Pulmonary Surfactants
Mostrando 1-10 de 10 artigos, teses e dissertações.
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1. Efeito de materiais particulados em sistemas modelos de biomembranas / Effect of Particulate Material on Biomembrane Model Systems
This work presents some of the properties of mimetic systems of pulmonary surfactants (PS) composed of dipalmitoylphosphatidylcholine (DPPC) and DPPC/cholesterol and their interactions with particulate material (PM) originated from the burning of sugar cane leaves which is known by clinical studies as an injurious agent of the respiratory airways. The PM des
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/05/2012
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2. Electron magnetic resonance in studies of biologically-relevant systems. / Ressonância magnética eletrônica no estudo de sistemas de interesse biológico
In this work, we made use of the Electron Paramagnetic Resonance (EPR) spectroscopy along with the so-called reporter group technique and extensive spectral simulations by means of the software NLSL to investigate the interaction of nicotine with model membranes. Besides that we also employed Ferromagnetic Resonance (FMR), which is a technique similar in man
Publicado em: 2009
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3. Avaliação da termoestabilidade do surfactante de origem porcina desenvolvido pelo Instituto Butantan utilizando-se o modelo experimental do coelho prematuro / Stability analysis of a surfactant derived from porcine lungs administered to premature newborn rabbits
INTRODUÇÃO: A Síndrome do Desconforto Respiratório (SDR) é uma das principais causas de morbi-mortalidade no período neonatal, acometendo predominantemente os recém-nascidos prematuros, devido a uma está deficiência de surfactante pulmonar. O Instituto Butantan desenvolveu um surfactante de origem porcina com objetivo de torná-lo disponível a todo
Publicado em: 2008
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4. Efeitos da adição de polietilenoglicol ao surfactante exógeno no tratamento da síndrome de aspiração de mecônio em coelhos recém-nascidos / Effects of polyethylene glycol added to exogenous surfactant for meconium aspiration syndrome treatment in newborn rabbits
Meconium is known to be a potent inactivator of pulmonary surfactant, and exogenous surfactant treatment for meconium aspiration syndrome failed to decrease mortality. A number of studies have shown, in vitro, that the addition of polymers such as polyethylene glycol (PEG) to the surfactant maintains good surface activity in the presence of meconium. In the
Publicado em: 2007
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5. Lungs mechanisms and pulmonary function evaluation after polyethyleneglycol addition to the exogenous surfactant in an experimental model of ARDS / "Avaliação dos efeitos da adição do polietilenoglicol ao surfactante pulmonar exógeno na função pulmonar, em um modelo experimental de síndrome de desconforto respiratório tipo agudo"
O surfactante pulmonar é uma substância fundamental na mecânica pulmonar, com atividade biofísica e de proteção alveolar por reduzir a tensão superficial e impedir o seu colabamento.Na síndrome do desconforto respiratório tipo agudo(SDRA) ocorre uma diminuição quantitativa e disfunção qualitativa do surfactante com agravamento do quadro clínico
Publicado em: 2005
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6. Water repellency induced by pulmonary surfactants.
1. Pure cotton fabric was partially carboxylated to produce a tough, porous, hydrophilic sub-phase to stimulate the epithelial membrane of the alveolar wall from a permeability standpoint. 2. Two of the predominant pulmonary surfactants, dipalmitoyl lecithin (DPL) and dipalmitoyl phosphatidylethanolamine (DPPE), were found to inhibit wetting of this syntheti
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7. Charge of the Surfactants♦: Anionic Pulmonary Surfactant Phospholipids Inhibit Inflammatory Responses from Alveolar Macrophages and U937 Cells by Binding the Lipopolysaccharide-interacting Proteins CD14 and MD-2
American Society for Biochemistry and Molecular Biology.
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8. Pulmonary surfactant: hydrophobic nature of the mucosal surface of the human amnion.
The contact angle has been measured for a drop of saline placed upon the rinsed mucosal surface of the amnion in eleven human placental membranes obtained from normal births at full term. The contact angle averaged 70 degrees, indicating a hydrophobic surface comparable with graphite (86 degrees), polyethylene (94 degrees) or oxyntic tissue (85 degrees) whic
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9. Reversible Formation of Nanodomains in Monolayers of DPPC Studied by Kinetic Modeling
Dipalmitoylphosphatidylcholine (DPPC) is the most abundant component in pulmonary surfactants and is believed to be responsible for maintaining low surface tension in alveoli during breathing. In this work, a kinetic model is introduced that describes the phase separation in DPPC films that produces the liquid-condensed (LC) and liquid-expanded (LE) fraction
The Biophysical Society.
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10. cDNA and deduced amino acid sequence of human pulmonary surfactant-associated proteolipid SPL(Phe).
Hydrophobic surfactant-associated protein of Mr 6000-14,000 was isolated from ether/ethanol or chloroform/methanol extracts of mammalian pulmonary surfactant. Automated Edman degradation in a gas-phase sequencer showed the major N-terminus of the human low molecular weight protein to be Phe-Pro-Ile-Pro-Leu-Pro-Tyr-Cys-Trp-Leu-Cys-Arg-Ala-Leu-. Because of the