Preimplantation Development
Mostrando 1-12 de 107 artigos, teses e dissertações.
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1. DNA methylation, environmental exposures and early embryo development
Abstract The first crucial step in the developmental program occurs during pre-implantation, the time after the oocyte has been fertilized and before the embryo implants in the uterus. This period represents a vulnerable window as the epigenome undergoes dynamic changes in DNA methylation profiles. Alterations in the early embryonic reprogramming wave can im
Anim. Reprod.. Publicado em: 28/11/2019
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2. Practices and ethical concerns regarding preimplantation diagnosis. Who regulates preimplantation genetic diagnosis in Brazil?
Preimplantation genetic diagnosis (PGD) was originally developed to diagnose embryo-related genetic abnormalities for couples who present a high risk of a specific inherited disorder. Because this technology involves embryo selection, the medical, bioethical, and legal implications of the technique have been debated, particularly when it is used to select fe
Braz J Med Biol Res. Publicado em: 31/10/2014
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3. Effect of exercise on the maternal outcome in pregnancy of spontaneously hypertensive rats
PURPOSE:To evaluate the effect of exercise (swimming) on pregnancy in spontaneously hypertensive rats (SHR).METHODS: Thirty three pregnant female SHR were distributed into three groups (n=11 animals/group): SHR Control=non-exercised (sedentary); SHR Ex0 = exercised from day zero to day 20 of pregnancy; and SHR Ex7 = exercised from day 7 to 20 of pregnancy. B
Acta Cir. Bras.. Publicado em: 2014-09
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4. Mild reproductive effects of the Tityus bahiensis scorpion venom in rats
BackgroundScorpion envenoming is a public health problem in Brazil, whereTityus serrulatus and T. bahiensisare considered the most dangerous scorpions. They are well adapted to urbanized environments, and there is an increasing probability of human exposure to these venoms, including during pregnancy. Not much is known about the effects of prenatal exposure
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 12/02/2014
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5. The gene expression profiles of induced pluripotent stem cells (iPSCs) generated by a non-integrating method are more similar to embryonic stem cells than those of iPSCs generated by an integrating method
Induced pluripotent stem cells (iPSCs) obtained by the ectopic expression of defined transcription factors have tremendous promise and therapeutic potential for regenerative medicine. Many studies have highlighted important differences between iPSCs and embryonic stem cells (ESCs). In this work, we used meta-analysis to compare the global transcriptional pro
Genetics and Molecular Biology. Publicado em: 26/07/2012
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6. Oocyte activation and preimplantation development of bovine embryos obtained by specific inhibition of cyclin-dependent kinases.
Realizaram-se dois experimentos para avaliar a eficiência da bohemina e roscovitina associadas à ionomicina para ativação partenogenética e desenvolvimento embrionário inicial de bovinos. No primeiro, foram testadas diferentes concentrações (0, 50, 75 ou 100µM) e diferentes tempos de exposição (2, 4 ou 6 horas) à bohemina ou à roscovitina na ati
Arquivo Brasileiro de Medicina Veterinaria e Zootecnia.. Publicado em: 2011
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7. Efeitos da exposição crônica à poluição atmosférica particulada sobre o desenvolvimento embrionário pré-implantacional in vitro em camundongos / Effects of chronic exposure to particulate air pollution on in vitro preimplantation embryo development in mice
A thematic research project to evaluate the health effects of acute/chronic exposure to ambient air in a large urban center was developed at the Air Pollution Laboratory in the Department of Pathology at the University of São Paulo School of Medicine. Within this project a specific research line was committed to the study of the effects of this exposure on
Publicado em: 2008
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8. Preimplantation genetic diagnosis of Von Hippel-Lindau disease cancer syndrome by combined mutation and segregation analysis
Von Hippel-Lindau (VHL) disease is an autosomal dominant cancer syndrome, associated with the development of tumors and cysts in multiple organ systems, whose expression and age of onset are highly variable. The VHL disease tumor suppressor gene (VHL) maps to 3p25-p26 and mutations ranging from a single base change to large deletions have been detected in pa
Genetics and Molecular Biology. Publicado em: 2007-03
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9. Expression of the CTCF gene in bovine oocytes and preimplantation embryos
The CCCTC - binding factor (CTCF) is a protein involved in repression, activation, hormone-inducible gene silencing, functional reading of imprinted genes and X-chromosome inactivation. We analyzed CTCF gene expression in bovine peripheral blood, oocytes and in different cellular stages (2-4 cells, 8-16 cells, 16-32 cells, morulae, and blastocysts) of in vit
Genetics and Molecular Biology. Publicado em: 2007
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10. AvaliaÃÃo toxicolÃgica reprodutiva do fitoterÃpico sanativoÂ
The effects of the administration of Sanativo (SAN) were investigated on the pregnancy in Wistar rats. Four groups of female rats (5-8/group) were treated orally with SAN (67, 335 and 1675mg/kg) or water during the pregnancy period (1st to the 21st day) and during each one of the two first phases of pregnancy: pre-implantation (1st to the 6th day) and orga
Publicado em: 2007
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11. Desenvolvimento embrionário em ratas wistar prenhes submetidas ao ultra-som terapêutico de 3 MHz
Therapeutic ultrasound is widely used in different aesthetic treatment by young women, who can be irradiated during early gestation. Researches regarding the effects of therapeutic ultrasound on gestation present controversial results. Methodologies incompatible with clinical aspects are used and different methods and technics were employed. However none of
Publicado em: 2007
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12. Blastocyst-endometrium interaction: intertwining a cytokine network
The successful implantation of the blastocyst depends on adequate interactions between the embryo and the uterus. The development of the embryo begins with the fertilized ovum, a single totipotent cell which undergoes mitosis and gives rise to a multicellular structure named blastocyst. At the same time, increasing concentrations of ovarian steroid hormones
Brazilian Journal of Medical and Biological Research. Publicado em: 22/09/2006