Selective Nsaid
Mostrando 1-12 de 15 artigos, teses e dissertações.
-
1. Effects of Selective Versus Non-Selective COX-2 Inhibition on Experimental Periodontitis
Resumo No presente estudo nós comparamos os efeitos de um inibidor seletivo da COX-2 (etoricoxibe) com um anti-inflamatório não esteroidal não seletivo (AINE) (diclofenaco de potássio) no processo inflamatório e perda óssea alveolar em modelo de periodontite experimental. Noventa ratos Holtzman machos (250 g) foram randomizados em quatro grupos experi
Braz. Dent. J.. Publicado em: 04/04/2019
-
2. The influence of non-steroidal anti-inflammatory drugs and paracetamol used for pain control of orthodontic tooth movement: a systematic review
ABSTRACT The present study aimed to perform a systematic literature review to determine if there is a non-steroidal anti-inflammatory drug (NSAID) that interferes less within tooth movement. This research was performed according to the PRISMA statement. Articles were searched in eight electronic databases (PubMed, Scopus, Embase, Web of Science, LILACS, SciE
An. Acad. Bras. Ciênc.. Publicado em: 31/08/2017
-
3. Gastric and renal effects of COX-2 selective and non-selective NSAIDs in rats receiving low-dose aspirin therapy
Abstract The consumption of low-dose aspirin (LDA) to prevent cardiovascular disease continues to increase worldwide. Consequently, the number of chronic LDA users seeking dental procedures that require complementary acute anti-inflammatory medication has also grown. Considering the lack of literature evaluating this interaction, we analyzed the gastric and
Braz. oral res.. Publicado em: 28/11/2016
-
4. Alterações hematológicas, hemostáticas e bioquímicas de cães tratados com anti-inflamatórios não esteroidais / Hematological, hemostatic and biochemical effects on nonsteroidal anti-inflammatory therapy in dogs
This study aimed to evaluate the heart and liver biomarkers, hematology and hemostasis in healthy dogs, submitted to therapy with nonsteroidal anti-inflammatory non-selective (NSAID), COX-2 preferential and COX-2 selective drugs. Were used 30 mongrel dogs, adults, males and females, clinically healthy, randomly divided into 5 groups (G) of 6 animals, that re
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/09/2011
-
5. Efficacy and safety of parecoxib in the treatment of acute renal colic: a randomized clinical trial
PURPOSE: Although nonselective nonsteroidal anti-inflammatory drugs (nsNSAIDs) and opioids are effective treatments for acute renal colic, they are associated with adverse events (AEs). As cyclooxygenase-2 selective NSAIDs may provide a safer alternative, we compared the efficacy and safety of parecoxib versus an nsNSAID in subjects with acute renal colic. M
International braz j urol. Publicado em: 2011-12
-
6. Treatment with paracetamol, ketorolac or etoricoxib did not hinder alveolar bone healing: a histometric study in rats
Prostaglandins control osteoblastic and osteoclastic function under physiological or pathological conditions and are important modulators of the bone healing process. The non-steroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenase (COX) activity and consequently prostaglandins synthesis. Experimental and clinical evidence has indicated a risk for r
Journal of Applied Oral Science. Publicado em: 2010-12
-
7. EFEITO CLÍNICO DO USO DE PARECOXIB EM SINOVITE INDUZIDA EM PÔNEIS / EFFECT OF PARECOXIB IN INDUCED SYNOVITIS IN HORSES
Acute synovitis and capsulitis are common articular problems and can contribute to the development of a degenerative process due to the release of enzymes and inflammatory mediators. The indicated treatment for synovitis and capsulitis is based on anti-inflammatory drugs. An experimental synovitis model was used in ponies to evaluate the effect of parecoxib,
Publicado em: 2006
-
8. Estudo da interferência de diferentes dietas nutricionais sobre as ações antiinflamatória e analgésica do Etoricoxib (Arcóxia) / Study of the interference of different nutritional diets in the anti-inflammatory and analgesic actions of Etoricoxib (Arcoxia)
Etoricoxib is a new medicine expected to lead the next generation of selective inhibitors of COX-2 Presently the focus of many clinical assays it is a potent fast-action second generation coxib and the most selective of all The purpose of this study was to evaluate the interference of different nutritional diets in the anti-inflammatory and analgesic actions
Publicado em: 2006
-
9. Effect of cyclooxygenase inhibitors on gentamicin-induced nephrotoxicity in rats
The frequent use of nonsteroidal anti-inflammatory drugs (NSAID) in combination with gentamicin poses the additional risk of nephrotoxic renal failure. Cyclooxygenase-1 (COX-1) is the main enzyme responsible for the synthesis of renal vasodilator prostaglandins, while COX-2 participates predominantly in the inflammatory process. Both are inhibited by non-sel
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-07
-
10. Effect of a selective nonsteroidal anti-inflammatory inhibitor of cyclooxygenase-2 on the small bowel of rats
The pathogenesis of nonsteroidal anti-inflammatory drug (NSAID) enteropathy is a complex process involving the uncoupling of mitochondrial oxidative phosphorylation and inhibition of cyclooxygenase (COX). Rofecoxib, a selective inhibitor of COX-2, has shown less gastric damage, but the same beneficial effect is not clear in the case of the small bowel. Fifty
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-03
-
11. Nonsteroidal anti-inflammatory drug-induced duodenal ulceration and perforation in a mature rottweiler
A mature male rottweiler was evaluated for acute collapse and abdominal pain. The history consisted of concurrent administration of meloxicam and aspirin. On exploratory laparotomy, a large perforated ulcer was discovered in the proximal duodenum, with secondary peritonitis. The pathogenesis of NSAID-induced gastrointestinal ulceration and the supposed safet
-
12. Dehydration activates an NF-κB–driven, COX2-dependent survival mechanism in renal medullary interstitial cells
Renal prostaglandin (PG) synthesis is mediated by cyclooxygenase-1 and -2 (COX1 and COX2). After dehydration, the maintenance of normal renal function becomes particularly dependent upon PG synthesis. The present studies were designed to examine the potential link between medullary COX1 and COX2 expression in hypertonic stress. In response to water deprivati
American Society for Clinical Investigation.