Reaction Time Drug Effects
Mostrando 1-12 de 20 artigos, teses e dissertações.
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1. Analgesic and antiinflammatory activities of the essential oil from Artemisia sieberi Besser
The analgesic activity of Artemisia sieberi oil was assessed by acetic acid-induced writhing test and Eddy’s hot plate method; while the acute anti-inflammatory effect was investigated by inflammatory paw edema test in rats. The administration rout of the essential oil, standard drugs and the vehicle used in all assays was intraperitoneal injection. The 1
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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2. Reações adversas ao benzonidazol no tratamento da Doença de Chagas: revisão sistemática de ensaios clínicos randomizados e controlados
Resumo Introdução No Brasil, a única droga disponível para o tratamento específico do Trypanosoma cruzi, causador da Doença de Chagas (DC) é o Benzonidazol (BZN), cujas reações adversas podem propiciar a interrupção do tratamento. Objetivo O objetivo desse trabalho é quantificar a proporção de ocorrência de efeitos adversos, descrevê-los e
Cad. saúde colet.. Publicado em: 30/09/2019
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3. Antimony resistance in Leishmania (Viannia) braziliensis clinical isolates from atypical lesions associates with increased ARM56/ARM58 transcripts and reduced drug uptake
BACKGROUND In addition to the limited therapeutic arsenal and the side effects of antileishmanial agents, drug resistance hinders disease control. In Brazil, Leishmania braziliensis causes atypical (AT) tegumentary leishmaniasis lesions, frequently refractory to treatment. OBJECTIVES The main goal of this study was to characterise antimony (Sb)-resistant
Mem. Inst. Oswaldo Cruz. Publicado em: 15/08/2019
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4. Evaluation of the safety and satisfaction of rheumatic patients with accelerated infliximab infusion
Abstract Introduction: Infliximab infusion generally occurs in 2–4 h. Recent studies have suggested the possibility of accelerated infusion (1 h) of this drug. Objective: To evaluate the safety of accelerated infliximab infusion in patients with rheumatic diseases. In addition, patient satisfaction was also assessed. Methods: A prospective, single-cente
Adv. rheumatol.. Publicado em: 29/07/2019
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5. Box–Behnken experimental design for extraction of artemisinin from Artemisia annua and validation of the assay method
ABSTRACT Obtaining artemisinin and its derivatives is very costly, which limits access to low-income people. Some hydroalcoholic extract of Artemisia annua L., Asteraceae, which has shown comparable antimalarial activity could be an alternative to the purified compound, especially if the cultivars have higher content of artemisinin. The objective of this stu
Rev. bras. farmacogn.. Publicado em: 2017-08
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6. Determination of Aspirin Using Chemiluminescence System of Tris(1,10 phenanthroline)Ruthenium(II)-Cerium(IV)
A new chemiluminescence (CL) method has been proposed for the simple determination of aspirin (acetylsalicylic acid, ASA). The method is based on the enhancement effect of ASA in the CL reaction of tris(1,10 phenanthroline)ruthenium(II), Ru(phen)32+, with cerium(IV) (CeIV) in acidic medium. Under optimum conditions, the CL intensity was proportional to the c
J. Braz. Chem. Soc.. Publicado em: 2016-03
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7. Degradação fotocatalítica de rosuvastatina em solução aquosa empregando ZnO em suspensão : cinética, subprodutos e toxicidade
The photocatalytic degradation of Rosuvastatin, a drug used to reduce blood cholesterol levels, employing ZnO as catalyst was studied in this work. The experiments were carried out in a UV irradiated batch reactor, equipped with temperature control. The effect of catalyst concentration, initial pH and initial Rosuvastatin concentration were evaluated. Photol
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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8. Analise dos efeitos e dos mecanismos de ação do fator de crescimento transformante- beta 1, interferon gama e iclosporina A na transdiferenciação dos fibroblastos gengivais em miofibroblastos / Effects of transforming growth factor- beta 1, interferon gamma and cyclosporin A on transdifferentiation of gingival fibroblasts in myofibroblasts
Myofibroblasts are the main cellular type involved in extracellular matrix deposition in fibrotic diseases. Relatively little is known about the underlying mechanisms that regulate myofibroblast emergence (transdifferentiation), however the regulatory cytokine transforming growth factor-beta 1 (TGF- beta 1) has been traditionally considered an inducer of the
Publicado em: 2007
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9. "Flutuação da atenção na doença de Parkinson" / Fluctuation of attention in Parkinson s disease
Para avaliar a influencia em curto prazo da reposição dopaminérgica na flutuação da atenção em pacientes com DP, a latência média e o desvio-padrão da latência do tempo de reação simples e com escolha foram estabelecidos em 15 pacientes com DP antes e 90 minutos depois da administração da dose habitual matutina de levodopa e em 15 controles no
Publicado em: 2006
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10. The inactivation of the basolateral nucleus of the rat amygdala has an anxiolytic effect in the elevated T-maze and light/dark transition tests
Pharmacological evidence indicates that the basolateral nucleus of the amygdala (BLA) is involved in the mediation of inhibitory avoidance but not of escape behavior in the elevated T-maze test. These defensive responses have been associated with generalized anxiety disorder (GAD) and panic disorder, respectively. In the present study, we determined whether
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-11
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11. Estudos sobre o antineoplasico CPT-11 : I. Interação com albumina de soro humano (HSA) ; II. Encapsulação e caracterização de CPT-11 em lipossomas estericamente estabilizados
This project was motivated by the prospects of both an improvement in the efficacy of anticancer drugs and a reduction in their side effects as a result of being encapsulated in liposomes. The first part of this work consisted in the study of the interaction between the antineoplasic drug CPT-11 and Human Serum Albumin (HSA), in order to evaluate the stabili
Publicado em: 2002
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12. Estudo farmacolÃgico da ternatina, um flavonÃide isolado de Egletes viscosa, LESS / FarmacolÃgico study of the ternatina, an isolated flavonÃide of Egletes viscose, LESS
Ternatin (5, 4â-dihydroxy-3, 7, 8, 3â-tetrametoxy-flavone), a flavonoid which was extracted and purified from Egletes viscosa, Less. (Compositae), was screened for various pharmacological effects in experimental animals. The compound (15 and 30 mg/kg, i.p.) demonstrated a dose-related significant anti- inflammatory effect in the carrageenan-induced rat hin
Publicado em: 1991