Secretion Chaperones
Mostrando 1-12 de 53 artigos, teses e dissertações.
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1. Immunoproteomics of Plasmodium falciparum-infected red blood cell membrane fractions
BACKGROUND The surface of infected red blood cells (iRBCs) has been widely investigated because of the molecular complexity and pathogenesis mechanisms involved. Asymptomatic individuals are important in the field because they can perpetuate transmission as natural reservoirs and present a challenge for diagnosing malaria because of their low levels of circ
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-12
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2. The F309S mutation increases factor VIII secretion in human cell line
ABSTRACT OBJECTIVES: The capacity of a human cell line to secrete recombinant factor VIII with a F309S point mutation was investigated, as was the effect of the addition of chemical chaperones (betaine and sodium-4-phenylbutyrate) on the secretion of factor VIII. METHODS: This work used a vector with a F309S mutation in the A1 domain to investigate FVIII
Rev. Bras. Hematol. Hemoter.. Publicado em: 2016-06
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3. Characteristics of dr1790 disruptant and its functional analysis in Deinococcus radiodurans
Deinococcus radiodurans (DR) is an extremophile that is well known for its resistance to radiation, oxidants and desiccation. The gene dr1790 of D. radiodurans was predicted to encode a yellow-related protein. The primary objective of the present study was to characterize the biological function of the DR1790 protein, which is a member of the ancient yellow/
Braz. J. Microbiol.. Publicado em: 2015-06
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4. Estudos biofísicos de chaperonas de secreção e de interações proteína-ligante / Biophysical studies on secretion chaperones and protein-ligand interactions
So far, the Xanthomonas axonopodis pv. citri (XAC) mechanisms of bacterial virulence is unknown. It is believed that secretion chaperones (CS) are involved in the XAC´s virulence process by first forming complexes with virulence factors, and assisting in their presentation to corresponding secretion systems using ATP as a source of energy. Fluorescence emis
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/03/2012
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5. Resolução estrutural de proteínas hipotéticas, chaperonas de secreção, da bactéria Xanthomonas axonopodis pv. citri / Structural insights on hypothetical proteins, secretion chaperones from Xanthomonas axonopodis pv. citri
O presente estudo teve por objetivo a caracterização estrutural de quatro possíveis chaperonas de secreção da bactéria Xanthomonas axonopodis pv. citri (Xac). Esta caracterização é importante para entender as funções destas proteínas e consequentemente compreender os mecanismos de virulência da Xac que é a causadora do cancro cítrico. Das quat
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/09/2011
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6. Análise de chaperonas hipotéticas da Xanthomonas axonopodis pv. citri por espectrometria de massas / Mass spectrometry analysis of secretion chaperones from Xanthomonas axonopodis pv. citri
A expressão protéica da bactéria Xanthomonas axonopodis pv. citri (Xac) foi avaliada aplicando técnicas de espectrometria de massas (MS) na tentativa de identificar a presença de 40 proteínas classificadas como possíveis chaperonas de secreção dos Sistemas Secretórios do Tipo III e IV. Embora o processo de virulência da Xac ainda não seja bem elu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/10/2010
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7. Identificação e caracterização de chaperones de secreção no genoma do fitopatógeno Xanthomonas axonopodis patovar citri / Identification and characterization of secretion chaperones in the phytopathogen Xanthomonas axonopodis patovar citri
A anotação automática de genes através do sequenciamento completo do genoma de um patógeno possibilita estudar e compreender a biologia e os mecanismos de infecção, proporcionando sistemas de controle e tratamento de pragas e doenças. Genes são anotados por homologia e as informações gerais obtidas fornece indicações sobre a filognia do organism
Publicado em: 2006
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8. In silico identification of potential chaperone genes that belong to type III and type IV secretion systems in Xanthomonas axonopodis pv citri
The secretion of bacterial virulence factors and flagellar components requires the assistance of specific type III and flagellar chaperones. Standard computational annotation of the genome of Xanthomonas axonopodis pv citri, a plant pathogen that causes citrus canker, initially did not identify any genes belonging to these chaperone categories since the prim
Genetics and Molecular Biology. Publicado em: 2005
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9. Three pure chaperone proteins of Escherichia coli--SecB, trigger factor and GroEL--form soluble complexes with precursor proteins in vitro.
Diverse studies of three cytoplasmic proteins of Escherichia coli--SecB, trigger factor and GroEL--have suggested that they can maintain precursor proteins in a conformation which is competent for membrane translocation. These proteins have been termed 'chaperones'. Using purified chaperone proteins and precursor protein substrates, we find that each of thes
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10. Immunoglobulin-like PapD chaperone caps and uncaps interactive surfaces of nascently translocated pilus subunits.
Molecular chaperones are found in the cytoplasm of bacteria and in various cellular compartments in eukaryotes to maintain proteins in nonnative conformations that permit their secretion across membranes or assembly into oligomeric structures. Virtually nothing, however, has been reported about a similar requirement for molecular chaperones in the periplasm
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11. Influence of impaired chaperone or secretion function on SecB production in Escherichia coli.
The efficient export of proteins through the cytoplasmic membrane of Escherichia coli requires chaperones to maintain protein precursors in a translocation-competent conformation. In addition to SecB, the major chaperone facilitating export of particular precursors, heat shock-induced chaperones DnaK-DnaJ and GroEL-GroES are also involved in this process. By
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12. Translocated Intimin Receptor and Its Chaperone Interact with ATPase of the Type III Secretion Apparatus of Enteropathogenic Escherichia coli
Few interactions have been reported between effectors and components of the type III secretion apparatus, although many interactions have been demonstrated between type III effectors and their cognate chaperones. It is thought that chaperones may play a role in directing effectors to the type III secretion apparatus. The ATPase FliI in the flagellar assembly
American Society for Microbiology.