Ribonucleoprotein
Mostrando 1-12 de 1201 artigos, teses e dissertações.
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1. Trypanosoma cruzi XRNA granules colocalise with distinct mRNP granules at the nuclear periphery
BACKGROUND Eukaryotic ribonucleoprotein (RNP) granules are important for the regulation of RNA fate. RNP granules exist in trypanosomatids; however, their roles in controlling gene expression are still not understood. XRNA is a component of granules in Trypanosoma brucei but has not been investigated in Trypanosoma cruzi. OBJECTIVES This study aimed to inv
Mem. Inst. Oswaldo Cruz. Publicado em: 18/06/2018
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2. RNA-binding proteins and their role in the regulation of gene expression in Trypanosoma cruzi and Saccharomyces cerevisiae
Abstract RNA-binding proteins (RBPs) have important functions in the regulation of gene expression. RBPs play key roles in post-transcriptional processes in all eukaryotes, such as splicing regulation, mRNA transport and modulation of mRNA translation and decay. RBPs assemble into different mRNA-protein complexes, which form messenger ribonucleoprotein compl
Genet. Mol. Biol.. Publicado em: 2017-03
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3. Variabilidade no reconhecimento de padrões de imunofluorescência indireta em diferentes marcas de lâminas HEp-2
INTRODUÇÃO: A imunofluorescência indireta (IFI) utilizando células HEp-2 como substrato antigênico é o teste padrão-ouro para a pesquisa de autoanticorpos contra antígenos celulares. Contudo, as condições de cultivo, fixação e permeabilização celular interferem diretamente na preservação e na distribuição espacial dos antígenos. Portanto,
J. Bras. Patol. Med. Lab.. Publicado em: 2013-06
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4. Immunogenicity of influenza H1N1 vaccination in mixed connective tissue disease: effect of disease and therapy
OBJECTIVE: To assess the potential acute effects regarding the immunogenicity and safety of non-adjuvanted influenza A H1N1/2009 vaccine in patients with mixed connective tissue disease and healthy controls. METHODS: Sixty-nine mixed connective tissue disease patients that were confirmed by Kasukawa's classification criteria and 69 age- and gender-matched co
Clinics. Publicado em: 2013
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5. Lupus eritematoso neonatal: reporte de cuatro casos
Neonatal lupus erythematosus is a very rare disease, clinically characterized by skin lesions that resemble those of subacute or discoid lupus erythematosus and/or congenital heart block. Generally, when patients have skin manifestations, they have no cardiac defects and vice-versa; however, in 10% of cases these manifestations may coexist. Other findings ma
Anais Brasileiros de Dermatologia. Publicado em: 2011-04
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6. Efeitos da radiação gama na imunogenicidade das ribonucleoproteínas (RNPs) do vírus da raiva e purificação de anticorpos anti-RNPs para diagnóstico / Effects of gamma radiation immunogenicity of ribonucleoprotein (RNPs) of rabies virus and purification of anti-RNPs antibodies for diagnosis
A Organização Mundial da Saúde recomenda o teste de Imunofluorescência Direta (IFD) para a realização do Diagnóstico Laboratorial e Avaliação Sorológica da raiva. Como reveladores deste teste, são utilizados conjugados fluorescentes antirribonucleoproteínas (RNPs) do vírus da raiva, produzidos a partir de anticorpos anti-RNPs obtidos da purifica
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/08/2010
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7. Ultrastructural description of rabies virus infection in cultured sensory neurons
Primary cultures were made from adult mouse spinal ganglia for depicting an ultrastructural description of rabies virus (RABV) infection in adult mouse sensory neuron cultures; they were infected with rabies virus for 24, 36, and 48 h. The monolayers were processed for transmission electron microscopy and immunochemistry studies at the end of each period. As
Memórias do Instituto Oswaldo Cruz. Publicado em: 19/04/2007
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8. Cloning and molecular characterization of Trypanosoma cruzi U2, U4, U5, and U6 small nuclear RNAs
Small nuclear RNAs (snRNAs) are important factors in the functioning of eukaryotic cells that form several small complexes with proteins; these ribonucleoprotein particles (U snRNPs) have an essential role in the pre-mRNA processing, particularly in splicing, catalyzed by spliceosomes, large RNA-protein complexes composed of various snRNPs. Even though they
Memórias do Instituto Oswaldo Cruz. Publicado em: 2007-02
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9. Capilaroscopia na DMTC: um processo dinâmico associado ao envolvimento intersticial pulmonar e à gravidade de doença / Capillaroscopy in MCTD: a dynamic process associated to lung interstitial involvement and disease severity
For determining the clinical relevance of SD-pattern in MCTD, sixty-three MCTD patients (Kasukawa´s criteria) were consecutively selected. The main inclusion criterion was availability of previous nailfold capillaroscopy (NC) 5 years before inclusion. At entry, organ involvement and autoantibody evaluation were performed. The mean age and disease duration w
Publicado em: 2006
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10. Análise estrutural e funcional de cofatores do exossomo em Saccharomyces cerevisiae e Pyrococcus / Structural and functional analysis of exosome cofactors in Saccharomyces cerevisiae and Pyrococcus
A síntese ribossomal é uma das maiores atividades em células eucarióticas. Este processo inicia-se no nucléolo e é finalizado após a exportação das subunidades 40S e 60S para o citoplasma. Três dos RNAs ribossomais de eucariotos (18S, 5.8S e 25S) são sintetizados como um transcrito primário de 35S, o qual é processado através de uma complexa e
Publicado em: 2006
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11. Presence of autoantibodies against HeLa small nuclear ribonucleoproteins in chagasic and non-chagasic cardiac patients
We detected anti-human small nuclear ribonucleoprotein (snRNP) autoantibodies in chagasic patients by different immunological methods using HeLa snRNPs. ELISA with Trypanosoma cruzi total lysate antigen or HeLa human U small nuclear ribonucleoproteins (UsnRNPs) followed by incubation with sera from chronic chagasic and non-chagasic cardiac patients was used
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-01
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12. Assembly of avian reticuloendotheliosis virus: association of the core precursor polypeptide with the intracellular ribonucleoprotein complex.
A virus-specific ribonucleoprotein complex is present in the cytoplasm of reticuloendotheliosis virus-transformed chicken bone marrow cells. This ribonucleoprotein complex contains viral reverse transcriptase activity and may represent a precursor to the budding virion. The major viral polypeptide associated with the ribonucleoprotein complex was a polypepti