binding protein 1 de Trypanosoma brucei sugerem nova função nos eventos de splicing e exportação nuclear / Studies with Trypanosoma brucei poly(A)-binding protein 1 suggest a novel function in splicing and nuclear export events
Protozoa of the genus Trypanosoma infect millions of people every year and collectively contribute to the human misery by causing several neglected tropical diseases. Several intriguing molecular pathways are found in these parasites also, rendering them particularly attractive for biochemical investigation. This unique eukaryotic cells lack mechanisms to co
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/12/2011
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2. Guided tissue regeneration: in vitro biocompatibility of the membrane of poly(vinylidene-trifluoroethylene)/barium titanate composite / Regeneração tecidual guiada: estudo da biocompatibilidade in vitro da membrana do compósito de poli(vinilideno-trifluoretileno)/titanato de bário
O princípio da regeneração tecidual guiada (RTG) baseia-se na utilização de membranas biocompatíveis com a finalidade de impedir a migração dos tecidos conjuntivo e epitelial para a ferida, permitindo que células do ligamento periodontal repovoem a superfície radicular e regenerem o aparato de inserção do dente. A RTG tem sido utilizada em divers
Publicado em: 2009
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3. The release element of the yeast polymerase I transcription terminator can function independently of Reb1p.
The Saccharomyces cerevisiae polymerase I (polI) transcription terminator utilizes a DNA-binding protein (Reb1p) as part of a signal that causes the polymerase to pause prior to release from the template. To study the release element of the terminator, independent of the Reb1p pause signal, we have replaced the Reb1p binding site with the binding site for th
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4. CK2 Forms a Stable Complex with TFIIIB and Activates RNA Polymerase III Transcription in Human Cells
CK2 is a highly conserved protein kinase with growth-promoting and oncogenic properties. It is known to activate RNA polymerase III (PolIII) transcription in Saccharomyces cerevisiae and is shown here to also exert a potent effect on PolIII in mammalian cells. Peptide and chemical inhibitors of CK2 block PolIII transcription in human cell extracts. Furthermo
American Society for Microbiology.
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5. Role of the Escherichia coli Nucleotide Excision Repair Proteins in DNA Replication
DNA polymerase I (PolI) functions both in nucleotide excision repair (NER) and in the processing of Okazaki fragments that are generated on the lagging strand during DNA replication. Escherichia coli cells completely lacking the PolI enzyme are viable as long as they are grown on minimal medium. Here we show that viability is fully dependent on the presence
American Society for Microbiology.
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6. Acetylation of TAFI68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription
Mammalian rRNA genes are preceded by a terminator element that is recognized by the transcription termination factor TTF-I. In exploring the functional significance of the promoter-proximal terminator, we found that TTF-I associates with the p300/CBP-associated factor PCAF, suggesting that TTF-I may target histone acetyltransferase to the rDNA promoter. We d
Oxford University Press.
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7. TATA Binding Protein Can Stimulate Core-Directed Transcription by Yeast RNA Polymerase I
The TATA binding protein (TBP) interacts with two transcription factor complexes, upstream activating factor (UAF) and core factor (CF), to direct transcription by RNA polymerase I (polI) in the yeast Saccharomyces cerevisiae. Previous work indicates that one function of TBP is to serve as a bridge, ennabling UAF to recruit and stabilize the binding of CF (2
American Society for Microbiology.
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8. Localization of the yeast RNA polymerase I-specific subunits
The spatial distribution of four subunits specifically associated to the yeast DNA-dependent RNA polymerase I (RNA pol I) was studied by electron microscopy. A structural model of the native enzyme was determined by cryo-electron microscopy from isolated molecules and was compared with the atomic structure of RNA pol II Δ4/7, which lacks the specific poly
Oxford University Press.
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9. Genome of Staphylococcal Phage K: a New Lineage of Myoviridae Infecting Gram-Positive Bacteria with a Low G+C Content
Phage K is a polyvalent phage of the Myoviridae family which is active against a wide range of staphylococci. Phage genome sequencing revealed a linear DNA genome of 127,395 bp, which carries 118 putative open reading frames. The genome is organized in a modular form, encoding modules for lysis, structural proteins, DNA replication, and transcription. Intere
American Society for Microbiology.
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10. Interleukin 6 induces a liver-specific nuclear protein that binds to the promoter of acute-phase genes.
Interleukin 6 (IL-6) is responsible for a variety of biological effects related to the activation of defenses against infection or inflammation, including the immune response and the acute-phase reaction. Its mechanism of action is unknown. It has recently been shown to induce transcription of several genes encoding acute-phase proteins. Here we describe the