Proximal Tubular Function
Mostrando 1-12 de 81 artigos, teses e dissertações.
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1. Effects of sirolimus alone or in combination with cyclosporine A on renal ischemia/reperfusion injury
Calcineurin inhibitors exacerbate ischemic injury in transplanted kidneys, but it is not known if sirolimus protects or exacerbates the transplanted kidney from ischemic injury. We determined the effects of sirolimus alone or in combination with cyclosporin A (CsA) on oxygenated and hypoxic/reoxygenated rat proximal tubules in the following in vitro groups c
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-08
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2. Proximal tubular dysfunction as an indicator of chronic graft dysfunction
New strategies are being devised to limit the impact of renal sclerosis on graft function. Individualization of immunosuppression, specifically the interruption of calcineurin-inhibitors has been tried in order to promote better graft survival once chronic graft dysfunction has been established. However, the long-term impact of these approaches is still not
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-03
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3. Efeito de uma dieta carente em Ãcidos graxos essenciais do desmame a idade adulta sobre aspectos estruturais, funcionais e moleculares renais
Uma dieta equilibrada deve fornecer os nutrientes necessÃrios, inclusive os Ãcidos graxos essenciais (AGE) ao animal, durante toda a vida. O presente trabalho objetivou estudar aspectos funcionais, estruturais e moleculares renais em ratos no crescimento e adultos, em dieta carente em AGE (CAGE) desde o desmame. Os estudos foram realizados em gaiolas metab
Publicado em: 2008
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4. Morfologia e histoquimica do epidismo do gerbilio, Meriones unguiculatus
Epididymidis epithelium of the gerbil (Meriones unguiculatus) was focused in four distinct regions e.g., initial segment, caput, corpus and cauda of the epididymis in which were characterized five cell types: principal, apical, basal, halo and clear cells. These cells were not will characterised on1y in the thin and straight epididymal corpus that showed col
Publicado em: 2004
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5. Estudo da pressão arterial e manipulação renal de sodio em ratos diabeticos induzidos pela administração de estreptozocina : implicações do sistema nitroxidergico
The role ofthe kidney in the control ofhydrosaline homeostasis in patients or experimental models with diabetes mellitus has been striking demonstrated by several studies. Recently, growing evidence suggesting that precocious tubular dysfunction may precede glomerular modifications and influence directly the renal function and cardiovascular homeostase. Howe
Publicado em: 2001
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6. Pressão arterial e manipulação tubular renal de sodio em um modelo de septicemia em ratos
Acute renal failure is a frequent complication in septic patients associated with a high mortality rate. An important characteristic is a decrease in glomerular filtration rate, which is even present in situations where renal blood flow has been maintained. Prevailing hypothesis on the pathogenesis of renal failure suggest an inappropriate and uncontrolled r
Publicado em: 2001
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7. Alterações funcionais, histopatologicas e ultraestruturais renais causadas pelo veneno bruto de Bothrops moojeni (Caiçaca) em ratos vistar
Accidents by snakebites are a common event in tropical countries and it is an important public health problem in Brazil. After envenoming by bothropic and crotalic accidents may include acute renal failure, being it considered the main cause of death. Interposed between the interna I and external milieu and responsible for the organism haemostasy, the kidney
Publicado em: 1998
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8. Proximal and Distal Tubular Function in Salt-Deprived and in Salt-Loaded Deoxycorticosterone Acetate-Escaped Rats
Proximal and distal tubular function was compared with urinary excretion in rats after chronic administration of salt and deoxycorticosterone acetate (DOCA) or during salt deprivation. DOCA rats excreted significantly more sodium than did salt-deprived rats. Measurements of tubular fluid to plasma (TF/P) inulin ratios and concentrations of sodium and potassi
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9. Glomerular and tubular adaptive responses to acute nephron loss in the rat. Effect of prostaglandin synthesis inhibition.
These studies, using in vivo micropuncture techniques in the Munich-Wistar rat, document the magnitude of changes in glomerular and tubular function and structure 24 h after approximately 75% nephron loss (Nx) and compared these results with those obtained in sham-operated rats. The contribution of either nephron hypertrophy or renal prostaglandin to these a
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10. Functional Profile of the Isolated Uremic Nephron: EVIDENCE OF PROXIMAL TUBULAR “MEMORY” IN EXPERIMENTAL RENAL DISEASE
In experimental models of glomerular and nonglomerular renal disease, single nephron filtration rate and proximal tubular reabsorption of fluid decrease or increase in parallel in the same nephron. To assess whether intrinsic adaptations in proximal tubular function, i.e., changes that are independent of the peritubular or humoral milieu, contribute to this
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11. Renal tubular effects of chronic phosphate depletion.
The effects of chronic phosphate depletion on renal tubular function were evaluated by micropuncture and free water clearance studies in the dog. Proximal tubular punctures demonstrated that chronic hypophosphatemia led to a reduction in ratio of tubular fluid to plasma inulin in late superficial tubular from 1.59+/-0.08 in control animals to 1.29+/-0.06 in
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12. Renal tubular dysfunction in patients with inflammatory bowel disease treated with aminosalicylate.
BACKGROUND: An increasing number of case reports indicate potential nephrotoxicity of 5-aminosalicylic acid (5-ASA), which shares similarities with the chemical structures of both phenacetin and acetylsalicylic acid. AIM: In a point prevalence study the occurrence of sensitive indices indicative of early kidney malfunction was assessed in outpatients with in