Proteina Tip41
Mostrando 1-2 de 2 artigos, teses e dissertações.
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1. Characterization of the type 2A phosphatase regulatory protein, TIPRL and alpha4 / Caracterização das proteinas TIPRL e alfa4, reguladores de fosfatases 2A
Cells respond constantly to a variety of stimuli, which are interpreted and integrated through signaling networks, giving rise to biological responses. Defects in this circuitry are a cause of many diseases, including cancer. Protein phosphatases are enzymes which remove phosphate groups from kinase substrates, relying mainly on regulatory subunits for their
Publicado em: 2009
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2. Structural analyses of rab family GTPases and mechanism of Mafb regulation by the protein TIPRL / Analises estruturais de GTPases da familia RAB e mecanismo de regulção de MAFB pela proteina TIPRL
GTPases of the Rab family are responsible for the intracellular transport of vesicles. Each family member acts on a specific transport pathway and their function is regulated by GTP binding and hydrolysis, cycling between inactive (GDP-bound) and active (GTP-bound) forms. In this work, we describe the crystal structure of inactive and active forms of the GTP
Publicado em: 2007