Sclerosing Adenosis
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Estudo de Danos Oxidativos Espontâneos no DNA de Pacientes com Lesões Malignas e Benignas de Mama. / Spontaneous Oxidative Damage in DNA of Patients with Malignant and Benign Breast Lesions.
O estresse oxidativo é um dos principais responsáveis pela produção de danos espontâneos no DNA, os quais podem levar à origem de diversas neoplasias, inclusive câncer de mama (CM). Além disso, dentre os diversos fatores de risco já estabelecidos para a ocorrência do CM em mulheres, como idade, hormônios, dieta e fatores genéticos, alguns tipos d
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 04/11/2011
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2. Avaliação imunoistoquimica de celulas mioepiteliais no diagnostico diferencial de lesões benignas e malignas da mama / Immunohistochemical assessment of myoepithelial cells in the differential diagnosis of benign and malignant lesions of the breast
O sistema ductal da mama é revestido por duas camadas de células: uma constituída de células epiteliais luminais e outra de células mioepiteliais (CME). A identificação das CMEs é de grande importância na rotina em patologia cirúrgica, já que estas estão presentes em lesões benignas e geralmente ausentes nas malignas. Contudo, esta identificaç�
Publicado em: 2006
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3. Basement membrane and apocrine epithelial antigens in differential diagnosis between tubular carcinoma and sclerosing adenosis of the breast.
The distributions of defined basement membrane proteins in nine pure tubular carcinomas, 10 cases of sclerosing adenosis, and 15 ductal adenocarcinomas were compared. Sections of formalin fixed, paraffin embedded specimens were pretreated with pepsin and then immunostained for laminin, type IV collagen, and basement membrane proteoglycan, components specific
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4. A Study of Surgically Removed Specimens of Breast, with Special Reference to Sclerosing Adenosis
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5. Upregulation of ATM in sclerosing adenosis of the breast.
The gene mutated in ataxia telangiectasia (ATM) has an established tumour suppressor role in breast cancer. ATM appears to be expressed in most normal cells, including breast epithelium, where it has been postulated to have a nuclear role in cell cycle regulation following DNA damage. However, ATM is not upregulated after DNA damage. In this study, we demons
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6. Apocrine adenosis: a precursor of aggressive breast cancer?
AIM--To investigate overexpression of c-erbB2, expression of the p53 protein product and proliferation rates in benign breast lesions with specific reference to apocrine adenosis. METHODS--Twenty one cases of apocrine adenosis were stained with monoclonal antibodies to p185, the protein product of the c-erbB2 oncogene, the protein product of the p53 tumour s
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7. Non‐operative breast pathology: apocrine lesions
Apocrine metaplasia is a very common finding in the female breast after the age of 25. It is so common that many people regard it as a normal component of the breast. This, however, is only really the case in apocrine sweat glands of the axilla and in the peri‐areolar apocrine glands. The apocrine cell does, however, contribute to a number of different bre
BMJ Group.
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8. Monoclonal antibody B72.3 in benign breast lesions.
It has been suggested that the monoclonal antibody B72.3 may be useful as a diagnostic tool in fine needle aspirates of breast masses because it recognises "tumour associated glycoprotein (TAG)-72". The antigen was sought in paraffin wax sections of 43 normal and benign breast biopsy specimens, using the avidin-biotin complex technique, to assess the extent