Rank Fusion
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Um modelo de fusão de rankings baseado em análise de preferência / A model to ranking fusion based on preference analysis
O crescente volume de informações disponíveis na rede mundial de computadores, gera a necessidade do uso de ferramentas que sejam capazes de localizá-las e ordenálas, de forma cada vez mais precisa e que demandem cada vez menos recursos computacionais. Esta necessidade tem motivado pesquisadores a estudar e desenvolver modelos e técnicas que atendam es
Publicado em: 2009
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2. Expression of active BCR related (ABR) gene in chronic myeloid leukemia (CML) real-time RT-PCR (qPCR) / Estudo da expressão do Gene ABR em leucemia mieloide cronica (LMC) utilizando real-time RT-PCR (qPCR)
Chronic myeloid leukemia (CML) is a clonal proliferative disorder of the hematopoietic stem cell cytogenetically characterized by the Philadelphia (Ph) chromosome, a result of chromosomal translocation t(9;22)(q34;q11). At molecular level, the Ph chromosome results in a fusion gene, the chimerical BCR-ABL which has constitutive tyrosine kinase activity and i
Publicado em: 2006
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3. Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand
A receptor that mediates osteoprotegerin ligand (OPGL)-induced osteoclast differentiation and activation has been identified via genomic analysis of a primary osteoclast precursor cell cDNA library and is identical to the tumor necrosis factor receptor (TNFR) family member RANK. The RANK mRNA was highly expressed by isolated bone marrow-derived osteoclast pr
The National Academy of Sciences.
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4. Responses to toxicants of an Escherichia coli strain carrying a uspA'::lux genetic fusion and an E. coli strain carrying a grpE'::lux fusion are similar.
A transcriptional fusion of the Escherichia coli uspA promoter to luxCDABE was characterized and compared with a heat shock-responsive grpE'::lux fusion. Similarities in range and rank order of inducing conditions were observed; however, the magnitude of induction was typically greater for the grpE'::lux fusion strain.
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5. Selection of the best target site for ribozyme-mediated cleavage within a fusion gene for adenovirus E1A-associated 300 kDa protein (p300) and luciferase.
The cellular 300 kDa protein known as p300 is a target for the adenoviral E1A oncoprotein and it is thought to participate in prevention of the G0/G1 transition during the cell cycle, in activation of certain enhancers and in the stimulation of differentiation pathways. In order to determine the exact function of p300, as a first step we constructed a simple
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6. Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.
Philadelphia chromosome-positive leukemias result from the fusion of the BCR and ABL genes, which generates a functional chimeric molecule. The Abr protein is very similar to Bcr but lacks a structural domain which may influence its biological regulatory capabilities. Both Abr and Bcr have a GTPase-activating protein (GAP) domain similar to those found in ot
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7. The Epstein-Barr Virus Thymidine Kinase Does Not Phosphorylate Ganciclovir or Acyclovir and Demonstrates a Narrow Substrate Specificity Compared to the Herpes Simplex Virus Type 1 Thymidine Kinase
The Epstein-Barr virus (EBV) thymidine kinase (TK) was expressed in mammalian 143B TK− cells to investigate its substrate specificity. The herpes simplex virus type 1 (HSV-1) TK was similarly expressed for comparison. Both viral TKs conferred a TK+ phenotype on 143B TK− cells. The nucleoside analog ganciclovir (GCV) did not affect the growth of 143B EBV
American Society for Microbiology.
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8. Bovine papillomavirus type 1 E2 transcriptional regulators directly bind two cellular transcription factors, TFIID and TFIIB.
The bovine papillomavirus type 1 (BPV-1) E2 translational open reading frame encodes three proteins that regulate viral transcription and DNA replication: the E2 transcriptional activator (E2TA), the E2 transcriptional repressor (E2TR) and the E8/E2 transcriptional repressor (E8/E2TR). E2TA is a strong activator of papillomaviral promoters and is required fo