Polyethylene Glycols
Mostrando 1-12 de 35 artigos, teses e dissertações.
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1. Preparation and evaluation of azithromycin binary solid dispersions using various polyethylene glycols for the improvement of the drug solubility and dissolution rate
RESUMO A azitromicina é um fármaco insolúvel em água, com biodisponibilidade muito baixa. A fim de aumentar a taxa de solubilidade e dissolução e, consequentemente, aumentar a biodisponibilidade de fármacos fracamente solúveis (tais como azitromicina), várias técnicas podem ser aplicadas. Uma dessas técnicas é a "dispersão sólida", frequentemen
Braz. J. Pharm. Sci.. Publicado em: 2016-03
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2. Effects of polyethylene glycols on intestinal efflux pump expression and activity in Caco-2 cells
O presente estudo foi planejado para investigar a influência de polietileno glicóis sobre a atividade e expressão da P- glicoproteína (P-gp) . Concentrações sub-tóxicas de PGPs e em células Caco-2 foram determinadas por meio do ensaio de MTT. Em seguida, efetuou-se a a medida de captura de Rodamina-123 (Rho-123), um substrato fluorescente de P-gp, em
Braz. J. Pharm. Sci.. Publicado em: 2015-09
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3. Characteristics of hemolytic activity induced by skin secretions of the frog Kaloula pulchra hainana
Background The hemolytic activity of skin secretions obtained by stimulating the frog Kaloula pulchra hainana with diethyl ether was tested using human, cattle, rabbit, and chicken erythrocytes. The skin secretions had a significant concentration-dependent hemolytic effect on erythrocytes. The hemolytic activity of the skin secretions was studied in the pre
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 18/04/2013
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4. Synthesis and MALDI-ToF characterization of dendronized poly(ethylene glycol)s
Híbridos bem definidos de poli(etilenoglicol) lineares (PEGs) e poliésteres dendriméricos foram preparados via "dendronização" de álcool e grupos de PEGs lineares mono e bifuncionais. Embora úteis para a caracterização rudimentar de produtos, Cromatografia por Permeação em Gel e RMN podem não demonstrar a pureza estrutural global desses híbridos
Braz. J. Pharm. Sci.. Publicado em: 2013
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5. L-Hydro treated homologous pulmonary graft vs. pulmonary homograft fresco: an experimental, comparative study / Estudo experimental comparativo do enxerto homólogo pulmonar tratado pelo processo L-Hydro com o homoenxerto pulmonar a fresco
Valve substitutes are highly important in account of their frequent use and since the success of a surgical procedure depends on their good performance. A variety of valve substitutes have been used, all presenting complications pertaining to their materials, such as thrombosis, calcification, degeneration, sterilization difficulties, cost, production comple
Publicado em: 2008
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6. Ação antimicrobiana de diferentes substâncias de uso intracanal / Antimicrobial effect of various intracanal substances
Uma pequena parcela das situações clínicas de infecção endodôntica não responde ao protocolo terapêutico. Para estes casos, sugere-se a administração de uma medicação intracanal alternativa, que apresente amplo espectro de ação e tenha efeito em profundidade no sistema de canais radiculares. Desta forma, este trabalho teve por objetivo avaliar
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/07/2005
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7. Cholesterol-dependent hemolytic activity of Passiflora quadrangularis leaves
Plants used in traditional medicine are rich sources of hemolysins and cytolysins, which are potential bactericidal and anticancer drugs. The present study demonstrates for the first time the presence of a hemolysin in the leaves of Passiflora quadrangularis L. This hemolysin is heat stable, resistant to trypsin treatment, has the capacity to froth, and acts
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-07
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8. Avaliação da radiação gama como agente de imobilização de algumas fases estacionarias sobre suportes para uso em cromatografia gasosa
The liquid stationary phases used in gas chromatography present a serious limitation; their volatility and/ or thermal stability which restrict their use to a specified temperature range. In an attempt to minimize this kind of problem, gamma radiation, in different doses, was used to effectuate immobilization of some liquid stationary phases on supports for
Publicado em: 1989
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9. Bacterial Utilization of Ether Glycols
A soil bacterium capable of using oligo- and polyethylene glycols and ether alcohols as sole sources of carbon for aerobic growth was isolated. The effects of substituent groups added to the ether bonds on the acceptability of the compounds as substrates were studied. Mechanisms for the incorporation of two-carbon compounds were demonstrated by the observati
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10. Degradation of ethylene glycol and polyethylene glycols by methanogenic consortia.
Methanogenic enrichments capable of degrading polyethylene glycol and ethylene glycol were obtained from sewage sludge. Ethanol, acetate, methane, and (in the case of polyethylene glycols) ethylene glycol were detected as products. The sequence of product formation suggested that the ethylene oxide unit [HO-(CH2-CH2-O-)xH] was dismutated to acetate and ethan
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11. Microbial Degradation of Polyethylene Glycols
Mono-, di-, tri-, and tetraethylene glycols and polyethylene glycols (PEG) with molecular weight up to 20,000 were degraded by soil microorganisms. A strain of Pseudomonas aeruginosa able to use a PEG of average molecular weight 20,000 was isolated from soil. Washed cells oxidized mono and tetraethylene glycols, but O2 consumption was not detectable when suc
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12. Polyethylene Glycols as Embedding Media in Histochemical Work