Retinitis Pigmentosa
Mostrando 1-12 de 224 artigos, teses e dissertações.
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1. Effects and mechanisms of water-soluble Semen cassiae polysaccharide on retinitis pigmentosa in rats
Abstract This study aimed to investigate the effects and mechanisms of water-soluble Semen cassiae polysaccharide (SCP) on retinitis pigmentosa (RP) in rats. One hundred rats were randomly divided into control, model, and 50, 100 and 200 mg/kg SCP groups. The 50, 100 and 200 mg/kg SCP groups were treated with 50, 100 and 200 mg/kg SCP for 5 days, respectivel
Food Sci. Technol. Publicado em: 2020-03
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2. Anterior chamber characteristics assessed by rotating Scheimpflug imaging in patients with retinitis pigmentosa
RESUMO Objetivo: Este estudo visou avaliar parâmetros do segmento anterior e aberrações corneanas em pacientes com retinite pigmentosa através de imagens de Scheimpflug e comparar os achados com os de controles saudáveis. Métodos: Este foi um estudo caso-controle unicêntrico que incluiu pacientes com o diagnóstico de retinite pigmentosa em acompanh
Arq. Bras. Oftalmol.. Publicado em: 12/09/2019
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3. Effects and mechanisms of water-soluble Semen cassiae polysaccharide on retinitis pigmentosa in rats
Abstract This study aimed to investigate the effects and mechanisms of water-soluble Semen cassiae polysaccharide (SCP) on retinitis pigmentosa (RP) in rats. One hundred rats were randomly divided into control, model, and 50, 100 and 200 mg/kg SCP groups. The 50, 100 and 200 mg/kg SCP groups were treated with 50, 100 and 200 mg/kg SCP for 5 days, respectivel
Food Sci. Technol. Publicado em: 15/07/2019
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4. Retinal dystrophies and variants in PRPH2
RESUMO | Este relato apresenta três pacientes com diagnóstico de distrofias maculares com mutações no PRPH2. Periferina 2, a proteína deste gene, é importante na morfogênese e estabilização do segmento externo dos fotorreceptores. Deficiências de periferina 2 causam apoptose celular. Além disso, variantes patogênicas no PRPH2 estão relacionadas
Arq. Bras. Oftalmol.. Publicado em: 2019-03
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5. Finding new approaches to treat retinitis pigmentosa caused by mutations in the photoreceptor rhodopsin. / Em busca de novos métodos de tratamento para a retinose pigmentar causada por mutações na rodopsina.
Retinitis Pigmentosa (RP) is an inherited disease that progressively leads to blindness. More than 150 mutations associated with RP are known in rhodopsin, causing its misfolding. This thesis tested the hypothesis that small molecules can rescue folded rhodopsin and/or reduce photoreceptor cell death. RP mutations, N15S and P23H, revealed differences in char
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/07/2012
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6. Caracterização das principais mutações de ponto do DNA mitocondrial em um grupo de pacientes com doenças neurodegenerativas
Mitochondrial disease are genetic and clinic heterogeneous entities that are variable in age of onset, clinical severity and evolution. They are classified in abnormalities of nuclear DNA or mitochondrial DNA (mtDNA). Point mutations are found in mitochondrial genomes and most frequent phenotypes are MELAS (mitochondrial encephalomyopathy, lactic acidosis, a
Publicado em: 2002
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7. Pupil size following dark adaptation in patients with retinitis pigmentosa
According to the equivalent light hypothesis, molecular defects in the photoreceptor lead to a continuous activation of the photoreceptor cascade in a manner equivalent to real light. The consequences in diseases such as retinitis pigmentosa (RP) are as disruptive to the cells as real light. Two forms of the equivalent light hypothesis can be distinguished:
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-08
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8. Selective degeneration of photoreceptors in retinal tissue in vitro: a new experimental model for retinitis pigmentosa
Anais da Academia Brasileira de Ciências. Publicado em: 2000-09
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9. Clinical copper metabolism parameters in patients with retinitis pigmentosa and other tapeto-retinal degenerations.
Reports have appeared of abnormal copper metabolism in retinitis pigmentosa, and of a family with vitelliform retinal degeneration in which other members suffered from hepatolenticular degeneration. In the present study 15 patients with retinitis pigmentosa, 4 with various other retinal degenerations, and 1 with a family disposition to retinitis pigmentosa w
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10. Contrast sensitivity in retinitis pigmentosa.
Arden gratings were used to measure contrast sensitivity in 40 patients with retinitis pigmentosa whose Snellen visual acuity was 6/12 or better. When compared with a group of 30 normal subjects the patients with retinitis pigmentosa had substantially decreased contrast sensitivity, especially at high frequencies. The Arden grating test appeared to be a sens
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11. The association of retinitis pigmentosa with preretinal macular gliosis.
A retrospective study of the histopathological features of retinitis pigmentosa was undertaken. A consistent finding in 10 out of 10 eyes from 6 patients with retinitis pigmentosa was the presence of a preretinal membrane. The frequency of this finding has not been noted previously. Preretinal gliosis may well be responsible for the production of the abnorma
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12. The incidence of HLA-SD antigens in recessive retinitis pigmentosa.
Eighteen patients with recessive retinitis pigmentosa were tissue typed for HLA-SD antigens. There was no evidence that a particular HLA-SD antigen was associated with autosomal recessive retinitis pigmentosa.