Protein Carbonyls
Mostrando 1-12 de 27 artigos, teses e dissertações.
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1. Antioxidant and immunomodulatory activities of Oviductus ranae in mice
Oviductus ranae (OR) is a traditional Chinese medicine, which was first recorded in the Compendium of Materia Medica in the Ming Dynasty. OR contains high amounts of proteins and elicits therapeutic effects on neurasthenia, insomnia, and respiratory symptoms, which are related to oxidative stress and immunodeficiency. This study aimed to obtain the potential
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
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2. ABA regulation of post-germination desiccation tolerance in wheat cultivars contrasting in drought tolerance
ABSTRACT Post-germination desiccation tolerance (DT) was studied in two wheat cultivars. Effect of pretreatment of abscisic acid (ABA)/ osmotic/ salt/ heat stress was also studied. One day (d)-old seedlings of wheat cultivars PBW 644 (drought tolerant) and PBW 343 (drought susceptible) were exposed to ABA/stress treatment for next 1 d, desiccated for 4 d and
An. Acad. Bras. Ciênc.. Publicado em: 2018-04
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3. Liver Damage Induced by Succinylacetone: A Shared Redox Imbalance Mechanism between Tyrosinemia and Hepatic Porphyrias
To show liver failure mediated by 5-aminolevulinic acid (ALA), a heme precursor accumulated in inborn and acquired porphyrias, rats were treated with succinylacetone methyl ester (SAME). Treated rats underwent the expected ALA accumulation in plasma, liver and urine as a result from inhibition of ALA dehydratase (ALAD) activity. The enzyme activity decreased
J. Braz. Chem. Soc.. Publicado em: 2017-07
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4. "Photo" Chemistry Without Light?
In the early seventies, Giuseppe Cilento (São Paulo University), Emil White (Johns Hopkins University) and Angelo Lamola (AT&T Bell Laboratories) postulated that typical photochemical reactions could occur in dark parts of living organisms if coupled to enzymatic sources of electronically excited products. Their paradoxical hypothesis of "photochemistry wit
J. Braz. Chem. Soc.. Publicado em: 2015-12
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5. Prophylaxis and therapeutic effects of raspberry (Rubus idaeus) on renal stone formation in Balb/c mice
PURPOSE: To evaluate the prophylactic potential of herbal decoction from Rubus idaeus, a medicinal plant widely used in the Middle East to treat kidney stones, by assessing the effect of administration in experimentally induced calcium oxalate (CaOx) nephrolithiasis in mice. MATERIALS AND METHODS: This study was based on administration of glyoxylate and/or h
International braz j urol. Publicado em: 2011-04
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6. BIOCHEMICAL RESPONSE IN CARP (Cyprinus carpio) EXPOSED TO FUNGICIDE TEBUCONAZOLE (FOLICUR 200 EC) / RESPOSTAS BIOQUÍMICAS EM CARPAS (Cyprinus carpio) EXPOSTAS AO FUNGICIDA TEBUCONAZOLE (FOLICUR 200 EC)
The intensive use and/or inadequate management of pesticides have led to contamination of the aquatic ecosystem, reaching the biota living there, including the fish. Pesticides can affect toxicological parameters these animals, harming their survival. In this way, the aim this study has to evaluate biochemistry changes in carps (Cyprinus carpio) after exposu
Publicado em: 2010
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7. Hemodialysis improves endothelial venous function in end-stage renal disease
The objective of the present study was to determine the acute effect of hemodialysis on endothelial venous function and oxidative stress. We studied 9 patients with end-stage renal disease (ESRD), 36.8 ± 3.0 years old, arterial pressure 133.8 ± 6.8/80.0 ± 5.0 mmHg, time on dialysis 55.0 ± 16.6 months, immediately before and after a hemodialysis session,
Publicado em: 2010
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8. Hemodialysis improves endothelial venous function in end-stage renal disease
The objective of the present study was to determine the acute effect of hemodialysis on endothelial venous function and oxidative stress. We studied 9 patients with end-stage renal disease (ESRD), 36.8 ± 3.0 years old, arterial pressure 133.8 ± 6.8/80.0 ± 5.0 mmHg, time on dialysis 55.0 ± 16.6 months, immediately before and after a hemodialysis session,
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-06
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9. Biomarcadores do estado nutricional de ferro e estresse oxidativo em adultos
Objetivo Embora essencial em vários processos vitais no organismo humano, o ferro catalisa reações de geração de espécies reativas de oxigênio, as quais têm sido associadas ao aumento do risco de doenças crônicas não transmissíveis e ao envelhecimento precoce. Este estudo teve por objetivo investigar possíveis correlações e associações entre
Publicado em: 2008
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10. Estresse oxidativo em camundongos knockout para o receptor de LDL : papel dos substratos redutores de NADP+ mitocondrial e dos niveis de Ca POT.2+ intracelular / Oxidative stress in LDL receptor knockout mice : role of NADP+ linked substrates and intracellular Ca POT.2+ levels
In this work, oxidative stress in liver mitochondria isolated from LDLr-/- mice was further characterized by showing a lower mitochondrial isocitrate content, lower matochondrial GSH/GSSG ratio and a higher liver content of protein carbonyls as compared to control mice. The higher rate of ROS production in LDLr -/- mitochondria was also prevented by the pres
Publicado em: 2008
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11. Efeitos da hipercolesterolemia genetica e estatinas sobre a função mitocondrial / Effects of genetic hypercholesteromy and statins on mitochondrial functions
Recent results from our group demonstrated that hypercholesterolemic LDL receptor knockout (LDLR-/-) mice mitochondria possess a lower antioxidant capacity due to a large consumption of reducing equivalents from NADPH to sustain high rates of lipogenesis (Oliveira et al., FASEB J.; 19: 278-280; 2005). In this work, LDLR-/- mice oxidative stress was further c
Publicado em: 2007
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12. Restrição calorica e suplementação com vitamina E no rato submetido ao exercicio fisico exaustivo
The present study was designed to investigate the effects of caloric (carbohydrate) restriction (CR) and vitamin E supplementation on stress oxidative and others exercise-induced metabolic modifications. Male Wistar, eleven-wk old rats were fed control (C)(AIN-93M), or restricted amounts of a modified control (R), or control plus vitamin E (1425 UI of all-ra
Publicado em: 1999